Mitochondrial proteome design: From molecular identity to pathophysiological regulation

Abbreviations used in this paper: 2-DE two-dimensional PAGE 2D-DIGE two-dimensional difference in-gel electrophoresis ETC electron transport chain IFM interfibrillar mitochondria IH intermittent hypoxia IMM inner mitochondrial membrane iTRAQ isobaric tags for relative and absolute quantitation LC liquid chromatography LS Leigh’s syndrome MRM multiple reaction monitoring MS mass spectrometry mtDNA mitochondrial DNA OMM outer mitochondrial membrane OXPHOS oxidative phosphorylation PTM posttranslational modification RCD respiratory chain disease ROS reactive oxygen species SNO S-nitrosylation SSM subsarcolemmal mitochondria TCA tricarboxylic acid

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