Local oral immunization with synthetic peptides induces a dual mucosal IgG and salivary IgA antibody response and prevents colonization of Streptococcus mutans.

[1]  T. Lehner,et al.  Local active gingival immunization by a 3,800-molecular-weight streptococcal antigen in protection against dental caries , 1986, Infection and immunity.

[2]  T. Lehner,et al.  The helper and suppressor functions of primate T cells elicited by a 185K streptococcal antigen, as compared with the helper function elicited by a 4K streptococcal antigen. , 1985, Journal of immunology.

[3]  P. Nair,et al.  Local immune response to repeated topical antigen application in the simian labial mucosa , 1983, Infection and immunity.

[4]  T. Lehner,et al.  Immunization with purified protein antigens from Streptococcus mutans against dental caries in rhesus monkeys , 1981, Infection and immunity.

[5]  T. Lehner,et al.  Salivary antibody responses in rhesus monkeys immunized with Streptococcus mutans by the oral, submucosal or subcutaneous routes. , 1979, Archives of oral biology.

[6]  J. Zamet Book Review: The Borderland between Caries and Periodontal Disease , 1978 .

[7]  J. Mcghee,et al.  Selective induction of an immune response in human external secretions by ingestion of bacterial antigen. , 1978, The Journal of clinical investigation.

[8]  J. Mcghee,et al.  Concept of the local and common mucosal immune response. , 1978, Advances in experimental medicine and biology.

[9]  T. Lehner,et al.  A sequential bacteriological and serological investigation of Rhesus monkeys immunised against dental caries with Streptococcus mutans. , 1977, Journal of medical microbiology.

[10]  J. Mestecky,et al.  Ingestion of Streptococcus mutans induces secretory immunoglobulin A and caries immunity , 1976, Science.

[11]  Schroeder He,et al.  Pathogenesis of inflammatory periodontal disease. A summary of current work. , 1976 .

[12]  T. Lehner,et al.  Immunological and bacteriological basis for vaccination against dental caries in rhesus monkeys , 1975, Nature.

[13]  C B Anfinsen,et al.  Antibodies reactive with native lysozyme elicited by a completely synthetic antigen. , 1971, Proceedings of the National Academy of Sciences of the United States of America.