Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content.

[1]  R. Xavier,et al.  Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity , 2020, Nature Communications.

[2]  Niroshan Shanmugarajah,et al.  Bile acid composition regulates the manganese transporter Slc30a10 in intestine , 2020, The Journal of Biological Chemistry.

[3]  Minzi Deng,et al.  Down‐regulation of SLC35C1 induces colon cancer through over‐activating Wnt pathway , 2020, Journal of cellular and molecular medicine.

[4]  Jingyuan Fu,et al.  Systems genetics approach reveals cross-talk between bile acids and intestinal microbes , 2019, PLoS genetics.

[5]  J. C. Wolters,et al.  Glucose‐6‐Phosphate Regulates Hepatic Bile Acid Synthesis in Mice , 2019, Hepatology.

[6]  R. Xavier,et al.  Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk. , 2019, Circulation research.

[7]  B. Staels,et al.  Bile acid alterations in nonalcoholic fatty liver disease, obesity, insulin resistance and type 2 diabetes: what do the human studies tell? , 2019, Current opinion in lipidology.

[8]  B. Yandell,et al.  Genetic determinants of gut microbiota composition and bile acid profiles in mice , 2019, bioRxiv.

[9]  M. Fischbach,et al.  Bile acid metabolites control Th17 and Treg cell differentiation , 2018, bioRxiv.

[10]  Luke R. Thompson,et al.  Species-level functional profiling of metagenomes and metatranscriptomes , 2018, Nature Methods.

[11]  Jingyuan Fu,et al.  A system biology perspective on environment-host-microbe interactions. , 2018, Human molecular genetics.

[12]  M. Heiner-Fokkema,et al.  New insights in the multiple roles of bile acids and their signaling pathways in metabolic control , 2018, Current opinion in lipidology.

[13]  Torsten Schwede,et al.  SWISS-MODEL: homology modelling of protein structures and complexes , 2018, Nucleic Acids Res..

[14]  I. Arends,et al.  Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review , 2018, Beilstein journal of organic chemistry.

[15]  A. Molinaro,et al.  Role of Bile Acids in Metabolic Control , 2018, Trends in Endocrinology & Metabolism.

[16]  Ruixin Zhu,et al.  Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD , 2017, Gut.

[17]  M. Fobker,et al.  SLC39A8 deficiency: biochemical correction and major clinical improvement by manganese therapy , 2017, Genetics in Medicine.

[18]  Cheng Hu,et al.  Role of gut microbiota, bile acids and their cross‐talk in the effects of bariatric surgery on obesity and type 2 diabetes , 2017, Journal of diabetes investigation.

[19]  Erdogan Taskesen,et al.  Functional mapping and annotation of genetic associations with FUMA , 2017, Nature Communications.

[20]  Albert K Groen,et al.  Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats , 2017, Chronobiology international.

[21]  B. Angelin,et al.  Cholestyramine treatment of healthy humans rapidly induces transient hypertriglyceridemia when treatment is initiated. , 2017, American journal of physiology. Endocrinology and metabolism.

[22]  Eveliina Munukka,et al.  Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice , 2017, The ISME Journal.

[23]  M. Nieuwdorp,et al.  Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion. , 2016, Cell metabolism.

[24]  Shane A. McCarthy,et al.  Reference-based phasing using the Haplotype Reference Consortium panel , 2016, Nature Genetics.

[25]  W. D. de Vos,et al.  Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice , 2016, npj Biofilms and Microbiomes.

[26]  S. Neubauer,et al.  Fasting Plasma Insulin Concentrations Are Associated With Changes in Hepatic Fatty Acid Synthesis and Partitioning Prior to Changes in Liver Fat Content in Healthy Adults , 2016, Diabetes.

[27]  Duy Tin Truong,et al.  MetaPhlAn2 for enhanced metagenomic taxonomic profiling , 2015, Nature Methods.

[28]  Gangyi Yang,et al.  Overexpression of JAZF1 protected ApoE-deficient mice from atherosclerosis by inhibiting hepatic cholesterol synthesis via CREB-dependent mechanisms. , 2014, International journal of cardiology.

[29]  Torsten Seemann,et al.  Prokka: rapid prokaryotic genome annotation , 2014, Bioinform..

[30]  D. Accili,et al.  Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids , 2013, Diabetes.

[31]  M. Horie,et al.  Phenotype Variability in Patients Carrying Kcnj2 Mutations Running Title: Kimura Et Al.; Phenotype Variability in Kcnj2 Mutations , 2022 .

[32]  B. Angelin,et al.  Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19 , 2011, Journal of internal medicine.

[33]  A. von Eckardstein,et al.  Bile Acid Metabolites in Serum: Intraindividual Variation and Associations with Coronary Heart Disease, Metabolic Syndrome and Diabetes Mellitus , 2011, PloS one.

[34]  F. Kuipers,et al.  Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism , 2010, Hepatology.

[35]  P. Oliveira,et al.  Bile acids are toxic for isolated cardiac mitochondria , 2007, Cardiovascular Toxicology.

[36]  B. Angelin,et al.  Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis. , 2005, Gastroenterology.

[37]  Sander M Houten,et al.  Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. , 2004, The Journal of clinical investigation.

[38]  J. Romijn,et al.  Low-fat, high-carbohydrate and high-fat, low-carbohydrate diets decrease primary bile acid synthesis in humans. , 2004, The American journal of clinical nutrition.

[39]  P. Wright,et al.  Zinc finger proteins: new insights into structural and functional diversity. , 2001, Current opinion in structural biology.

[40]  F. Kuipers,et al.  Bile acids suppress the secretion of very‐low‐density lipoprotein by human hepatocytes in primary culture , 1996, Hepatology.

[41]  J. C. van der Molen,et al.  Determination of cholic acid and chenodeoxycholic acid pool sizes and fractional turnover rates by means of stable isotope dilution technique, making use of deuterated cholic acid and chenodeoxycholic acid. , 1988, Clinica chimica acta; international journal of clinical chemistry.

[42]  B. Angelin,et al.  Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia. , 1987, Proceedings of the National Academy of Sciences of the United States of America.