Research progress on the radio-synthesis of PET probes in microfluidic chips

Radio-synthesis of PET tracers in microfluidic chip system for imaging research could facilitate synthesis and screening of radiotracer. Moreover, modular and multi-functional microfluidic chip synthesis system could realize the combination of functional modules, synthetic automation, system integration and improvement of radiochemical protection. In this review, research progress in microfluidic chip system for radio-synthesis of PET tracers has been summarized. Key words: Molecular probes; Positron-emission tomography; Lab-on-a-chip devices; Trends