A selective and sensitive off–on probe for palladium and its application for living cell imaging

Abstract A new rhodamine B derivative T1 has been rationally synthesized and displayed selective Pd(II)-amplified absorbance and fluorescence emission above 540 nm in methanol–water. Upon the addition of Pd(II), the spirolactam ring was unfolded and a 1:1 metal-ligand complex formed, which can be used for “naked-eyes” detection. In addition, fluorescence imaging experiments of Pd 2+ in HepG2 living cells showed its valuable application in biological systems.

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