Enhanced Ionic Transport Mechanism by Gramicidin A Confined Inside Nanopores Tuned by Atomic Layer Deposition

The confinement and the understanding of ion transport through ionic channels when they are confined inside solid-state nanopores smaller than 10 nm remains a challenge. Here we report on the fabrication of biomimetic nanopores with high length (5 μm)/diameter (smaller than 10 nm) ratio obtained using both a track-etched technique and atomic layer deposition on flexible membranes. These membranes present uniform hydrophobic nanopores with a low roughness inside the pores. Gramicidin A is then confined inside nanopores (diameter 10.6, 5.7, and ∼2 nm) leading to the NaCl ionic transport mechanism through a hybrid nanopore similar to the biological ones especially for small diameter (5.7 and ∼2 nm).

[1]  P. Déjardin,et al.  Controlling potassium selectivity and proton blocking in a hybrid biological/solid-state polymer nanoporous membrane. , 2013, Nanoscale.

[2]  Natalie A. Ray,et al.  Shape-selective sieving layers on an oxide catalyst surface. , 2012, Nature Chemistry.

[3]  P. Déjardin,et al.  Nanopore sensors: from hybrid to abiotic systems. , 2012, Biosensors & bioelectronics.

[4]  R. Raghavan,et al.  Nanocrystalline-to-amorphous transition in nanolaminates grown by low temperature atomic layer deposition and related mechanical properties , 2012 .

[5]  S. Mahurin,et al.  Nanoscale Chemical Imaging of Zinc Oxide Nanowire Corrosion , 2012 .

[6]  J. Michler,et al.  Urchin-inspired zinc oxide as building blocks for nanostructured solar cells , 2012, 1204.2728.

[7]  M. Omidkhah,et al.  Separation of methane-nitrogen mixtures using synthesis vertically aligned carbon nanotube membranes , 2012 .

[8]  Nicola Pinna,et al.  Atomic Layer Deposition of Nanostructured Materials for Energy and Environmental Applications , 2012, Advanced materials.

[9]  Z. Siwy,et al.  Electric-field-induced wetting and dewetting in single hydrophobic nanopores. , 2011, Nature nanotechnology.

[10]  F. Henn,et al.  Stability of the gramicidin-A channel structure in view of nanofiltration: a computational and experimental study , 2011 .

[11]  Vincent Laporte,et al.  Highly active oxide photocathode for photoelectrochemical water reduction. , 2011, Nature materials.

[12]  G. Cao,et al.  Effect of Annealing Temperature on TiO2−ZnO Core−Shell Aggregate Photoelectrodes of Dye-Sensitized Solar Cells , 2011 .

[13]  F. Henn,et al.  New bioinspired membrane made of a biological ion channel confined into the cylindrical nanopore of a solid-state polymer. , 2011, Nano letters.

[14]  Cees Dekker,et al.  Hybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores. , 2010, Nature nanotechnology.

[15]  Steven J. Gaik,et al.  DNA translocation through an array of kinked nanopores. , 2010, Nature materials.

[16]  G. Cao,et al.  Effect of an Ultrathin TiO2 Layer Coated on Submicrometer‐Sized ZnO Nanocrystallite Aggregates by Atomic Layer Deposition on the Performance of Dye‐Sensitized Solar Cells , 2010, Advanced materials.

[17]  Lei Jiang,et al.  Energy Harvesting with Single‐Ion‐Selective Nanopores: A Concentration‐Gradient‐Driven Nanofluidic Power Source , 2010 .

[18]  J. Jur,et al.  Temperature-dependent subsurface growth during atomic layer deposition on polypropylene and cellulose fibers. , 2010, Langmuir : the ACS journal of surfaces and colloids.

[19]  Han Gao,et al.  Transparent, well-aligned TiO(2) nanotube arrays with controllable dimensions on glass substrates for photocatalytic applications. , 2010, ACS applied materials & interfaces.

[20]  Joseph G. Shapter,et al.  Structural and chemical modification of porous alumina membranes , 2009 .

[21]  Nicholas N. Watkins,et al.  Highly Sensitive, Mechanically Stable Nanopore Sensors for DNA Analysis , 2009, Advanced materials.

[22]  C. Laberty‐Robert,et al.  Design, Synthesis, Structural and Textural Characterization, and Electrical Properties of Mesoporous Thin Films Made of Rare Earth Oxide Binaries , 2009 .

[23]  M. Cassir,et al.  ZrO2–In2O3 thin layers with gradual ionic to electronic composition synthesized by atomic layer deposition for SOFC applications , 2009 .

[24]  Steven M. George,et al.  Thickness dependence of sensor response for CO gas sensing by tin oxide films grown using atomic layer deposition , 2008 .

[25]  Giovanni Neri,et al.  Vanadium oxide sensing layer grown on carbon nanotubes by a new atomic layer deposition process. , 2008, Nano letters.

[26]  J. Michler,et al.  Ordered hexagonal array of Au nanodots on Si substrate based on colloidal crystal templating , 2008, Nanotechnology.

[27]  U. Gösele,et al.  A practical, self-catalytic, atomic layer deposition of silicon dioxide. , 2008, Angewandte Chemie.

[28]  H. Haick,et al.  Highly stable organic modification of Si(111) surfaces: towards reacting Si with further functionalities while preserving the desirable chemical properties of full Si-C atop site terminations. , 2008, Journal of the American Chemical Society.

[29]  Marco Sampietro,et al.  Al2O3 as gate dielectric for organic transistors: Charge transport phenomena in poly-(3-hexylthiophene) based devices , 2008 .

[30]  Arrelaine A. Dameron,et al.  Gas Diffusion Barriers on Polymers Using Multilayers Fabricated by Al2O3 and Rapid SiO2 Atomic Layer Deposition , 2008 .

[31]  Dmitry Bedrov,et al.  Passive transport of C60 fullerenes through a lipid membrane: a molecular dynamics simulation study. , 2008, The journal of physical chemistry. B.

[32]  Joseph T Hupp,et al.  ZnO nanotube based dye-sensitized solar cells. , 2007, Nano letters.

[33]  Bernard Kippelen,et al.  Encapsulation of pentacene/C60 organic solar cells with Al2O3 deposited by atomic layer deposition , 2007 .

[34]  P. Déjardin,et al.  Flat sheet membrane with controlled variation of pore density and pore size in a direction parallel to the surface , 2007 .

[35]  Toby W Allen,et al.  Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels. , 2006, Biophysical chemistry.

[36]  K. Komvopoulos,et al.  Enhancement of the photoprotection and nanomechanical properties of polycarbonate by deposition of thin ceramic coatings , 2006 .

[37]  B. Roux,et al.  Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields. , 2006, Biophysical journal.

[38]  Laxmikant V. Kalé,et al.  Scalable molecular dynamics with NAMD , 2005, J. Comput. Chem..

[39]  Pascale Mazoyer,et al.  Evolution of materials technology for stacked-capacitors in 65 nm embedded-DRAM , 2005 .

[40]  Philippe Déjardin,et al.  Streaming potential in cylindrical pores of poly(ethylene terephthalate) track-etched membranes: variation of apparent zeta potential with pore radius. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[41]  Chi-Sun Hwang,et al.  Ultrathin Film Encapsulation of an OLED by ALD , 2005 .

[42]  Steven M. George,et al.  ZnO/Al2O3 nanolaminates fabricated by atomic layer deposition: growth and surface roughness measurements , 2002 .

[43]  Burkhard Raguse,et al.  Energy storage by the electrochemical reduction of CO2 to CO at a porous Au film , 2002 .

[44]  H. Strathmann,et al.  Membrane separation processes: Current relevance and future opportunities , 2001 .

[45]  B. Wallace.  Common structural features in gramicidin and other ion channels , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[46]  Alexander D. MacKerell,et al.  All-atom empirical potential for molecular modeling and dynamics studies of proteins. , 1998, The journal of physical chemistry. B.

[47]  Charles R. Martin,et al.  Sol−Gel Template Synthesis of Semiconductor Oxide Micro- and Nanostructures , 1997 .

[48]  B. Roux,et al.  Valence selectivity of the gramicidin channel: a molecular dynamics free energy perturbation study. , 1996, Biophysical journal.

[49]  B. Brooks,et al.  Constant pressure molecular dynamics simulation: The Langevin piston method , 1995 .

[50]  B. Wallace,et al.  The pore dimensions of gramicidin A. , 1993, Biophysical journal.

[51]  T. Darden,et al.  Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .

[52]  M Karplus,et al.  Ion transport in a model gramicidin channel. Structure and thermodynamics. , 1991, Biophysical journal.

[53]  J. Lynch,et al.  Liquid junction potentials and small cell effects in patch-clamp analysis , 1991, The Journal of Membrane Biology.

[54]  D. Sawyer,et al.  Gramicidins A, B, and C form structurally equivalent ion channels. , 1990, Biophysical journal.

[55]  J. F. Hinton,et al.  Thermodynamic parameters for the binding of divalent cations to gramicidin A incorporated into a lipid environment by Tl-205 nuclear magnetic resonance. , 1989, Biophysical journal.

[56]  W. L. Jorgensen,et al.  Comparison of simple potential functions for simulating liquid water , 1983 .

[57]  A. Strickholm.  Ionic permeability of K, Na, and Cl in potassium-depolarized nerve. Dependency on pH, cooperative effects, and action of tetrodotoxin. , 1981, Biophysical journal.

[58]  E. Neher,et al.  Ionic selectivity, saturation, and block in gramicidin a channels , 1978, The Journal of Membrane Biology.

[59]  E. Neher,et al.  Ionic selectivity, saturation and block in gramicidin A channels: , 1977, The Journal of Membrane Biology.

[60]  G. Porod,et al.  Die Röntgenkleinwinkelstreuung von dichtgepackten kolloiden Systemen , 1952 .

[61]  P. Déjardin,et al.  Structure and ionic selectivity of a hybrid polyene/artificial polymer solid state membrane , 2013 .

[62]  J. Michler,et al.  High Spatial Resolution Time-of-Flight Secondary Ion Mass Spectrometry for the Masses: A Novel Orthogonal ToF FIB-SIMS Instrument with In Situ AFM , 2012 .

[63]  Jerzy Kanicki,et al.  Thin-Film Encapsulation of Organic Light-Emitting Devices , 2007 .

[64]  G. Caffier,et al.  Selectivity for cations in potassium and gramicidin channels of the muscle fibre membrane. , 1988, Biomedica biochimica acta.

[65]  W. Pickard.  Generalizations of the goldman hodgkin katz equation , 1976 .

[66]  G. Porod.  Die Röntgenkleinwinkelstreuung von dichtgepackten kolloiden Systemen , 1953 .