Secretory Otitis Media

Those of us who are practising otologists and yet are fortunate enough to have the opportunity of doing basic investigative work can sometimes 'bridge the gap' between puzzling clinical and pathological pictures. During the course of the past four years we have studied some 400 human ear effusions cytologically and have investigated the biochemical characteristics of the effusions by newly developed microtechniques. Simultaneously we have experimentally produced effusions in animals and are studying the cytologic, chemical and pathologic changes. I hope to show that