Aptamer BC007 for neutralization of pathogenic autoantibodies directed against G-protein coupled receptors: A vision of future treatment of patients with cardiomyopathies and positivity for those autoantibodies.
暂无分享,去创建一个
Eckhard Salzsieder | Ingolf Schimke | G. Wallukat | E. Salzsieder | R. Kreutz | A. Haberland | E. Freyse | A. Schulz | R. Vetter | Reinhold Kreutz | I. Schimke | Johannes Müller | Gerd Wallukat | Roland Vetter | Johannes Müller | Annekathrin Haberland | Sabine Berg | Angela Schulz | Ernst-Joachim Freyse | S. Berg
[1] R. Hetzer,et al. Immunoadsorption therapy for dilated cardiomyopathy and pulmonary arterial hypertension. , 2013, Atherosclerosis. Supplements.
[2] R. Kunze,et al. Agonistic Autoantibodies to the α1‐Adrenergic Receptor and the β2‐Adrenergic Receptor in Alzheimer’s and Vascular Dementia , 2012, Scandinavian journal of immunology.
[3] G. Wallukat,et al. α1-Adrenergic Receptor Antibodies in Patients With Primary Hypertension , 1997 .
[4] S. Tope,et al. Aptamers as therapeutics , 2013 .
[5] Anthony D. Keefe,et al. Aptamers as therapeutics , 2010, Nature Reviews Drug Discovery.
[6] G. Wallukat,et al. Aptamer Neutralization of Beta1-Adrenoceptor Autoantibodies Isolated From Patients With Cardiomyopathies , 2011, Circulation research.
[7] R. Kunze,et al. Sera from Patients with Type 2 Diabetes Contain Agonistic Autoantibodies Against G Protein‐Coupled Receptors , 2009, Scandinavian journal of immunology.
[8] G. Wallukat,et al. Neutralization of pathogenic beta1-receptor autoantibodies by aptamers in vivo: the first successful proof of principle in spontaneously hypertensive rats , 2014, Molecular and Cellular Biochemistry.
[9] R. Hetzer,et al. Specific Removal of β1-Adrenergic Autoantibodies from Patients with Idiopathic Dilated Cardiomyopathy , 2002 .
[10] R. Hetzer,et al. Immunoadsorption can improve cardiac function in transplant candidates with non-ischemic dilated cardiomyopathy associated with diabetes mellitus. , 2015, Atherosclerosis. Supplements.
[11] R. Hetzer,et al. Specific removal of beta1-adrenergic autoantibodies from patients with idiopathic dilated cardiomyopathy. , 2002, The New England journal of medicine.
[12] R. Hetzer,et al. Long‐term benefits of immunoadsorption in β1‐adrenoceptor autoantibody‐positive transplant candidates with dilated cardiomyopathy , 2012, European journal of heart failure.
[13] J. Marquis,et al. Toxicological evaluation of oligonucleotide therapeutics. , 2000, Current opinion in molecular therapeutics.
[14] Yidan Wang,et al. The Correlation between Peripartum Cardiomyopathy and Autoantibodies against Cardiovascular Receptors , 2014, PloS one.
[15] R. Kunze,et al. Antibodies to the α1-Adrenergic Receptor Cause Vascular Impairments in Rat Brain as Demonstrated by Magnetic Resonance Angiography , 2012, PloS one.
[16] G. Wallukat,et al. Alpha 1-adrenergic receptor antibodies in patients with primary hypertension. , 1997, Hypertension.
[17] R. Hetzer,et al. Reduced oxidative stress in parallel to improved cardiac performance one year after selective removal of anti‐beta 1‐adrenoreceptor autoantibodies in patients with idiopathic dilated cardiomyopathy: data of a preliminary study , 2005, Journal of clinical apheresis.
[18] G. Wallukat,et al. Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients. , 2010, Journal of the American College of Cardiology.
[19] G. Wallukat,et al. Aptamer binding and neutralization of β1-adrenoceptor autoantibodies: basics and a vision of its future in cardiomyopathy treatment. , 2011, Trends in cardiovascular medicine.
[20] M. Fu. Anti-M2 muscarinic receptor autoantibodies and idiopathic dilated cardiomyopathy. , 1996, International journal of cardiology.
[21] G. Wallukat,et al. Effects of the serum gamma globulin fraction of patients with allergic asthma and dilated cardiomyopathy on chronotropic beta adrenoceptor function in cultured neonatal rat heart myocytes. , 1987, Biomedica biochimica acta.
[22] G. Wallukat,et al. Agonistic autoantibodies directed against G-protein-coupled receptors and their relationship to cardiovascular diseases , 2014, Seminars in Immunopathology.