Poly(ethylene glycol) (PEG)-lactic acid nanocarrier-based degradable hydrogels for restoring the vaginal microenvironment.
暂无分享,去创建一个
[1] M. Einstein,et al. Phase I Randomized Safety Study of Twice Daily Dosing of Acidform Vaginal Gel: Candidate Antimicrobial Contraceptive , 2012, PloS one.
[2] Karyn G. Robinson,et al. In situ crosslinkable heparin-containing poly(ethylene glycol) hydrogels for sustained anticoagulant release. , 2012, Journal of biomedical materials research. Part A.
[3] S. Love,et al. Influence of Molecular Size on the Retention of Polymeric Nanocarrier Diagnostic Agents in Breast Ducts , 2012, Pharmaceutical Research.
[4] J. Remon,et al. Vaginal distribution and retention of a multiparticulate drug delivery system, assessed by gamma scintigraphy and magnetic resonance imaging. , 2012, International journal of pharmaceutics.
[5] R. Cone,et al. In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide , 2011, BMC infectious diseases.
[6] M. Chikindas,et al. The aetiology of bacterial vaginosis , 2011, Journal of applied microbiology.
[7] Taha Taha,et al. Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women , 2011, AIDS.
[8] P. Sinko,et al. Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries. , 2011, Biomaterials.
[9] S. Witkin,et al. Contemporary perspectives on vaginal pH and lactobacilli. , 2011, American journal of obstetrics and gynecology.
[10] J. Pudney,et al. Development of an in vitro alternative assay method for vaginal irritation. , 2011, Toxicology.
[11] Thomas J. Smith,et al. Advances in microbicide vaginal rings. , 2010, Antiviral research.
[12] S. McCormack,et al. The last decade of microbicide clinical trials in Africa: from hypothesis to facts , 2010, AIDS.
[13] Lynn Morris,et al. Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women , 2010, Science.
[14] J. Nuttall,et al. Microbicides in the Prevention of HIV Infection , 2010, Drugs.
[15] A. Servin,et al. Individual and co-operative roles of lactic acid and hydrogen peroxide in the killing activity of enteric strain Lactobacillus johnsonii NCC933 and vaginal strain Lactobacillus gasseri KS120.1 against enteric, uropathogenic and vaginosis-associated pathogens. , 2010, FEMS microbiology letters.
[16] L. van Damme,et al. Results of a safety and feasibility study of the diaphragm used with ACIDFORM Gel or K-Y Jelly. , 2010, Contraception.
[17] P. Sinko,et al. Doxycycline loaded poly(ethylene glycol) hydrogels for healing vesicant-induced ocular wounds. , 2010, Biomaterials.
[18] S. Kannan,et al. Drug release characteristics of PAMAM dendrimer-drug conjugates with different linkers. , 2010, International journal of pharmaceutics.
[19] P. Mastromarino,et al. Inhibition of herpes simplex virus type 2 by vaginal lactobacilli. , 2009, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
[20] T. Hope,et al. Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus , 2009, Journal of Virology.
[21] P. Sinko,et al. Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[22] R. Mumper,et al. Formulating a Sulfonated Antiviral Dendrimer in a Vaginal Microbicidal Gel Having Dual Mechanisms of Action , 2009, Drug development and industrial pharmacy.
[23] C. Dezzutti,et al. Targeted Delivery of PSC-RANTES for HIV-1 Prevention using Biodegradable Nanoparticles , 2009, Pharmaceutical Research.
[24] B. Friedland,et al. Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial , 2008, The Lancet.
[25] J. Justman,et al. Vaginal microbicides and the prevention of HIV transmission. , 2008, The Lancet. Infectious diseases.
[26] A. Adimora,et al. Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies , 2008, AIDS.
[27] J. H. van de Wijgert,et al. Vaginal microbicides: the importance of effective distribution, retention and coating of the mucosa. , 2008, AIDS.
[28] K. Barnhart,et al. Contraceptive Efficacy of a Novel Spermicidal Microbicide Used With a Diaphragm: A Randomized Controlled Trial , 2007, Obstetrics and gynecology.
[29] L. Grohskopf,et al. Preclinical Testing of Candidate Topical Microbicides for Anti-Human Immunodeficiency Virus Type 1 Activity and Tissue Toxicity in a Human Cervical Explant Culture , 2007, Antimicrobial Agents and Chemotherapy.
[30] C. Tsakiroglou,et al. Liposomal drugs dispersed in hydrogels. Effect of liposome, drug and gel properties on drug release kinetics. , 2007, Colloids and surfaces. B, Biointerfaces.
[31] D. Katz,et al. Temperature and pH sensitive hydrogels: an approach towards smart semen-triggered vaginal microbicidal vehicles. , 2007, Journal of pharmaceutical sciences.
[32] Sarah L. Kieweg,et al. Biophysical analysis of prototype microbicidal gels. , 2007, Journal of pharmaceutical sciences.
[33] A. Woolfson,et al. Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide. , 2006, International journal of pharmaceutics.
[34] Robert A. Anderson,et al. ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations. , 2006, The Journal of infectious diseases.
[35] R. Cone,et al. Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission , 2006, BMC infectious diseases.
[36] F. Petraglia,et al. [Effectiveness of oral administration of Lactobacillus paracasei subsp. paracasei F19 in association with vaginal suppositories of Lactobacillus acidofilus in the treatment of vaginosis and in the prevention of recurrent vaginitis]. , 2006, Minerva ginecologica.
[37] Sally Freeman,et al. Synthesis, characterization and stability of dendrimer prodrugs. , 2006, International journal of pharmaceutics.
[38] H. Maeda,et al. The EPR Effect and Polymeric Drugs: A Paradigm Shift for Cancer Chemotherapy in the 21st Century , 2005 .
[39] A. Woolfson,et al. Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings. , 2005, The Journal of antimicrobial chemotherapy.
[40] K. Barnhart,et al. In vivo distribution of a vaginal gel: MRI evaluation of the effects of gel volume, time and simulated intercourse. , 2004, Contraception.
[41] M. Nader-Macías,et al. Growth and lactic acid production by vaginal Lactobacillus acidophilus CRL 1259, and inhibition of uropathogenic Escherichia coli. , 2003, Journal of medical microbiology.
[42] Christina H. Park,et al. Antimicrobial components of vaginal fluid. , 2002, American journal of obstetrics and gynecology.
[43] F. Krebs,et al. Comparative In Vitro Sensitivities of Human Immune Cell Lines, Vaginal and Cervical Epithelial Cell Lines, and Primary Cells to Candidate Microbicides Nonoxynol 9, C31G, and Sodium Dodecyl Sulfate , 2002, Antimicrobial Agents and Chemotherapy.
[44] R. Langer,et al. Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications , 2002, Science.
[45] K. Whaley,et al. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. , 2001, Human reproduction.
[46] Robert A. Anderson,et al. Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM). , 2001, Contraception.
[47] J. Peipert,et al. Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[48] B. Chohan,et al. Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition. , 1999, The Journal of infectious diseases.
[49] K. Whaley,et al. Acid Production by Vaginal Flora In Vitro Is Consistent with the Rate and Extent of Vaginal Acidification , 1999, Infection and Immunity.
[50] D R Hoover,et al. Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV , 1998, AIDS.
[51] D. Taylor-Robinson,et al. Safety study of nonoxynol-9 as a vaginal microbicide: evidence of adverse effects. , 1998, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.
[52] N. Sewankambo,et al. HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis , 1997, The Lancet.
[53] J. Humphries,et al. Spreading and Retention of Vaginal Formulations in Post-Menopausal Women as Assessed by Gamma Scintigraphy , 1997, Pharmaceutical Research.
[54] K. Nelson,et al. Bacterial vaginosis and HIV seroprevalence among female commercial sex workers in Chiang Mai, Thailand , 1995, AIDS.
[55] S. Hillier. Diagnostic microbiology of bacterial vaginosis. , 1993, American journal of obstetrics and gynecology.
[56] W. Lang. Vaginal acidity and pH; a review. , 1955, Obstetrical & gynecological survey.
[57] M. P. Gonçalves,et al. Rheological properties of vaginal hydrophilic polymer gels. , 2009, Current drug delivery.
[58] M. Falagas,et al. Probiotics for the treatment of women with bacterial vaginosis , 2007 .
[59] Prashini Moodley,et al. Interrelationships among human immunodeficiency virus type 1 infection, bacterial vaginosis, trichomoniasis, and the presence of yeasts. , 2002, The Journal of infectious diseases.
[60] K. Whaley,et al. Boskey, E.R., Cone, R.A., Whaley, K.J. & Moench, T.R. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. Hum. Reprod. 16, 1809-1813 , 2001 .
[61] Ş. Tavukçuoǧlu,et al. Alternative treatment for bacterial vaginosis in pregnant patients; restoration of vaginal acidity and flora. , 1996, Archives of AIDS research.
[62] D. Lindell,et al. Bacterial vaginosis and the effect of intermittent prophylactic treatment with an acid lactate gel. , 1990, Gynecologic and obstetric investigation.