Monitoring of lobectomy in cystic fibrosis with electrical impedance tomography – a new diagnostic tool

Abstract Electrical impedance tomography (EIT) is a radiation-free technique generating cross-sectional images of the lung. EIT visualizes global and regional ventilation by illustrating the distribution of electrical bioimpedance. With an electrode belt around the patient’s thorax, rotating injection-couples of a harmless alternating current allow voltage measurement of the remaining electrodes. This enables the reconstruction of a tomogram with highly dynamic changes within ventilation. We report on a female six-year-old patient with cystic fibrosis and complete destruction of the upper and middle lobe of the right lung. Lobectomy, a rare therapeutic option in patients with cystic fibrosis that needs to be considered in cases of severe localized destruction, was performed. We show a pre- and postoperative documentation of static (radiology) and dynamic investigation tools (spirometry) in correlation with EIT as a new non-invasive and radiation-free diagnostic tool for this patient group.

[1]  J. Stocks,et al.  Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis , 2004, Thorax.

[2]  J. Hankinson,et al.  Standardization of spirometry. , 1988, The American review of respiratory disease.

[3]  N. Weiler,et al.  Spatial and temporal heterogeneity of regional lung ventilation determined by electrical impedance tomography during pulmonary function testing. , 2012, Journal of applied physiology.

[4]  T. Spray,et al.  Paediatric lung transplantation , 2004, European Respiratory Journal.

[5]  Knut Möller,et al.  Regional airway obstruction in cystic fibrosis determined by electrical impedance tomography in comparison with high resolution CT , 2013, Physiological measurement.

[6]  Steffen Leonhardt,et al.  Assessment of regional lung recruitment and derecruitment during a PEEP trial based on electrical impedance tomography , 2008, Intensive Care Medicine.

[7]  Zhanqi Zhao,et al.  Regional ventilation in cystic fibrosis measured by electrical impedance tomography. , 2012, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[8]  L. Reid,et al.  Pulmonary Resection in Cystic Fibrosis , 1972, Archives of disease in childhood.

[9]  Steffen Leonhardt,et al.  Electrical impedance tomography: the holy grail of ventilation and perfusion monitoring? , 2012, Intensive Care Medicine.

[10]  Annette Kopp-Schneider,et al.  Morphologic and functional scoring of cystic fibrosis lung disease using MRI. , 2012, European Journal of Radiology.

[11]  Eleonora Carlesso,et al.  The role of CT-scan studies for the diagnosis and therapy of acute respiratory distress syndrome. , 2006, Clinics in chest medicine.

[12]  P. Camargos,et al.  Lung resection in cystic fibrosis: A survival analysis , 2008, Pediatric pulmonology.

[13]  S. Leonhardt,et al.  Electrical Impedance tomography : new diagnostic possibilities using regional time constant map , 2012 .