论文信息 - Choice Behavior of Drosophila Facing Contradictory Visual Cues

Choice Behavior of Drosophila Facing Contradictory Visual Cues

We studied the underlying neural mechanism of a simple choice behavior between competing alternatives in Drosophila. In a flight simulator, individual flies were conditioned to choose one of two flight paths in response to color and shape cues; after the training, they were tested with contradictory cues. Wild-type flies made a discrete choice that switched from one alternative to the other as the relative salience of color and shape cues gradually changed, but this ability was greatly diminished in mutant (mbm1 ) flies with miniature mushroom bodies or with hydroxyurea ablation of mushroom bodies. Thus,Drosophila genetics may be useful for elucidating the neural basis of choice behavior.

A Guo | A. Guo | Shiming Tang | S Tang

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