Rare-variant association testing for sequencing data with the sequence kernel association test.
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Xihong Lin | M. Boehnke | T. Cai | Yun Li | Seunggeun Lee | Michael C. Wu | Michael C. Wu | Yun Li | Michael C. Wu | M. Wu | Michael C. Wu | Xihong Lin | M. Boehnke | Tianxi Cai | Tianxi Cai
[1] Kathryn Roeder,et al. Testing for an Unusual Distribution of Rare Variants , 2011, PLoS genetics.
[2] Power and sample size calculations for designing rare variant sequencing association studies , 2011 .
[3] Yun Li,et al. Extending rare-variant testing strategies: analysis of noncoding sequence and imputed genotypes. , 2010, American journal of human genetics.
[4] Eleftheria Zeggini,et al. Rare variant association analysis methods for complex traits. , 2010, Annual review of genetics.
[5] D. Altshuler,et al. A map of human genome variation from population-scale sequencing , 2010, Nature.
[6] Lee-Jen Wei,et al. Pooled Association Tests for Rare Variants in Exon-Resequencing Studies , 2010 .
[7] Deanne M. Taylor,et al. Powerful SNP-set analysis for case-control genome-wide association studies. , 2010, American journal of human genetics.
[8] L. Carvajal-Carmona,et al. Challenges in the identification and use of rare disease-associated predisposition variants. , 2010, Current opinion in genetics & development.
[9] Jason H. Moore,et al. Missing heritability and strategies for finding the underlying causes of complex disease , 2010, Nature Reviews Genetics.
[10] Wei Pan,et al. A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants , 2010, Human Heredity.
[11] Pierre Lafaye de Micheaux,et al. Computing the distribution of quadratic forms: Further comparisons between the Liu-Tang-Zhang approximation and exact methods , 2010, Comput. Stat. Data Anal..
[12] Olivier Harismendy,et al. Accurate detection and genotyping of SNPs utilizing population sequencing data. , 2010, Genome research.
[13] E. Zeggini,et al. An Evaluation of Statistical Approaches to Rare Variant Analysis in Genetic Association Studies , 2009, Genetic epidemiology.
[14] Wei Pan,et al. Asymptotic tests of association with multiple SNPs in linkage disequilibrium , 2009, Genetic epidemiology.
[15] F. Collins,et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits , 2009, Proceedings of the National Academy of Sciences.
[16] K. Frazer,et al. Common vs. rare allele hypotheses for complex diseases. , 2009, Current opinion in genetics & development.
[17] Huanming Yang,et al. SNP detection for massively parallel whole-genome resequencing. , 2009, Genome research.
[18] Suzanne M. Leal,et al. Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies , 2009, PLoS genetics.
[19] W. Ansorge. Next-generation DNA sequencing techniques. , 2009, New biotechnology.
[20] S. Browning,et al. A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic , 2009, PLoS genetics.
[21] Huan Liu,et al. A new chi-square approximation to the distribution of non-negative definite quadratic forms in non-central normal variables , 2009, Comput. Stat. Data Anal..
[22] Eric Boerwinkle,et al. Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. , 2008, The Journal of clinical investigation.
[23] S. Henikoff,et al. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm , 2009, Nature Protocols.
[24]
R. Durbin,et al.
Mapping Quality Scores Mapping Short Dna Sequencing Reads and Calling Variants Using P ,
2022
.
[25]
Amy E. Hawkins,et al.
DNA sequencing of a cytogenetically normal acute myeloid leukemia genome
,
2008,
Nature.
[26]
S. Leal,et al.
Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data.
,
2008,
American journal of human genetics.
[27]
E. Mardis.
Next-generation DNA sequencing methods.
,
2008,
Annual review of genomics and human genetics.
[28]
Dawei Liu,et al.
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models
,
2008,
BMC Bioinformatics.
[29]
Xihong Lin,et al.
A powerful and flexible multilocus association test for quantitative traits.
,
2008,
American journal of human genetics.
[30]
Xihong Lin,et al.
Semiparametric Regression of Multidimensional Genetic Pathway Data: Least‐Squares Kernel Machines and Linear Mixed Models
,
2007,
Biometrics.
[31]
W. Thilly,et al.
A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: a cohort allelic sums test (CAST).
,
2007,
Mutation research.
[32]
D. Reich,et al.
Principal components analysis corrects for stratification in genome-wide association studies
,
2006,
Nature Genetics.
[33]
S. Gabriel,et al.
Calibrating a coalescent simulation of human genome sequence variation.
,
2005,
Genome research.
[34]
James R. Knight,et al.
Genome sequencing in microfabricated high-density picolitre reactors
,
2005,
Nature.
[35]
Xihong Lin,et al.
Hypothesis testing in semiparametric additive mixed models.
,
2003,
Biostatistics.
[36]
P. Bork,et al.
Human non-synonymous SNPs: server and survey.
,
2002,
Nucleic acids research.
[37]
F. Fleuret,et al.
Scale-Invariance of Support Vector Machines based on the Triangular Kernel
,
2001
.
[38]
Nello Cristianini,et al.
An Introduction to Support Vector Machines and Other Kernel-based Learning Methods
,
2000
.
[39]
Xihong Lin.
Variance component testing in generalised linear models with random effects
,
1997
.