The Mathematical Foundations of 3D Compton Scatter Emission Imaging

The mathematical principles of tomographic imaging using detected (unscattered) X- or gamma-rays are based on the two-dimensional Radon transform and many of its variants. In this paper, we show that two new generalizations, called conical Radon transforms, are related to three-dimensional imaging processes based on detected Compton scattered radiation. The first class of conical Radon transform has been introduced recently to support imaging principles of collimated detector systems. The second class is new and is closely related to the Compton camera imaging principles and invertible under special conditions. As they are poised to play a major role in future designs of biomedical imaging systems, we present an account of their most important properties which may be relevant for active researchers in the field.

[1]  F. Natterer The Mathematics of Computerized Tomography , 1986 .

[2]  Habib Zaidi,et al.  Determination of the attenuation map in emission tomography. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[3]  ITEM—QM solutions for EM problems in image reconstruction exemplary for the Compton Camera , 2002 .

[4]  G T Gullberg,et al.  Application of spherical harmonics to image reconstruction for the Compton camera. , 1998, Physics in medicine and biology.

[5]  J. M. Nightingale,et al.  Gamma-radiation imaging system based on the Compton effect , 1977 .

[6]  A. Cormack Representation of a Function by Its Line Integrals, with Some Radiological Applications , 1963 .

[7]  Morgan Rh,et al.  An analysis of the physical factors controlling the diagnostic quality of roentgen images; contrast and the film contrast factor. , 1946 .

[8]  Roman Novikov,et al.  Une formule d'inversion pour la transformation d'un rayonnement X atténué , 2001 .

[9]  Manbir Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements , 1983 .

[10]  Harrison H. Barrett,et al.  III The Radon Transform and Its Applications , 1984 .

[11]  M. Nguyen,et al.  A novel inverse problem in γ-rays emission imaging , 2004 .

[12]  Habib Zaidi,et al.  Scatter modelling and compensation in emission tomography , 2004, European Journal of Nuclear Medicine and Molecular Imaging.

[13]  L. Parra,et al.  Reconstruction of cone-beam projections from Compton scattered data , 1999, 1999 IEEE Nuclear Science Symposium. Conference Record. 1999 Nuclear Science Symposium and Medical Imaging Conference (Cat. No.99CH37019).

[14]  M. Nguyen,et al.  Apparent image formation by Compton-scattered photons in gamma-ray imaging , 2001, IEEE Signal Processing Letters.

[15]  Paul C. Johns,et al.  Medical x-ray imaging with scattered photons , 2017, Other Conferences.

[16]  Frank Natterer,et al.  On the inversion of the attenuated Radon transform , 1979 .

[17]  D. Verschuur,et al.  Applications of the generalized radon transform , 1992 .

[18]  P. C. Johns,et al.  Scattered radiation in diagnostic radiology: magnitudes, effects and methods of reduction , 1983 .

[19]  T. Tomitani,et al.  Image reconstruction from limited angle Compton camera data , 2002, Physics in medicine and biology.

[20]  G. Beylkin The inversion problem and applications of the generalized radon transform , 1984 .

[21]  F. Sommen,et al.  The general quadratic Radon transform , 1998 .

[22]  Philip J. Bones,et al.  Towards direct reconstruction from a gamma camera based on Compton scattering , 1994, IEEE Trans. Medical Imaging.

[23]  O. Klein,et al.  Über die Streuung von Strahlung durch freie Elektronen nach der neuen relativistischen Quantendynamik von Dirac , 1929 .

[24]  D. Doria,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements. , 1983, Medical physics.

[25]  A. Cormack Radon’s problem for some surfaces in ${\bf R}\sp n$ , 1987 .

[26]  A. Cormack Radon's Problem for Some Surfaces in R n , 1987 .

[27]  Mai K. Nguyen,et al.  Radon transforms on a class of cones with fixed axis direction , 2005 .

[28]  Manbir Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part I: Theoretical considerations and design criteria , 1983 .

[29]  Eric Todd Quinto,et al.  A Radon transform on spheres through the origin in ⁿ and applications to the Darboux equation , 1980 .

[30]  C E Floyd,et al.  Energy and spatial distribution of multiple order Compton scatter in SPECT: a Monte Carlo investigation. , 1984, Physics in medicine and biology.

[31]  T. Tomitani,et al.  An analytical image reconstruction algorithm to compensate for scattering angle broadening in Compton cameras. , 2003, Physics in medicine and biology.

[32]  J. M. Nightingale,et al.  A proposed γ camera , 1974, Nature.

[33]  Mai K. Nguyen,et al.  On an integral transform and its inverse in nuclear imaging , 2002 .

[34]  P. Grangeat Mathematical framework of cone beam 3D reconstruction via the first derivative of the radon transform , 1991 .

[35]  H Zaidi,et al.  Relevance of accurate Monte Carlo modeling in nuclear medical imaging. , 1999, Medical physics.

[36]  S. Deans A unified radon inversion formula , 1978 .