A Case of Small Cell Carcinoma of the Supraglottis

Small cell carcinoma is primarily a lung malignancy occurring rarely in extra pulmonary sites such as the larynx, nasal cavity, paranasal sinuses, and oral cavity. The diagnosis was based on histological investigation expanded with immunohistochemical tests of a fragment of a tissue. The immunohistochemical stain was positive for synaptophysin, CD56 and cytokeratin. So we diagnosed small cell carcinoma. The treatment of small cell carcinoma diagnosis differed from the treatment of other neuroendocrine carcinomas and squamous cell carcinomas of the larynx. We report a case of 72-year-old man with a rare case of small cell carcinoma in the supraglottic region and a brief review of literature.� Korean J Otorhinolaryngol-Head Neck Surg 2010;53:784-6 Key WordsZZSupraglottis ㆍSmall cell ㆍCarcinoma.