A systematic framework for the design, simulation and optimization of personalized healthcare: Making and healing blood
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Efstratios N. Pistikopoulos | Athanasios Mantalaris | Ruth Misener | Eirini Velliou | Maria Rende | Nicki Panoskaltsis | María Fuentes Garí | Eleni Pefani | E. Pistikopoulos | R. Misener | A. Mantalaris | N. Panoskaltsis | E. Velliou | M. Rende | E. Pefani
[1] H. Preisler,et al. Distribution of cell cycle times amongst the leukemia cells within individual patients with acute myelogenous leukemia. , 1995, Leukemia research.
[2] Leon Hirsch. Bioreactors For Tissue Engineering Principles Design And Operation , 2016 .
[3] C. Maranas,et al. Recent advances in the reconstruction of metabolic models and integration of omics data. , 2014, Current opinion in biotechnology.
[4] K. Kaushansky,et al. Comprar Williams Hematology 8th Ed + DVD | Ernest Beutler | 9780071621519 | Mcgraw-Hill Education , 2010 .
[5] David O. Morgan,et al. The Cell Cycle: Principles of Control , 2014 .
[6] Howard C. Zisser,et al. Clinical Evaluation of a Personalized Artificial Pancreas , 2013, Diabetes Care.
[7] U. Günther,et al. Hypoxia Triggers Major Metabolic Changes in AML Cells without Altering Indomethacin-Induced TCA Cycle Deregulation , 2010, ACS chemical biology.
[8] Athanasios Mantalaris,et al. Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds. , 2011, Biomaterials.
[9] Andreas A Linninger,et al. Interspecies scaling in pharmacokinetics: a novel whole-body physiologically based modeling framework to discover drug biodistribution mechanisms in vivo. , 2012, Journal of pharmaceutical sciences.
[10] Efstratios N. Pistikopoulos,et al. A mathematical model of subpopulation kinetics for the deconvolution of leukaemia heterogeneity , 2015, Journal of The Royal Society Interface.
[11] Efstratios N. Pistikopoulos,et al. 'Closing the loop' in biological systems modeling - From the in silico to the in vitro , 2011, Autom..
[12] L. Geris,et al. The importance of vascularization for successful bone tissue engineering , 2014 .
[13] R. Henschler,et al. Hematopoietic recovery of ex vivo perfusion culture expanded bone marrow and unexpanded peripheral blood progenitors after myeloablative chemotherapy , 2001, Bone Marrow Transplantation.
[14] Catherine Marcucci,et al. The American Rare Donor Program. , 2013, Journal of critical care.
[15] Henri Wajcman,et al. Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo , 2002, Nature Biotechnology.
[16] Efstratios N. Pistikopoulos,et al. Modeling and Analysis of Individualized Pharmacokinetics and Pharmacodynamics for Volatile Anesthesia , 2014, IEEE Transactions on Biomedical Engineering.
[17] Harvey M. Wagner,et al. Global Sensitivity Analysis , 1995, Oper. Res..
[18] I. Sobola,et al. Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates , 2001 .
[19] Efstratios N. Pistikopoulos,et al. Robust Superstructure Optimisation of a Bioreactor that Produces Red Blood Cells , 2014 .
[20] Athanasios Mantalaris,et al. Engineering a mimicry of bone marrow tissue ex vivo. , 2005, Journal of bioscience and bioengineering.
[21] M. Berridge,et al. The level of glycolytic metabolism in acute myeloid leukemia blasts at diagnosis is prognostic for clinical outcome , 2011, Journal of leukocyte biology.
[22] E. Pistikopoulos,et al. Key environmental stress biomarker candidates for the optimisation of chemotherapy treatment of leukaemia , 2014 .
[23] Efstratios N. Pistikopoulos,et al. Chemotherapy Drug Scheduling for the Induction Treatment of Patients With Acute Myeloid Leukemia , 2014, IEEE Transactions on Biomedical Engineering.
[24] Jeremy C. Pamplin,et al. A bedside communication tool did not improve the alignment of a multidisciplinary team's goals for intensive care unit patients. , 2013, Journal of critical care.
[25] Raj Jena,et al. Optimal dosing of cancer chemotherapy using model predictive control and moving horizon state/parameter estimation , 2012, Comput. Methods Programs Biomed..
[26] Lars K Nielsen,et al. Blood cell manufacture: current methods and future challenges. , 2009, Trends in biotechnology.
[27] Arkadi Nemirovski,et al. Robust solutions of Linear Programming problems contaminated with uncertain data , 2000, Math. Program..
[28] E. Pistikopoulos,et al. Towards unravelling the kinetics of an acute myeloid leukaemia model system under oxidative and starvation stress: a comparison between two- and three-dimensional cultures , 2015, Bioprocess and Biosystems Engineering.
[29] L. Douay,et al. Large‐scale production of red blood cells from stem cells: What are the technical challenges ahead? , 2014, Biotechnology journal.
[30] Gürkan Sin,et al. A computer-aided framework for development, identification and management of physiologically-based pharmacokinetic models , 2014, Comput. Chem. Eng..
[31] Athanasios Mantalaris,et al. Biology Of Mixed Phenotype Acute Leukemia In Successful Long-Term Cytokine-Free Three-Dimensional (3D) Static and Perfused 3D Hollow-Fibre Bioreactor Culture , 2013 .
[32] Efstratios N. Pistikopoulos,et al. Design of optimal patient-specific chemotherapy protocols for the treatment of acute myeloid leukemia (AML) , 2013, Comput. Chem. Eng..
[33] L. Braddy,et al. Antigen‐matched donor blood in the transfusion management of patients with sickle cell disease , 1994, Transfusion.
[34] Yongchang Wei,et al. Involvement of Oxidative Stress in the Relapse of Acute Myeloid Leukemia* , 2010, The Journal of Biological Chemistry.
[35] Hugo Macedo. A novel 3D dual hollow fibre bioreactor for the production of human red blood cells , 2011 .
[36] Efstratios N. Pistikopoulos,et al. Global superstructure optimisation of red blood cell production in a parallelised hollow fibre bioreactor , 2014, Comput. Chem. Eng..
[37] Athanasios Mantalaris,et al. The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia. , 2010, Biomaterials.
[38] Sergei S. Kucherenko,et al. On global sensitivity analysis of quasi-Monte Carlo algorithms , 2005, Monte Carlo Methods Appl..
[39] Robert S. Parker,et al. Clinically relevant cancer chemotherapy dose scheduling via mixed-integer optimization , 2009, Comput. Chem. Eng..
[40] Efstratios N. Pistikopoulos,et al. Modelling of the Insulin Delivery System for patients with Type 1 Diabetes Mellitus , 2011 .
[41] Efstratios N. Pistikopoulos,et al. A framework for the design, modeling and optimization of biomedical systems , 2014 .
[42] Maria Margarida Diogo,et al. Stem cell cultivation in bioreactors. , 2011, Biotechnology advances.
[43] Athanasios Mantalaris,et al. Simulation of ex vivo bone marrow culture: Application to chronic myeloid leukaemia growth model , 2012 .
[44] Efstratios N. Pistikopoulos,et al. Global Sensitivity Analysis Challenges in Biological Systems Modeling , 2009 .
[45] Christodoulos A. Floudas,et al. A Framework for Globally Optimizing Mixed-Integer Signomial Programs , 2013, Journal of Optimization Theory and Applications.
[46] Efstratios N. Pistikopoulos,et al. Developing a cyclin blueprint as a tool for mapping the cell cycle in GS-NS0 , 2013 .
[47] Gilles Clermont,et al. A model of neutrophil dynamics in response to inflammatory and cancer chemotherapy challenges , 2013, Comput. Chem. Eng..
[48] Ioannis P. Androulakis,et al. A chemical engineer's perspective on health and disease , 2014, Comput. Chem. Eng..
[49] Efstratios N. Pistikopoulos,et al. A Cyclin Distributed Cell Cycle Model in GS-NS0 , 2014 .
[50] Graeme Wake,et al. A mathematical model for analysis of the cell cycle in cell lines derived from human tumors , 2003, Journal of mathematical biology.
[51] Christodoulos A. Floudas,et al. GloMIQO: Global mixed-integer quadratic optimizer , 2012, Journal of Global Optimization.
[52] Michael C Mackey,et al. A mathematical model of hematopoiesis--I. Periodic chronic myelogenous leukemia. , 2005, Journal of theoretical biology.