Acute Pancreatitis in Pregnancy: Three Case Reports

Acute pancreatitis is a rare condition during pregnancy, with peculiar specificities and particular findings. We report a series of 03 cases of pregnant women, treated for acute pancreatitis from 2016 to 2020. Their average age was 34.33 years and the diagnosis was based on clinical-biological clues: epigastric pain with strong elevation of lipasemia. Biliary etiology was confirmed in all patients initially by ultrasounds. Two patients had benign pancreatitis of favorable evolution. The third patient presented with a clinically severe pancreatitis and systemic inflammatory response syndrome, multiple organ failure syndrome with maternal and fetal deaths. Treatment was mainly symptomatic (medical), followed by cholecystectomy after delivery. Acute pancreatitis during pregnancy is a real threat for both the maternal and fetal prognosis and is a differential diagnosis that must be kept in mind for prompt management.

[1]  G. Carles,et al.  [Acute pancreatitis and pregnancy: Cases study and literature review]. , 2015, Journal de gynecologie, obstetrique et biologie de la reproduction.

[2]  D. Luton,et al.  Acute pancreatitis during pregnancy: a review , 2014, Journal of Perinatology.

[3]  John Baillie,et al.  American College of Gastroenterology Guidelines: Management of Acute Pancreatitis , 2013 .

[4]  Osamuyimen O. Igbinosa,et al.  Pregnancy associated pancreatitis revisited. , 2013, Clinics and research in hepatology and gastroenterology.

[5]  H. Brooks,et al.  Acute pancreatitis in pregnancy: review of three cases and anaesthetic management. , 2012, International journal of obstetric anesthesia.

[6]  D. S̆timac,et al.  Acute pancreatitis during pregnancy , 2011, European journal of gastroenterology & hepatology.

[7]  Weiqin Li,et al.  Severe Acute Pancreatitis During Pregnancy: Eleven Years Experience from a Surgical Intensive Care Unit , 2011, Digestive Diseases and Sciences.

[8]  R. Brunelli,et al.  Acute abdominal and pelvic pain in pregnancy: MR imaging as a valuable adjunct to ultrasound? , 2011, Abdominal Imaging.

[9]  D. Luton,et al.  Management of necrotizing pancreatitis in the third trimester of pregnancy , 2009, Archives of Gynecology and Obstetrics.

[10]  W. Grobman,et al.  Pancreatitis in Pregnancy , 2008, Obstetrics and gynecology.

[11]  S. Ashley,et al.  Acute Pancreatitis and Pregnancy: A 10-Year Single Center Experience , 2007, Journal of Gastrointestinal Surgery.

[12]  A. Dimitriadis,et al.  Staging of severity and prognosis of acute pancreatitis by computed tomography and magnetic resonance imaging-a comparative study. , 2007, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[13]  M. Amraoui,et al.  PANCREATITE ET GROSSESSE , 1997 .

[14]  K. Hunt,et al.  Management of pancreatitis complicating pregnancy. , 1994, The American surgeon.

[15]  J. Riemann,et al.  [Acute pancreatitis in pregnancy]. , 1981, Die Medizinische Welt.