Using genome-wide mapping in the mouse to identify genes that influence drug response.

[1]  C. Amos,et al.  Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice. , 2002, Human molecular genetics.

[2]  A. C. Collins,et al.  Variability in response to nicotine in the LSxSS RI strains: potential role of polymorphisms in alpha4 and alpha6 nicotinic receptor genes. , 2002, Pharmacogenetics.

[3]  S. Bergeson,et al.  Quantitative trait loci influencing morphine antinociception in four mapping populations , 2001, Mammalian Genome.

[4]  M. Festing,et al.  Strain differences in haematological response to chloramphenicol succinate in mice: implications for toxicological research. , 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[5]  F. Gonzalez,et al.  Applications of Genetically Manipulated Mice in Pharmacogenetics and Pharmacogenomics , 2000, Pharmacology.

[6]  A. Roses.  Pharmacogenetics and the practice of medicine , 2000, Nature.

[7]  L. Whitehouse,et al.  Detection of quantitative trait loci affecting caffeine metabolism by interval mapping in a genome-wide scan of C3H/HeJ x APN F(2) mice. , 1999, Drug metabolism and disposition: the biological fate of chemicals.

[8]  M. Relling,et al.  Pharmacogenomics: translating functional genomics into rational therapeutics. , 1999, Science.

[9]  J. Mogil,et al.  Pharmacogenetic variability in neuronal nicotinic receptor-mediated antinociception. , 1999, Pharmacogenetics.

[10]  L. Kruglyak.  Prospects for whole-genome linkage disequilibrium mapping of common disease genes , 1999, Nature Genetics.

[11]  J. Sludden,et al.  Liver Dihydropyrimidine Dehydrogenase Activity in Human, Cynomolgus Monkey, Rhesus Monkey, Dog, Rat and Mouse , 1998, Pharmacology.

[12]  M. Girard,et al.  Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity. , 1997, Pharmacogenetics.

[13]  J. Crabbe,et al.  Quantitative Trait Loci Involved in Genetic Predisposition to Acute Alcohol Withdrawal in Mice , 1997, The Journal of Neuroscience.

[14]  L. Corcos,et al.  Genetic analysis of the phenobarbital regulation of the cytochrome P-450 2b-9 and aldehyde dehydrogenase type 2 mRNAs in mouse liver. , 1996, The Biochemical journal.

[15]  R. Quock,et al.  Nitrous oxide antinociception in BXD recombinant inbred mouse strains and identification of quantitative trait loci , 1996, Brain Research.

[16]  W. E. Woods,et al.  Genetic analysis of sensitization and tolerance to cocaine. , 1994, The Journal of pharmacology and experimental therapeutics.

[17]  J. Kehrer,et al.  Murine strain differences in metabolism and bladder toxicity of cyclophosphamide. , 1992, Toxicology.

[18]  S. Kanekal,et al.  Pharmacokinetics, metabolic activation, and lung toxicity of cyclophosphamide in C57/B16 and ICR mice. , 1992, Toxicology and applied pharmacology.

[19]  A. Darvasi,et al.  Experimental strategies for the genetic dissection of complex traits in animal models , 1998, Nature Genetics.

[20]  J. Ward,et al.  Strain-dependent effects of phenobarbital on liver tumor promotion in inbred mice. , 1990, Progress in clinical and biological research.