The advantages and limitations of trait analysis with GWAS: a review
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[1] Nicholas A. Johnson,et al. Genetic Architecture of Skin and Eye Color in an African-European Admixed Population , 2013, PLoS genetics.
[2] Bjarni J. Vilhjálmsson,et al. The nature of confounding in genome-wide association studies , 2012, Nature Reviews Genetics.
[3] Ronald M. Nelson,et al. SELECTION ON VARIANCE‐CONTROLLING GENES: ADAPTABILITY OR STABILITY , 2012, Evolution; international journal of organic evolution.
[4] Bjarni J. Vilhjálmsson,et al. GWAPP: A Web Application for Genome-Wide Association Mapping in Arabidopsis[W][OA] , 2012, Plant Cell.
[5] Eleazar Eskin,et al. Genome-wide association studies in mice , 2012, Nature Reviews Genetics.
[6] M. Nordborg,et al. Genome-Wide Association Studies Identify Heavy Metal ATPase3 as the Primary Determinant of Natural Variation in Leaf Cadmium in Arabidopsis thaliana , 2012, PLoS genetics.
[7] Jean-Paul Bouchet,et al. Genome-Wide Association Mapping in Tomato (Solanum lycopersicum) Is Possible Using Genome Admixture of Solanum lycopersicum var. cerasiforme , 2012, G3: Genes | Genomes | Genetics.
[8] Bjarni J. Vilhjálmsson,et al. A mixed-model approach for genome-wide association studies of correlated traits in structured populations , 2012, Nature Genetics.
[9] Jonathan P. Beauchamp,et al. The Promises and Pitfalls of Genoeconomics* , 2012, Annual review of economics.
[10] Taesung Park,et al. A novel method to identify high order gene-gene interactions in genome-wide association studies: Gene-based MDR , 2012, BMC Bioinformatics.
[11] Eleazar Eskin,et al. Improved linear mixed models for genome-wide association studies , 2012, Nature Methods.
[12] Bjarni J. Vilhjálmsson,et al. An efficient multi-locus mixed model approach for genome-wide association studies in structured populations , 2012, Nature Genetics.
[13] Holger Schwender,et al. Incorporating Genotype Uncertainties Into the Genotypic TDT for Main Effects and Gene‐Environment Interactions , 2012, Genetic epidemiology.
[14] Julin N. Maloof,et al. A Genome-Wide Association Study Identifies Variants Underlying the Arabidopsis thaliana Shade Avoidance Response , 2012, PLoS genetics.
[15] Ian J. Deary,et al. Genetic contributions to stability and change in intelligence from childhood to old age , 2012, Nature.
[16] Greg Gibson,et al. Rare and common variants: twenty arguments , 2012, Nature Reviews Genetics.
[17] A. Auton,et al. Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel , 2011, Nature Genetics.
[18] Xiaofeng Zhu,et al. Detecting rare variants. , 2012, Methods in molecular biology.
[19] Qian Qian,et al. Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm , 2011, Nature Genetics.
[20] Lindsey J. Leach,et al. Genome-wide association mapping of agronomic and morphologic traits in highly structured populations of barley cultivars , 2012, Theoretical and Applied Genetics.
[21] Detlef Weigel,et al. Natural Variation in Arabidopsis: From Molecular Genetics to Ecological Genomics1[W][OA] , 2011, Plant Physiology.
[22] Yilin Dai,et al. Improved power by collapsing rare and common variants based on a data-adaptive forward selection strategy , 2011, BMC proceedings.
[23] U. Peters,et al. The use of imputed values in the meta‐analysis of genome‐wide association studies , 2011, Genetic epidemiology.
[24] M. Nordborg,et al. A Map of Local Adaptation in Arabidopsis thaliana , 2011, Science.
[25] B. Hayes,et al. Genome-wide association mapping in Norwegian Red cattle identifies quantitative trait loci for fertility and milk production on BTA12. , 2011, Animal genetics.
[26] K. Borgwardt,et al. Whole-genome sequencing of multiple Arabidopsis thaliana populations , 2011, Nature Genetics.
[27] Vipin T. Sreedharan,et al. Multiple reference genomes and transcriptomes for Arabidopsis thaliana , 2011, Nature.
[28] Jason A. Corwin,et al. Combining Genome-Wide Association Mapping and Transcriptional Networks to Identify Novel Genes Controlling Glucosinolates in Arabidopsis thaliana , 2011, PLoS biology.
[29] Jonathan D. G. Jones,et al. Evidence for Network Evolution in an Arabidopsis Interactome Map , 2011, Science.
[30] Karsten M. Borgwardt,et al. Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs , 2011, Bioinform..
[31] Chris S. Haley,et al. EpiGPU: exhaustive pairwise epistasis scans parallelized on consumer level graphics cards , 2011, Bioinform..
[32] Marylyn D. Ritchie,et al. Knowledge-Driven Multi-Locus Analysis Reveals Gene-Gene Interactions Influencing HDL Cholesterol Level in Two Independent EMR-Linked Biobanks , 2011, PloS one.
[33] F. V. van Eeuwijk,et al. Analysis of natural allelic variation in Arabidopsis using a multiparent recombinant inbred line population , 2011, Proceedings of the National Academy of Sciences.
[34] Peter J. Bradbury,et al. Genome-wide association study of leaf architecture in the maize nested association mapping population , 2011, Nature Genetics.
[35] Naomi R. Wray,et al. Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results , 2011, PLoS biology.
[36] Allison M. Louthan,et al. Comparing the adaptive landscape across trait types: larger QTL effect size in traits under biotic selection , 2011, BMC Evolutionary Biology.
[37] Joy Bergelson,et al. Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana , 2010, Nature Reviews Genetics.
[38] Joy Bergelson,et al. Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana , 2010, Proceedings of the National Academy of Sciences.
[39] Eleftheria Zeggini,et al. Rare variant association analysis methods for complex traits. , 2010, Annual review of genetics.
[40] M. Nordborg,et al. Conditions Under Which Genome-Wide Association Studies Will be Positively Misleading , 2010, Genetics.
[41] M. Nordborg,et al. A Coastal Cline in Sodium Accumulation in Arabidopsis thaliana Is Driven by Natural Variation of the Sodium Transporter AtHKT1;1 , 2010, PLoS genetics.
[42] Gaurav Bhatia,et al. A Covering Method for Detecting Genetic Associations between Rare Variants and Common Phenotypes , 2010, PLoS Comput. Biol..
[43] Joy Bergelson,et al. Linkage and Association Mapping of Arabidopsis thaliana Flowering Time in Nature , 2010, PLoS genetics.
[44] Zhiwu Zhang,et al. Mixed linear model approach adapted for genome-wide association studies , 2010, Nature Genetics.
[45] D. Thomas,et al. Gene–environment-wide association studies: emerging approaches , 2010, Nature Reviews Genetics.
[46] David B. Goldstein,et al. Rare Variants Create Synthetic Genome-Wide Associations , 2010, PLoS biology.
[47] Bjarni J. Vilhjálmsson,et al. Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines , 2010 .
[48] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[49] R. Mott,et al. A Multiparent Advanced Generation Inter-Cross to Fine-Map Quantitative Traits in Arabidopsis thaliana , 2009, PLoS genetics.
[50] F. Collins,et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits , 2009, Proceedings of the National Academy of Sciences.
[51] H. Cordell. Detecting gene–gene interactions that underlie human diseases , 2009, Nature Reviews Genetics.
[52] Frank Johannes,et al. Assessing the Impact of Transgenerational Epigenetic Variation on Complex Traits , 2009, PLoS genetics.
[53] Jonathan Flint,et al. Genetic architecture of quantitative traits in mice, flies, and humans. , 2009, Genome research.
[54] Detlef Weigel,et al. QTL Mapping in New Arabidopsis thaliana Advanced Intercross-Recombinant Inbred Lines , 2009, PloS one.
[55] A. Korol,et al. Genetics of phenotypic plasticity: QTL analysis in barley, Hordeum vulgare , 2009, Heredity.
[56] P. Phillips. Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems , 2008, Nature Reviews Genetics.
[57] S. Leal,et al. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. , 2008, American journal of human genetics.
[58] W. Bodmer,et al. Common and rare variants in multifactorial susceptibility to common diseases , 2008, Nature Genetics.
[59] W. G. Hill,et al. Heritability in the genomics era — concepts and misconceptions , 2008, Nature Reviews Genetics.
[60] D. Heckerman,et al. Efficient Control of Population Structure in Model Organism Association Mapping , 2008, Genetics.
[61] Snæbjörn Pálsson,et al. Genetic determinants of hair, eye and skin pigmentation in Europeans , 2007, Nature Genetics.
[62] Detlef Weigel,et al. Recombination and linkage disequilibrium in Arabidopsis thaliana , 2007, Nature Genetics.
[63] M. Purugganan,et al. The Genetic Architecture of Shoot Branching in Arabidopsis thaliana: A Comparative Assessment of Candidate Gene Associations vs. Quantitative Trait Locus Mapping , 2007, Genetics.
[64] Keyan Zhao,et al. An Arabidopsis Example of Association Mapping in Structured Samples , 2006, PLoS genetics.
[65] M. McMullen,et al. A unified mixed-model method for association mapping that accounts for multiple levels of relatedness , 2006, Nature Genetics.
[66] D. Hunter. Gene–environment interactions in human diseases , 2005, Nature Reviews Genetics.
[67] P. Donnelly,et al. Genome-wide strategies for detecting multiple loci that influence complex diseases , 2005, Nature Genetics.
[68] M. Daly,et al. Genome-wide association studies for common diseases and complex traits , 2005, Nature Reviews Genetics.
[69] James K. M. Brown,et al. QTL analysis of flowering time inArabidopsis thaliana , 1995, Molecular and General Genetics MGG.
[70] M. Koornneef,et al. Naturally occurring genetic variation in Arabidopsis thaliana. , 2004, Annual review of plant biology.
[71] A. Paterson,et al. QTL mapping of naturally-occurring variation in flowering time of Arabidopsis thaliana , 1994, Molecular and General Genetics MGG.
[72] Justin O Borevitz,et al. The Impact of Genomics on the Study of Natural Variation in Arabidopsis , 2003, Plant Physiology.
[73] G. Coupland,et al. Analysis of natural allelic variation at flowering time loci in the Landsberg erecta and Cape Verde Islands ecotypes of Arabidopsis thaliana. , 1998, Genetics.