Antioxidants, but not B-group vitamins increase the resistance of low-density lipoprotein to oxidation: a randomized, factorial design, placebo-controlled trial.

[1]  S. Grundy,et al.  Effect of ascorbate supplementation on low density lipoprotein oxidation in smokers. , 1996, Atherosclerosis.

[2]  J. Fruchart,et al.  Detection of autoantibodies against oxidized low-density lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease. , 1995, Clinica chimica acta; international journal of clinical chemistry.

[3]  J. Vuilleumier,et al.  Fluorometric assay of vitamin C in biological materials using a centrifugal analyser with fluorescence attachment , 1989 .

[4]  K. Gey.  Ten-year retrospective on the antioxidant hypothesis of arteriosclerosis: Threshold plasma levels of antioxidant micronutrients related to minimum cardiovascular risk , 1995 .

[5]  S. Grundy,et al.  β-Carotene inhibits the oxidative modification of low-density lipoprotein , 1991 .

[6]  J L Witztum,et al.  Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. , 1989, The New England journal of medicine.

[7]  A. Sevanian,et al.  Copper can promote oxidation of LDL by markedly different mechanisms. , 1998, Free radical biology & medicine.

[8]  G. Bondjers,et al.  Uptake and degradation of low density lipoproteins in atherosclerotic rabbit aorta: role of local LDL modification. , 1991, Journal of lipid research.

[9]  W Y Craig,et al.  ELISA of IgG antibody to oxidized low-density lipoprotein: effects of blocking buffer and method of data expression. , 1994, Clinical chemistry.

[10]  J. G. Bieri,et al.  Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography. , 1983, Clinical chemistry.

[11]  S. Devaraj,et al.  Low-density lipoprotein oxidation, antioxidants, and atherosclerosis: a clinical biochemistry perspective. , 1996, Clinical chemistry.

[12]  J. Keaney,et al.  Antioxidants and atherosclerotic heart disease. , 1997, The New England journal of medicine.

[13]  J. Graaf,et al.  LDL oxidation and coronary atherosclerosis , 1992, The Lancet.

[14]  K. Meeter,et al.  Estrogen replacement decreases the level of antibodies against oxidized low-density lipoprotein in postmenopausal women with coronary heart disease. , 1998, Metabolism: clinical and experimental.

[15]  J. Keaney,et al.  Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation. , 1995, The Journal of clinical investigation.

[16]  D. Thurnham,et al.  Concurrent liquid-chromatographic assay of retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in plasma, with tocopherol acetate as internal standard. , 1988, Clinical chemistry.

[17]  D. Brown,et al.  Serum antibodies to oxidized low-density lipoprotein and ceroid in chronic periaortitis. , 1990, Archives of pathology & laboratory medicine.

[18]  C. Drevon,et al.  Effect of homocysteine on copper ion-catalyzed, azo compound-initiated, and mononuclear cell-mediated oxidative modification of low density lipoprotein. , 1996, Journal of lipid research.

[19]  S. Grundy,et al.  Effect of combined supplementation with alpha-tocopherol, ascorbate, and beta carotene on low-density lipoprotein oxidation. , 1993, Circulation.

[20]  S. Nattel,et al.  Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group. , 1997, The New England journal of medicine.

[21]  E. Erdmann,et al.  Increased oxidation of LDL in patients with coronary artery disease is independent from dietary vitamins E and C. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[22]  H. Stähelin,et al.  Vitamin E and vitamin A concentrations in plasma adjusted for cholesterol and triglycerides by multiple regression. , 1995, Clinical chemistry.

[23]  S. Rankin,et al.  α-tocopherol consumption during low-density-lipoprotein oxidation , 1990 .

[24]  A. Hamsten,et al.  Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man , 1992, The Lancet.

[25]  A. Evans,et al.  Effect of B-group vitamins and antioxidant vitamins on hyperhomocysteinemia: a double-blind, randomized, factorial-design, controlled trial. , 1998, The American journal of clinical nutrition.

[26]  R. Stocker,et al.  Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein , 1993 .

[27]  L. Packer,et al.  Recycling of vitamin E in human low density lipoproteins. , 1992, Journal of lipid research.

[28]  M. Lopes-Virella,et al.  Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers , 1993, International journal of clinical & laboratory research.

[29]  S. Parthasarathy.  Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor. , 1987, Biochimica et biophysica acta.

[30]  G. Finardi,et al.  Specificity of autoantibodies against oxidized LDL as an additional marker for atherosclerotic risk. , 1993, Coronary artery disease.

[31]  E. Rimm,et al.  Vitamin E consumption and the risk of coronary heart disease in men. , 1993, The New England journal of medicine.

[32]  J. Loscalzo,et al.  Low-Dose α-Tocopherol Improves and High-Dose α- Tocopherol Worsens Endothelial Vasodilator Function in Cholesterol-Fed Rabbits , 1994 .

[33]  G. Bellomo,et al.  Autoantibodies Against Oxidatively Modified Low-Density Lipoproteins in NIDDM , 1995, Diabetes.

[34]  W. Klein,et al.  Autoantibodies to oxidized low density lipoproteins in restenosis following coronary angioplasty. , 1994, Cardiology.

[35]  I. Mcdowell,et al.  A Rapid Method for Measurement of the Susceptibility to Oxidation of Low-Density Lipoprotein , 1995, Annals of clinical biochemistry.

[36]  J. Manson,et al.  13 – Natural Antioxidants and Cardiovascular Disease: Observational Epidemiologic Studies and Randomized Trials , 1994 .

[37]  P. Demacker,et al.  Vitamin E and fatty acid intervention does not attenuate the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[38]  G. Starkebaum,et al.  Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. , 1986, The Journal of clinical investigation.

[39]  J. Loscalzo,et al.  Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits. , 1994, The Journal of clinical investigation.

[40]  A. Chait,et al.  The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells. , 1987, The Journal of biological chemistry.

[41]  G. Omenn,et al.  Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. , 1996, The New England journal of medicine.

[42]  J. Morrow,et al.  Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. , 1994, The Journal of clinical investigation.

[43]  J. Morrow,et al.  Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. , 1995, The New England journal of medicine.

[44]  D. Albanes,et al.  The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. , 1994, The New England journal of medicine.

[45]  F. Kelly,et al.  Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) , 1996, The Lancet.

[46]  M. Reilly,et al.  Modulation of oxidant stress in vivo in chronic cigarette smokers. , 1996, Circulation.

[47]  T. Reynolds,et al.  A Simple Internally-Standardised Isocratic HPLC Assay for Vitamin B6 in Human Serum , 1992 .

[48]  J. Salonen,et al.  Autoantibody against oxidised LDL and progression of carotid atherosclerosis , 1992, The Lancet.

[49]  J. Manson,et al.  Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. , 1996, The New England journal of medicine.

[50]  W. Vermaak,et al.  Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. , 1993, The American journal of clinical nutrition.

[51]  P. Puska,et al.  Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. , 1991, The American journal of clinical nutrition.

[52]  J. Manson,et al.  A secondary prevention trial of antioxidant vitamins and cardiovascular disease in women. Rationale, design, and methods. The WACS Research Group. , 1995, Annals of epidemiology.

[53]  G. Omenn,et al.  A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. , 1995, JAMA.

[54]  P. Baghurst,et al.  Antioxidant vitamins and low-density-lipoprotein oxidation. , 1993, The American journal of clinical nutrition.

[55]  J. Ubbink,et al.  Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum. , 1991, Journal of chromatography.

[56]  G. Schonfeld,et al.  Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits. , 1995, The Journal of clinical investigation.

[57]  C. Hennekens.  Antioxidant vitamins and cardiovascular disease: current perspectives and future directions. , 1997, European heart journal.

[58]  V. Armstrong,et al.  Serum antibodies to oxidised low-density lipoprotein in pre-eclampsia and coronary heart disease , 1994, The Lancet.

[59]  M. Brown,et al.  A Randomised Controlled Trial of Vitamin E in Patients with Coronary Disease: The Cambridge Heart Antioxidant Study (CHAOS) , 1996 .

[60]  A. Ooshima,et al.  Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. , 1987, Proceedings of the National Academy of Sciences of the United States of America.