A Unified Approach to Wearable Ballistocardiogram Gating and Wave Localization

OBJECTIVE Toward the ultimate goal of cuff-less blood pressure (BP) trend tracking via pulse transit time (PTT) using wearable ballistocardiogram (BCG) signals, we present a unified approach to the gating of wearable BCG and the localization of wearable BCG waves. METHODS We present a unified approach to localize wearable BCG waves suited to various gating and localization reference signals. Our approach gates individual wearable BCG beats and identifies candidate waves in each wearable BCG beat using a fiducial point in a reference signal, and exploits a pre-specified probability distribution of the time interval between the BCG wave and the fiducial point in the reference signal to accurately localize the wave in each wearable BCG beat. We tested the validity of our approach using experimental data collected from 17 healthy volunteers. RESULTS We showed that our approach could localize the J wave in the wearable wrist BCG accurately with both the electrocardiogram (ECG) and the wearable wrist photoplethysmogram (PPG) signals as reference, and that the wrist BCG-PPG PTT thus derived exhibited high correlation to BP. CONCLUSION We demonstrated the proof-of-concept of a unified approach to localize wearable BCG waves suited to various gating and localization reference signals compatible with wearable measurement. SIGNIFICANCE Prior work using the BCG itself or the ECG to gate the BCG beats and localize the waves to compute PTT are not ideally suited to the wearable BCG. Our approach may foster the development of cuff-less BP monitoring technologies based on the wearable BCG.

[1]  Omer T. Inan,et al.  Ballistocardiogram: Mechanism and Potential for Unobtrusive Cardiovascular Health Monitoring , 2016, Scientific Reports.

[2]  Omer T. Inan,et al.  Ballistocardiogram-Based Approach to Cuffless Blood Pressure Monitoring: Proof of Concept and Potential Challenges , 2018, IEEE Transactions on Biomedical Engineering.

[3]  M. Elgendi On the Analysis of Fingertip Photoplethysmogram Signals , 2012, Current cardiology reviews.

[4]  Sayup Kim,et al.  A Chair-Based Unconstrained/Nonintrusive Cuffless Blood Pressure Monitoring System Using a Two-Channel Ballistocardiogram , 2019, Sensors.

[5]  Ramakrishna Mukkamala,et al.  PPG Sensor Contact Pressure Should Be Taken Into Account for Cuff-Less Blood Pressure Measurement , 2020, IEEE Transactions on Biomedical Engineering.

[6]  Richard M. Wiard,et al.  Robust ballistocardiogram acquisition for home monitoring , 2009, Physiological measurement.

[7]  D. Jeong,et al.  Slow-wave sleep estimation on a load-cell-installed bed: a non-constrained method , 2009, Physiological measurement.

[8]  Omer T. Inan,et al.  SeismoWatch , 2017, Proc. ACM Interact. Mob. Wearable Ubiquitous Technol..

[9]  Dae-Geun Jang,et al.  The Potential of Wearable Limb Ballistocardiogram in Blood Pressure Monitoring via Pulse Transit Time , 2019, Scientific Reports.

[10]  Roozbeh Jafari,et al.  BioWatch: A Noninvasive Wrist-Based Blood Pressure Monitor That Incorporates Training Techniques for Posture and Subject Variability , 2016, IEEE Journal of Biomedical and Health Informatics.

[11]  Hee Chan Kim,et al.  A Wrist-Worn Integrated Health Monitoring Instrument with a Tele-Reporting Device for Telemedicine and Telecare , 2006, IEEE Transactions on Instrumentation and Measurement.

[12]  Roozbeh Jafari,et al.  Noninvasive Cuffless Blood Pressure Estimation Using Pulse Transit Time and Impedance Plethysmography , 2019, IEEE Transactions on Biomedical Engineering.

[13]  Lisheng Xu,et al.  Unobtrusive Estimation of Cardiovascular Parameters with Limb Ballistocardiography , 2019, Italian National Conference on Sensors.

[14]  Youn Ho Kim,et al.  Physiological Association between Limb Ballistocardiogram and Arterial Blood Pressure Waveforms: A Mathematical Model-Based Analysis , 2019, Scientific Reports.

[15]  Chiyul Yoon,et al.  Ferroelectret film-based patch-type sensor for continuous blood pressure monitoring , 2014 .

[16]  Shuvo Roy,et al.  Toward Continuous, Noninvasive Assessment of Ventricular Function and Hemodynamics: Wearable Ballistocardiography , 2015, IEEE Journal of Biomedical and Health Informatics.

[17]  P. Migeotte,et al.  Modification of the mechanical cardiac performance during end-expiratory voluntary apnea recorded with ballistocardiography and seismocardiography , 2019, Physiological measurement.

[18]  Marjorie Skubic,et al.  Monitoring the Relative Blood Pressure Using a Hydraulic Bed Sensor System , 2019, IEEE Transactions on Biomedical Engineering.

[19]  Survi Kyal,et al.  Toward Ubiquitous Blood Pressure Monitoring via Pulse Transit Time: Theory and Practice , 2015, IEEE Transactions on Biomedical Engineering.

[20]  Roozbeh Jafari,et al.  Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art , 2019, IEEE Transactions on Biomedical Circuits and Systems.

[21]  Mingshan Sun,et al.  Optical blood pressure estimation with photoplethysmography and FFT-based neural networks. , 2016, Biomedical optics express.

[22]  Dae-Geun Jang,et al.  Data mining investigation of the association between a limb ballistocardiogram and blood pressure , 2018, Physiological measurement.

[23]  J. Hahn,et al.  Smartphone-based blood pressure monitoring via the oscillometric finger-pressing method , 2018, Science Translational Medicine.

[24]  I STARR,et al.  The Effect of Aging and of the Development of Disease on the Ballistocardiogram: A Study of Eighty Subjects, Originally Healthy, Followed from Ten to Fourteen Years , 1952, Circulation.

[25]  Takahiro Okumura,et al.  Development and Validation of a Novel Cuff-Less Blood Pressure Monitoring Device , 2017, JACC. Basic to translational science.

[26]  Marjorie Skubic,et al.  Cardiovascular Function and Ballistocardiogram: A Relationship Interpreted via Mathematical Modeling , 2018, IEEE Transactions on Biomedical Engineering.