From genetics to biology: advancing mental health research in the Genomics ERA
暂无分享,去创建一个
A. Addington | F. McMahon | K. Merikangas | S. Koester | T. Lehner | L. Brady | G. Senthil | D. Panchision | David M. Panchision | Miri Gitik | D. Meinecke | P. Alexander Arguello | Susan E. Borja | Tara Dutka
[1] John P. Rice,et al. Identification of common genetic risk variants for autism spectrum disorder , 2019, Nature Genetics.
[2] Annie W Shieh,et al. Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder , 2018, Science.
[3] Matthew W. Mosconi,et al. Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk , 2018, bioRxiv.
[4] Alicia R. Martin,et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder , 2018, Nature Genetics.
[5] V. Anttila,et al. Analysis of shared heritability in common disorders of the brain , 2018, Science.
[6] P. Visscher,et al. Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model , 2018, Cell.
[7] D. Schaid,et al. From genome-wide associations to candidate causal variants by statistical fine-mapping , 2018, Nature Reviews Genetics.
[8] Chandra L. Theesfeld,et al. Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk , 2018, Nature Genetics.
[9] Caroline F. Wright,et al. Common genetic variants contribute to risk of rare severe neurodevelopmental disorders , 2018, Nature.
[10] Ryan L. Collins,et al. An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder , 2018, Nature Genetics.
[11] Jakob Grove,et al. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection , 2018, Nature Genetics.
[12] S. Hyman,et al. The daunting polygenicity of mental illness: making a new map , 2018, Philosophical Transactions of the Royal Society B: Biological Sciences.
[13] Warren W. Kretzschmar,et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression , 2017, Nature Genetics.
[14] P. Visscher,et al. 10 Years of GWAS Discovery: Biology, Function, and Translation. , 2017, American journal of human genetics.
[15] Gerome Breen,et al. Genetic identification of brain cell types underlying schizophrenia , 2017, Nature Genetics.
[16] Sharyn A. Lincoln,et al. FORWARD: A Registry and Longitudinal Clinical Database to Study Fragile X Syndrome , 2017, Pediatrics.
[17] T. Werge,et al. Risk of Psychiatric Disorders Among Individuals With the 22q11.2 Deletion or Duplication: A Danish Nationwide, Register-Based Study , 2017, JAMA psychiatry.
[18] Joan,et al. Prevalence and architecture of de novo mutations in developmental disorders , 2017, Nature.
[19] John P. A. Ioannidis,et al. A manifesto for reproducible science , 2017, Nature Human Behaviour.
[20] Stephan J Sanders,et al. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders , 2016, Nature Genetics.
[21] Wei Cheng,et al. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects , 2016, Nature Genetics.
[22] Giulio Genovese,et al. Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia , 2016, Nature Neuroscience.
[23] A. Price,et al. Dissecting the genetics of complex traits using summary association statistics , 2016, Nature Reviews Genetics.
[24] Chandra L. Theesfeld,et al. Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder , 2016, Nature Neuroscience.
[25] Stephan J Sanders,et al. Refining the role of de novo protein truncating variants in neurodevelopmental disorders using population reference samples , 2016, Nature Genetics.
[26] Minna Männikkö,et al. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders , 2016, Nature Neuroscience.
[27] Christopher S. Poultney,et al. Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci , 2015, Neuron.
[28] Stephan J Sanders,et al. A framework for the interpretation of de novo mutation in human disease , 2014, Nature Genetics.
[29] D. G. MacArthur,et al. Guidelines for investigating causality of sequence variants in human disease , 2014, Nature.
[30] Adam J. Schwarz,et al. CNVs conferring risk of autism or schizophrenia affect cognition in controls , 2013, Nature.
[31] Daniel F. Gudbjartsson,et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease , 2008, Nature.