Convolutional Neural Networks based classification of breast ultrasonography images by hybrid method with respect to benign, malignant, and normal using mRMR

Early diagnosis of breast lesions and differentiation of malignant lesions from benign lesions are important for the prognosis of breast cancer. In the diagnosis of this disease ultrasound is an extremely important radiological imaging method because it enables biopsy as well as lesion characterization. Since ultrasonographic diagnosis depends on the expert, the knowledge level and experience of the user is very important. In addition, the contribution of computer aided systems is quite high, as these systems can reduce the workload of radiologists and reinforce their knowledge and experience when considered together with a dense patient population in hospital conditions. In this paper, a hybrid based CNN system is developed for diagnosing breast cancer lesions with respect to benign, malignant and normal. Alexnet, MobilenetV2, and Resnet50 models are used as the base for the Hybrid structure. The features of these models used are obtained and concatenated separately. Thus, the number of features used are increased. Later, the most valuable of these features are selected by the mRMR (Minimum Redundancy Maximum Relevance) feature selection method and classified with machine learning classifiers such as SVM, KNN. The highest rate is obtained in the SVM classifier with 95.6% in accuracy.

[1]  Yudong Zhang,et al.  A classification method for brain MRI via MobileNet and feedforward network with random weights , 2020, Pattern Recognit. Lett..

[2]  Fabio Tozeto Ramos,et al.  Malicious Software Classification Using Transfer Learning of ResNet-50 Deep Neural Network , 2017, 2017 16th IEEE International Conference on Machine Learning and Applications (ICMLA).

[3]  Walid Al-Dhabyani,et al.  Dataset of breast ultrasound images , 2019, Data in brief.

[4]  F J Gilbert,et al.  Artificial intelligence in breast imaging. , 2019, Clinical radiology.

[5]  Ling Zhang,et al.  Automated breast cancer detection and classification using ultrasound images: A survey , 2015, Pattern Recognit..

[6]  Ukihide Tateishi,et al.  Detection and Diagnosis of Breast Cancer Using Artificial Intelligence Based Assessment of Maximum Intensity Projection Dynamic Contrast-Enhanced Magnetic Resonance Images , 2020, Diagnostics.

[7]  Anjan Gudigar,et al.  Development of breast papillary index for differentiation of benign and malignant lesions using ultrasound images , 2020, Journal of Ambient Intelligence and Humanized Computing.

[8]  Fuhui Long,et al.  Feature selection based on mutual information criteria of max-dependency, max-relevance, and min-redundancy , 2003, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[9]  W. Cheng,et al.  Evaluating the Accuracy of Breast Cancer and Molecular Subtype Diagnosis by Ultrasound Image Deep Learning Model , 2021, Frontiers in Oncology.

[10]  T. Helbich,et al.  Probably benign breast masses at US: is follow-up an acceptable alternative to biopsy? , 2007, Radiology.

[11]  U. Rajendra Acharya,et al.  Accurate deep neural network model to detect cardiac arrhythmia on more than 10,000 individual subject ECG records , 2020, Computer Methods and Programs in Biomedicine.

[12]  W. Moon,et al.  Comparison of Abbreviated MRI and Full Diagnostic MRI in Distinguishing between Benign and Malignant Lesions Detected by Breast MRI: A Multireader Study , 2020, Korean journal of radiology.

[13]  Polen Taşıyan Bal Arılarının MobileNetV2 Mimarisi ile Sınıflandırılması , 2021 .

[14]  X. Cui,et al.  Artificial intelligence in breast ultrasound , 2019, World journal of radiology.

[15]  Ahmet Çinar,et al.  A Deep Learning Based Hybrid Approach for COVID-19 Disease Detections , 2020, Traitement du Signal.

[16]  W. Mayo-Smith,et al.  Characterization of Breast Masses With Sonography , 2005, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[17]  Liang Huang,et al.  Celiac disease diagnosis from videocapsule endoscopy images with residual learning and deep feature extraction , 2019, Comput. Methods Programs Biomed..

[18]  J. Choi,et al.  Deep learning-based computer-aided diagnosis in screening breast ultrasound to reduce false-positive diagnoses , 2021, Scientific Reports.

[19]  W. Moon,et al.  Automated Breast Ultrasound Screening for Dense Breasts , 2019, Korean journal of radiology.

[20]  M. Ben-David,et al.  Contrast-enhanced spectral mammography (CESM) in women presenting with palpable breast findings. , 2020, Clinical imaging.

[21]  Deepa Sheth,et al.  Artificial intelligence in the interpretation of breast cancer on MRI , 2019, Journal of magnetic resonance imaging : JMRI.

[22]  Lahcen Koutti,et al.  MultiD-CNN: A multi-dimensional feature learning approach based on deep convolutional networks for gesture recognition in RGB-D image sequences , 2020, Expert Syst. Appl..

[23]  Minping Jia,et al.  Intelligent fault diagnosis of rotating machinery using improved multiscale dispersion entropy and mRMR feature selection , 2019, Knowl. Based Syst..

[24]  Lin Han,et al.  Diagnostic Efficiency of the Breast Ultrasound Computer-Aided Prediction Model Based on Convolutional Neural Network in Breast Cancer , 2020, Journal of Digital Imaging.

[25]  Ruey-Feng Chang,et al.  Computer-aided diagnosis of breast ultrasound images using ensemble learning from convolutional neural networks , 2020, Comput. Methods Programs Biomed..

[26]  Krzysztof J. Geras,et al.  Artificial Intelligence for Mammography and Digital Breast Tomosynthesis: Current Concepts and Future Perspectives. , 2019, Radiology.

[27]  R. Chugh,et al.  Nonlinear approximation of multiplicative inverse quartic functional equation in intuitionistic fuzzy normed spaces , 2021 .

[28]  Rebecca L. Siegel Mph,et al.  Cancer statistics, 2018 , 2018 .

[29]  T. Shanthi,et al.  Automatic diagnosis of skin diseases using convolution neural network , 2020, Microprocess. Microsystems.

[30]  Anjan Gudigar,et al.  Local Preserving Class Separation Framework to Identify Gestational Diabetes Mellitus Mother Using Ultrasound Fetal Cardiac Image , 2020, IEEE Access.

[31]  Ceyhun Yildiz,et al.  An improved residual-based convolutional neural network for very short-term wind power forecasting , 2021 .

[32]  Mesut Toğaçar,et al.  Intelligent skin cancer detection applying autoencoder, MobileNetV2 and spiking neural networks , 2021 .

[33]  Ruey-Feng Chang,et al.  Computer-aided tumor detection in automated breast ultrasound using a 3-D convolutional neural network , 2020, Comput. Methods Programs Biomed..

[34]  U. Rajendra Acharya,et al.  Classification of heart sound signals using a novel deep WaveNet model , 2020, Comput. Methods Programs Biomed..

[35]  T. Endo,et al.  Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial , 2016, The Lancet.

[36]  Thomas Blaschke,et al.  The rise of deep learning in drug discovery. , 2018, Drug discovery today.

[37]  Peyman Hosseinzadeh Kassani,et al.  A comparative study of deep learning architectures on melanoma detection. , 2019, Tissue & cell.

[38]  Yuanshen Zhao,et al.  Deep Learning vs. Radiomics for Predicting Axillary Lymph Node Metastasis of Breast Cancer Using Ultrasound Images: Don't Forget the Peritumoral Region , 2020, Frontiers in Oncology.

[39]  Ahmet Çinar,et al.  Detection of tumors on brain MRI images using the hybrid convolutional neural network architecture. , 2020, Medical hypotheses.

[40]  W. Moon,et al.  Automated Breast Ultrasound System for Breast Cancer Evaluation: Diagnostic Performance of the Two-View Scan Technique in Women with Small Breasts , 2019, Korean journal of radiology.

[41]  Madhavi Raghu,et al.  The Role of Ultrasound in Breast Cancer Screening: The Case for and Against Ultrasound. , 2018, Seminars in ultrasound, CT, and MR.

[42]  Subbhuraam Vinitha Sree,et al.  A novel machine learning framework for automated detection of arrhythmias in ECG segments , 2021, Journal of Ambient Intelligence and Humanized Computing.

[43]  Anat Kornecki,et al.  Current Status of Breast Ultrasound , 2011, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes.