Biaxial stress-strain properties of canine pericardium.

Interpretation of the material properties of biological tissues under biaxial loading conditions has been hampered by wide variability in the coefficients. This variability has been attributed to experimental noise, numerical instability of the fitting algorithms, or to history dependence of the tissue. We have recently described quantitative methods for addressing some of these difficulties in interpretation. This study describes the application of these methods to anterior sheets of mongrel canine pericardium studied in vitro. Each specimen was stretched biaxially with three different combinations of strains and the resulting stress-strain relationships were fitted with a 5-parameter pseudo strain-energy function. Results show that each specimen is highly nonlinear, anisotropic, and history dependent. In addition there was wide inter-specimen variability in the material coefficients. In some cases the direction of the anisotropy was also history dependent. Possible explanations for this unexpected behaviour are discussed.

[1]  S. Rabkin,et al.  Mechanical properties of the isolated canine pericardium. , 1974, Journal of applied physiology.

[2]  G L Freeman,et al.  Pericardial Adaptations during Chronic Cardiac Dilation in Dogs , 1984, Circulation research.

[3]  H. Demiray.  A note on the elasticity of soft biological tissues. , 1972, Journal of biomechanics.

[4]  R N Vaishnav,et al.  Nonlinear anisotropic elastic properties of the canine aorta. , 1972, Biophysical journal.

[5]  Bronson Fh.  The adaptability of the house mouse. , 1984 .

[6]  J S Janicki,et al.  The pericardium and ventricular interaction, distensibility, and function. , 1980, The American journal of physiology.

[7]  Y. Fung,et al.  Biorheology of soft tissues. , 1973, Biorheology.

[8]  M. LeWinter,et al.  Influence of the Pericardium on Left Ventricular End‐ Diastolic Pressure‐Segment Relations during Early and Later Stages of Experimental Chronic Volume Overload in Dogs , 1982, Circulation research.

[9]  M. Morton,et al.  Left ventricular pressure-volume relations shift to the left after long-term loss of pericardial restraint. , 1983, Circulation.

[10]  B. Efron.  Computers and the Theory of Statistics: Thinking the Unthinkable , 1979 .

[11]  A. Hudetz.  Incremental elastic modulus for orthotropic incompressible arteries. , 1979, Journal of biomechanics.

[12]  I. Mirsky,et al.  The Effects of Geometry, Elasticity, and External Pressures on the Diastolic Pressure‐Volume and Stiffness‐Stress Relations: How Important is the Pericardium? , 1979, Circulation research.

[13]  I. Mirsky.  Effects of external pressures on the pressure-volume relation of the left ventricle. , 1978, Bulletin of mathematical biology.

[14]  P. Diaconis,et al.  Computer-Intensive Methods in Statistics , 1983 .

[15]  J S Janicki,et al.  Factors influencing the diastolic pressure-volume relation of the cardiac ventricles. , 1980, Federation proceedings.

[16]  R. N. Vaishnav,et al.  Mathematical characterization of the nonlinear thermorheological behavior of the vascular tissue. , 1982, Biorheology.

[17]  S L Zeger,et al.  An approach to quantification of biaxial tissue stress-strain data. , 1986, Journal of biomechanics.

[18]  F. Yin,et al.  Passive biaxial mechanical properties of isolated canine myocardium. , 1983, The Journal of physiology.

[19]  A. Wiegner,et al.  Mechanical and Structural Correlates of Canine Pericardium , 1981, Circulation research.

[20]  P. H. Dehoff,et al.  On the nonlinear viscoelastic behavior of soft biological tissues. , 1978, Journal of biomechanics.

[21]  A. Shoukas,et al.  The Effect of Right Ventricular Filling on the Pressure‐Volume Relationship of the Ejecting Canine Left Ventricle , 1981, Circulation Research.

[22]  Y. Fung,et al.  The stress-strain relationship for the skin. , 1976, Journal of biomechanics.

[23]  J. S. Janicki,et al.  Dynamic Anisotropic Viscoelastic Properties of the Aorta in Living Dogs , 1973, Circulation research.

[24]  R P Vito,et al.  The role of the pericardium in cardiac mechanics. , 1979, Journal of biomechanics.

[25]  Y Lanir,et al.  Two-dimensional mechanical properties of rabbit skin. II. Experimental results. , 1974, Journal of Biomechanics.

[26]  S W Rabkin,et al.  Mathematical and mechanical modeling of stress-strain relationship of pericardium. , 1975, The American journal of physiology.

[27]  Frank C. P. Yin,et al.  A Video-Dimension Analyzer , 1972 .

[28]  Pin Tong,et al.  Stress and Strain in the Lung , 1978 .

[29]  S A Glantz,et al.  The Pericardium Substantially Affects the Left Ventricular Diastolic Pressure‐Volume Relationship in the Dog , 1978, Circulation research.

[30]  S. Sarnoff,et al.  Ventricular Function: Role of the Pericardium in Regulation of Cardiovascular Hemodynamics , 1955, Circulation research.

[31]  S. Glantz,et al.  Effects of the Pericardium on Left Ventricular Performance , 1980 .

[32]  W. Gaasch,et al.  Pericardial Modulation of Right and Left Ventricular Diastolic Interaction , 1981, Circulation research.

[33]  Y. Fung,et al.  Pseudoelasticity of arteries and the choice of its mathematical expression. , 1979, The American journal of physiology.

[34]  P. Dobrin,et al.  Finite deformation analysis of the relaxed and contracted dog carotid artery. , 1971, Microvascular research.

[35]  H. Spotnitz,et al.  The effect of the pericardium on pressure-volume relations in the canine left ventricle. , 1971, The Journal of surgical research.

[36]  V. Bhargava,et al.  Alteration of the Left Ventricular Diastolic Pressure-Segment Length Relation Produced by the Pericardium: Effects of Cardiac Distension and Afterload Reduction in Conscious Dogs , 1978, Circulation.