Effect of xylitol on dental caries and salivary Streptococcus mutans levels among a group of mother-child pairs.

UNLABELLED Recent researches have focused on xylitol as convenient and effective method to inhibit cariogenic bacteria. The purpose of the present study is to assess the effect of xylitol on plaque accumulation, caries activity and salivary Streptococcus Mutans in a group of Saudi mother-child pairs. MATERIALS AND METHODS The study sample included 60 mother and child pairs selected on the basis of having high salivary streptococcus mutans levels. The study sample was randomly divided into experimental group (30 pairs) and control group (30 pairs). The experimental group was given xylitol treatment and the controls received fluoride varnish. Both groups were examined to assess caries, plaque and salivary streptococcus mutans levels. Xylitol treatment in the form of chewing gum for mothers and tablets for children was consumed three times/day for three months. All subjects received oral hygiene instructions, dietary counseling and restorative treatment. The results showed that the number of mothers and children with high streptococcus levels in the experimental group decreased to a statistically significant level at the end of the three month period, similarly, the control mothers showed the same trend. A statistically significant decrease in plaque scores was evident only among the children S experimental group. The caries level of children and mothers showed no statistically significant differences between the experimental and control groups. The factors which significantly affected the streptococcus mutans count in children after three months were the child' dmft at baseline the preventive method used and the mother'salivary streptococcus mutans level.

[1]  P. Milgrom,et al.  Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial [ISRCTN43479664] , 2006, BMC Oral Health.

[2]  B. Burt The use of sorbitol- and xylitol-sweetened chewing gum in caries control. , 2006, Journal of the American Dental Association.

[3]  P. Milgrom,et al.  Mutans Streptococci Dose Response to Xylitol Chewing Gum , 2006, Journal of dental research.

[4]  C. Hayes,et al.  The effect of non-cariogenic sweeteners on the prevention of dental caries: a review of the evidence. , 2001, Journal of dental education.

[5]  K. Pienihäkkinen,et al.  Influence of Maternal Xylitol Consumption on Mother–Child Transmission of Mutans Streptococci: 6–Year Follow–Up , 2001, Caries Research.

[6]  G. Campus,et al.  Caries experience and streptococci and lactobacilli salivary levels in 6-8-year-old Sardinians. , 2008, International journal of paediatric dentistry.

[7]  Y. Yamamoto,et al.  Xylitol-induced elevated expression of the gbpC gene in a population of Streptococcus mutans cells. , 2000, European journal of oral sciences.

[8]  P. Alanen,et al.  Occurrence of Dental Decay in Children after Maternal Consumption of Xylitol Chewing Gum, a Follow-up from 0 to 5 Years of Age , 2000, Journal of dental research.

[9]  K. Pienihäkkinen,et al.  Influence of Maternal Xylitol Consumption on Acquisition of Mutans Streptococci by Infants , 2000, Journal of dental research.

[10]  K. Isotupa,et al.  The Optimum Time to Initiate Habitual Xylitol Gum-chewing for Obtaining Long-term Caries Prevention , 1999, Journal of dental research.

[11]  K. Isotupa,et al.  Physical, chemical, and histologic changes in dentin caries lesions of primary teeth induced by regular use of polyol chewing gums. , 1998, Acta odontologica Scandinavica.

[12]  N. Salako,et al.  Caries experience of children aged 6-9 years in Jeddah, Saudi Arabia. , 2009, International journal of paediatric dentistry.

[13]  K. Isotupa,et al.  Xylitol Chewing Gums and Caries Rates: A 40-month Cohort Study , 1995, Journal of dental research.

[14]  Tanzer Jm Xylitol chewing gum and dental caries. , 1995 .

[15]  K. Isotupa,et al.  Stabilisation of rampant caries: polyol gums and arrest of dentine caries in two long-term cohort studies in young subjects. , 1995, International dental journal.

[16]  N. Salako,et al.  PREVALENCE AND DISTRIBUTION OF CARIES IN THE PRIMARY DENTITION IN A COSMOPOLITAN SAUDI POPULATION , 1995 .

[17]  G. Cutter,et al.  Initial Acquisition of Mutans Streptococci by Infants: Evidence for a Discrete Window of Infectivity , 1993, Journal of dental research.

[18]  P. Alanen,et al.  Long-term effect of xylitol chewing gum in the prevention of dental caries: a follow-up 5 years after termination of a prevention program. , 1993, Caries research.

[19]  J. S. van der Hoeven,et al.  Effects of Fluoride and Chlorhexidine on the Microflora of Dental Root Surfaces and Progression of Root-surface Caries , 1991, Journal of dental research.

[20]  E. Söderling,et al.  Long-term xylitol consumption and mutans streptococci in plaque and saliva. , 1991, Caries research.

[21]  D. Kandelman,et al.  A 24-month Clinical Study of the Incidence and Progression of Dental Caries in Relation to Consumption of Chewing Gum Containing Xylitol in School Preventive Programs , 1990, Journal of dental research.

[22]  R. Kent,et al.  Association of the Microbial Flora of Dental Plaque and Saliva with Human Root-surface Caries , 1990, Journal of dental research.

[23]  J. Tenovuo,et al.  Caries development in children in relation to the presence of mutans streptococci in dental plaque and of serum antibodies against whole cells and protein antigen I/II of Streptococcus mutans. , 1990, Caries research.

[24]  P. Alanen,et al.  Long-term effect of xylitol chewing gum on dental caries. , 1989, Community dentistry and oral epidemiology.

[25]  P. Alanen,et al.  Xylitol chewing gum in caries prevention: a field study in children. , 1988, Journal of the American Dental Association.

[26]  A. Scheinin,et al.  Effect of xylitol and sorbitol on polysaccharide production by and adhesive properties of Streptococcus mutans. , 1987, Caries research.

[27]  W. Loesche Role of Streptococcus mutans in human dental decay. , 1986, Microbiological reviews.

[28]  B. Jonsson,et al.  The effect of caries-preventive measures in mothers on dental caries and the oral presence of the bacteria Streptococcus mutans and lactobacilli in their children. , 1984, Archives of oral biology.

[29]  S. Alaluusua,et al.  Streptococcus mutans establishment and dental caries experience in children from 2 to 4 years old. , 1983, Scandinavian journal of dental research.

[30]  P. Green,et al.  Maternal salivary levels of Streptococcus mutans and primary oral infection of infants. , 1981, Archives of oral biology.

[31]  A. Scheinin,et al.  Turku sugar studies XX. Microbiological findings and plaque index values in relation to 1-year use of xylitol chewing gum. , 1976, Acta odontologica Scandinavica.

[32]  J C GREENE,et al.  THE SIMPLIFIED ORAL HYGIENE INDEX. , 1964, Journal of the American Dental Association.