Predicting the future of breast cancer

Two new studies suggest that tests based on Cyclin E or microarray analysis have the potential to outperform conventional criteria predicting the outcome of breast cancer.

[1]  Jane Stewart,et al.  Reinstatement of heroin self-administration habits: morphine prompts and naltrexone discourages renewed responding after extinction , 2005, Psychopharmacology.

[2]  S. Hyman,et al.  Addiction, Dopamine, and the Molecular Mechanisms of Memory , 2000, Neuron.

[3]  E T BELL,et al.  The Diseases of the Breast , 1925, Nature.

[4]  René Bernards,et al.  A progression puzzle. , 2002, Nature.

[5]  Van,et al.  A gene-expression signature as a predictor of survival in breast cancer. , 2002, The New England journal of medicine.

[6]  S. Reed,et al.  Deregulated cyclin E induces chromosome instability , 1999, Nature.

[7]  D. Surmeier,et al.  Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine , 1999, Nature.

[8]  C. D. HAAGENSEN,et al.  Diseases of the Breast , 1972 .

[9]  Carsten O. Peterson,et al.  Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. , 2001, Cancer research.

[10]  Mollianne J. McGahren,et al.  Tumor-Specific Proteolytic Processing of Cyclin E Generates Hyperactive Lower-Molecular-Weight Forms , 2001, Molecular and Cellular Biology.

[11]  David W. Self,et al.  Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour , 2003, Nature.

[12]  W. Schultz Getting Formal with Dopamine and Reward , 2002, Neuron.

[13]  Yudong D. He,et al.  Gene expression profiling predicts clinical outcome of breast cancer , 2002, Nature.

[14]  J. Sjöström Predictive Factors for Response to Chemotherapy in Advanced Breast Cancer , 2002, Acta oncologica.

[15]  Marc Payton,et al.  Cyclin E2, the cycle continues. , 2002, The international journal of biochemistry & cell biology.

[16]  E. Nestler,et al.  Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research. , 2000, Critical reviews in neurobiology.

[17]  Isabelle Bedrosian,et al.  Cyclin E and survival in patients with breast cancer. , 2002, The New England journal of medicine.

[18]  E. Nestler,et al.  Molecular neurobiology of addiction. , 2001, The American journal on addictions.

[19]  G. Landberg,et al.  The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node , 2002, Oncogene.

[20]  S. Reed,et al.  Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line , 2001, Nature.

[21]  Yudong D. He,et al.  A Gene-Expression Signature as a Predictor of Survival in Breast Cancer , 2002 .

[22]  R. Wise,et al.  Rewarding Actions of Phencyclidine and Related Drugs in Nucleus Accumbens Shell and Frontal Cortex , 1996, The Journal of Neuroscience.

[23]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[24]  Bruce T. Hope,et al.  Neuroadaptation: Incubation of cocaine craving after withdrawal , 2001, Nature.

[25]  Rodrigo Bermejo,et al.  Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization. , 2002, Molecular biology of the cell.

[26]  A. Amsel,et al.  Motivational properties of frustration. I. Effect on a running response of the addition of frustration to the motivational complex. , 1952, Journal of experimental psychology.

[27]  E. Nestler,et al.  Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens , 2001, The Journal of Neuroscience.