Automatic Initial Boundary Generation Methods Based on Edge Detectors for the Level Set Function of the Chan-Vese Segmentation Model and Applications in Biomedical Image Processing

Image segmentation is an important problem in image processing that has a wide range of applications in medicine, biomedicine and other fields of science and engineering. During the non-learning-based approaches, the techniques based on the partial differential equations and calculus of variation have attracted a lot of attention and acquired many achievements. Among the variational models, the Chan-Vese variational segmentation is a well-known model to solve the image segmentation problem. The level set methods are highly accurate methods to solve this model, and they do not depend on the edges. However, the performance of these methods depends on the level set function and its initial boundary too much. In this paper, we propose automatic initial boundary generation methods based on the edge detectors: Sobel, Prewitt, Roberts and Canny. In the experiments, we prove that among the four proposed initial boundary generation methods, the method based on the Canny edge detector brings the highest performance for the segmentation method. By combining the proposed initial boundary generation method based on the Canny edge detector, we implement the Chan-Vese model to segment biomedical images. Experimental results indicate we obtain improved segmentation results and compare different edge detectors in terms of performance.

[1]  Pascal Getreuer,et al.  Chan-Vese Segmentation , 2012, Image Process. Line.

[2]  D. Mumford,et al.  Optimal approximations by piecewise smooth functions and associated variational problems , 1989 .

[3]  Julia A. Schnabel,et al.  A level-set approach to joint image segmentation and registration with application to CT lung imaging , 2017, Comput. Medical Imaging Graph..

[4]  Guosheng Lin,et al.  Exploring Context with Deep Structured Models for Semantic Segmentation , 2016, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[5]  John F. Canny,et al.  A Computational Approach to Edge Detection , 1986, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[6]  V. B. Surya Prasath,et al.  Regularization Parameter Selection in Image Restoration with Inverse Gradient: Single Scale or Multiscale? , 2018, 2018 IEEE Seventh International Conference on Communications and Electronics (ICCE).

[7]  J. Morel,et al.  Variational Methods in Image Segmentation: with seven image processing experiments , 1994 .

[8]  Tony F. Chan,et al.  Active contours without edges , 2001, IEEE Trans. Image Process..

[9]  Bruce J. Aronow,et al.  Cell nuclei segmentation in glioma histopathology images with color decomposition based active contours , 2015, 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

[10]  S. D. Dvoenko,et al.  Image noise removal based on total variation , 2015 .

[11]  Hugo Proença,et al.  Fast and globally convex multiphase active contours for brain MRI segmentation , 2014, Comput. Vis. Image Underst..

[12]  Jean-Michel Morel,et al.  Variational methods in image segmentation , 1995 .

[13]  S. D. Dvoenko,et al.  A method of total variation to remove the mixed Poisson-Gaussian noise , 2016, Pattern Recognition and Image Analysis.