Amplitude-oriented exercise in Parkinson’s disease: a randomized study comparing LSVT-BIG and a short training protocol

LSVT-BIG is an exercise for patients with Parkinson’s disease (PD) comprising of 16 1-h sessions within 4 weeks. LSVT-BIG was compared with a 2-week short protocol (AOT-SP) consisting of 10 sessions with identical exercises in 42 patients with PD. UPDRS-III-score was reduced by −6.6 in LSVT-BIG and −5.7 in AOT-SP at follow-up after 16 weeks (p < 0.001). Measures of motor performance were equally improved by LSVT-BIG and AOT-SP but high-intensity LSVT-BIG was more effective to obtain patient-perceived benefit.

[1]  Andreas Kupsch,et al.  Comparing exercise in Parkinson's disease—the Berlin BIG Study , 2010, Movement disorders : official journal of the Movement Disorder Society.

[2]  A. Lees,et al.  What features improve the accuracy of clinical diagnosis in Parkinson's disease , 1992, Neurology.

[3]  M. Hallett,et al.  Neural correlates of dual task performance in patients with Parkinson’s disease , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.

[4]  Ralf Kauert,et al.  Reliabilitätsstudie zum Ganganalysesystem RehaWatch / Reliability of the novel gait analysis system RehaWatch , 2010, Biomedizinische Technik. Biomedical engineering.

[5]  Lynn Rochester,et al.  Evidence for motor learning in Parkinson's disease: Acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues , 2010, Brain Research.

[6]  P T Fox,et al.  Hypophonia in Parkinson’s disease , 2003, Neurology.

[7]  R. Fitzpatrick,et al.  The Parkinson's Disease Questionnaire (PDQ-39): development and validation of a Parkinson's disease summary index score. , 1997, Age and ageing.

[8]  V. Mathiowetz,et al.  Adult norms for the Box and Block Test of manual dexterity. , 1985, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[9]  Lorraine O. Ramig,et al.  Intensive Amplitude‐specific Therapeutic Approaches for Parkinson's Disease: Toward a Neuroplasticity‐principled Rehabilitation Model , 2008 .

[10]  Linda Tickle-Degnen,et al.  Self‐management rehabilitation and health‐related quality of life in Parkinson's disease: A randomized controlled trial , 2010, Movement disorders : official journal of the Movement Disorder Society.

[11]  J. Summers,et al.  Stride length regulation in Parkinson's disease. Normalization strategies and underlying mechanisms. , 1996, Brain : a journal of neurology.

[12]  Catherine Sackley,et al.  Physiotherapy intervention in Parkinson’s disease: systematic review and meta-analysis , 2012, BMJ : British Medical Journal.