论文信息 - Long-Term Diazoxide Treatment in Persistent Hyperinsulincmic Hypoglycemia of Infancy: A Case Report

Long-Term Diazoxide Treatment in Persistent Hyperinsulincmic Hypoglycemia of Infancy: A Case Report

Long-term diazoxide and somatostatin analogue have been used in the treatment of persistent hyperinsulinemic hypoglycemia of infancy albeit with some side effects. We report a case with persistent hyperinsulinemic hypoglycemia who has been on diazoxide therapy for 4.5 years. Diazoxide treatment maintained normoglycemia without causing any side effects, including hypertrichosis.

F. Baş | R. Bundak | N. Saka | H. Günöz | Ali M. Darendeliler

[1] B. Glaser,et al. Persistent hyperinsulinemic hypoglycemia of infancy: long-term octreotide treatment without pancreatectomy. , 1993, The Journal of pediatrics.

[2] C. Alter,et al. Short- and long-term use of octreotide in the treatment of congenital hyperinsulinism. , 1993, The Journal of pediatrics.

[3] T. Declue,et al. Linear growth during long-term treatment with somatostatin analog (SMS 201-995) for persistent hyperinsulinemic hypoglycemia of infancy. , 1990, The Journal of pediatrics.

[4] M. Haymond. Hypoglycemia in infants and children. , 1989, Endocrinology and metabolism clinics of North America.

[5] P. Hindmarsh,et al. Somatostatin analogue in short term management of hyperinsulinism. , 1988, Archives of disease in childhood.

[6] D. Dunger,et al. Long-term treatment with diazoxide in childhood hyperinsulinism. , 1986, Acta endocrinologica. Supplementum.

[7] D. Price,et al. Complications of diazoxide in the treatment of nesidioblastosis. , 1985, Archives of disease in childhood.