The Alcohol-Aggression Relationship and Differential Sensitivity to Alcohol

The determination of which individuals are at risk of responding aggressively when intoxicated and under what conditions this is likely to occur is basic to understanding the alcohol/aggression relationship. Three theorized mechanisms on which individuals display differential vulnerability and which are related to risk are discussed. These are the cue for reinforcement system, the threat system, and the executive control system. Under the latter heading new findings from a number of studies are presented which demonstrate that: under low provocation intoxicated executive cognitive functioning (ECF) individuals performed with significantly more aggression than sober or intoxicated high ECF individuals; that individuals with low ECF, though more aggressive, choose these responses more slowly than those with high ECF; that low ECF, unlike high ECF, individuals do not react to anticipated shock; and, it is specifically low sober state ECF individuals who show increased alcohol induced ECF disruption who are most at risk for intoxicated aggression.

[1]  Ting-kai Li,et al.  Microdialysis of dopamine in the nucleus accumbens of alcohol-preferring (P) rats during anticipation and operant self-administration of ethanol. , 2002, Alcoholism, clinical and experimental research.

[2]  R. Bevins Novelty Seeking and Reward: Implications for the Study of High-Risk Behaviors , 2001 .

[3]  N. Birbaumer,et al.  Alcohol Affects Emotion Through Cognition , 2001, Psychological science.

[4]  P. Conrod,et al.  Reliability and validity of alcohol-induced heart rate increase as a measure of sensitivity to the stimulant properties of alcohol , 2001, Psychopharmacology.

[5]  A. Dagher,et al.  Acute ethanol consumption increases synaptic dopamine in ventral striatum: a PET / 11C-raclopride study in healthy volunteers , 2001, NeuroImage.

[6]  M. Vogel-Sprott,et al.  Maintaining intentional control of behavior under alcohol. , 2001, Alcoholism, clinical and experimental research.

[7]  C. Ávila,et al.  Distinguishing BIS-mediated and BAS-mediated disinhibition mechanisms: a comparison of disinhibition models of Gray (1981, 1987) and of Patterson and Newman (1993). , 2001, Journal of personality and social psychology.

[8]  P. Giancola Executive functioning: a conceptual framework for alcohol-related aggression. , 2000, Experimental and clinical psychopharmacology.

[9]  Con Stough,et al.  Alcohol impairs speed of information processing and simple and choice reaction time and differentially impairs higher-order cognitive abilities , 2000 .

[10]  S. Ekholm,et al.  Reduced regional cerebral blood flow in non-psychotic violent offenders , 2000, Psychiatry Research: Neuroimaging.

[11]  A. Raine,et al.  Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. , 2000, Archives of general psychiatry.

[12]  B. Tiplady,et al.  Effects of ethanol and temazepam on episodic and semantic memory: a dose–response comparison , 1999 .

[13]  R. Pihl,et al.  Motivational effects of alcohol on memory consolidation and heart rate in social drinkers. , 1999, Alcoholism, clinical and experimental research.

[14]  S. Chermack,et al.  Construct validity of laboratory aggression paradigms: A response to tedeschi and quigley (1996) , 1998 .

[15]  R. Pihl,et al.  Cognitive functioning and the inhibition of alcohol-induced aggression. , 1998, Journal of studies on alcohol.

[16]  Tim Shallice,et al.  The domain of supervisory processes and the temporal organisation of behaviour , 1998 .

[17]  C. Anderson,et al.  External Validity of “Trivial” Experiments: The Case of Laboratory Aggression , 1997 .

[18]  P. Conrod,et al.  Biphasic effects of alcohol on heart rate are influenced by alcoholic family history and rate of alcohol ingestion. , 1997, Alcoholism, clinical and experimental research.

[19]  T. Robbins Dissociating executive functions of the prefrontal cortex. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[20]  T Shallice,et al.  The domain of supervisory processes and temporal organization of behaviour. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[21]  R. Thisted,et al.  Brain SPECT findings and aggressiveness. , 1996, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists.

[22]  Plum,et al.  Impulsive Homicide Associated With an Arachnoid Cyst and Unilateral Frontotemporal Cerebral Dysfunction. , 1996, Seminars in Clinical Neuropsychiatry.

[23]  R. Pihl,et al.  Assessment of measures of impulsivity in healthy male volunteers , 1995 .

[24]  R. Pihl,et al.  Cognitive and neuropsychological characteristics of physically aggressive boys. , 1995, Journal of abnormal psychology.

[25]  R. Pihl,et al.  Alcoholism: the role of different motivational systems. , 1995, Journal of psychiatry & neuroscience : JPN.

[26]  J. Halperin,et al.  Impulsivity and the initiation of fights in children with disruptive behavior disorders. , 1995, Journal of child psychology and psychiatry, and allied disciplines.

[27]  P. Conrod,et al.  Autonomic reactivity and alcohol-induced dampening in men at risk for alcoholism and men at risk for hypertension. , 1995, Alcoholism, clinical and experimental research.

[28]  A. Bond,et al.  The effect of tryptophan depletion and enhancement on subjective and behavioural aggression in normal male subjects , 1995, Psychopharmacology.

[29]  R. Pihl,et al.  Provocation, acute alcohol intoxication, cognitive performance, and aggression. , 1995, Journal of abnormal psychology.

[30]  Sheilagh Hodgins,et al.  Ventral frontal deficits in psychopathy: Neuropsychological test findings , 1995, Neuropsychologia.

[31]  A. Zeichner,et al.  Neuropsychological performance on tests of frontal-lobe functioning and aggressive behavior in men. , 1994, Journal of abnormal psychology.

[32]  P. Dobkin,et al.  Predicting early onset of male antisocial behavior from preschool behavior. , 1994, Archives of general psychiatry.

[33]  J. Crabbe,et al.  Genetic animal models of alcohol and drug abuse. , 1994, Science.

[34]  T. Arbuckle,et al.  Social drinking and cognitive functioning revisited: the role of intellectual endowment and psychological distress. , 1994, Journal of studies on alcohol.

[35]  D. Mungas,et al.  Effects of acute alcohol administration on verbal and spatial learning. , 1994, Alcohol and alcoholism.

[36]  R. Pihl,et al.  Cardiovascular reactivity as a predictor of alcohol consumption in a taste test situation. , 1994, Journal of clinical psychology.

[37]  Adrian Raine,et al.  The Psychopathology of Crime: Criminal Behavior as a Clinical Disorder , 1993 .

[38]  R. Pihl,et al.  A biosocial model of the alcohol-aggression relationship. , 1993, Journal of studies on alcohol. Supplement.

[39]  M. Sayette,et al.  Alcohol and aggression: a social information processing analysis. , 1993, Journal of studies on alcohol.

[40]  R. Pihl,et al.  Heart-rate reactivity and alcohol consumption among sons of male alcoholics and sons of non-alcoholics. , 1993, Journal of psychiatry & neuroscience : JPN.

[41]  Alan C. Evans,et al.  Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Stevens S. Smith,et al.  Neuropsychological differentiation of psychopathic and nonpsychopathic criminal offenders. , 1992 .

[43]  R. Pihl,et al.  The effects of alcohol on the cardiovascular stress response in men at high risk for alcoholism: a dose response study. , 1992, Journal of studies on alcohol.

[44]  P. Goldman-Rakic Working memory and the mind. , 1992, Scientific American.

[45]  K. Sher,et al.  Using adapted short MASTs for assessing parental alcoholism: reliability and validity. , 1992, Alcoholism, clinical and experimental research.

[46]  R. Pihl,et al.  Alcohol and crimes of violence: present issues. , 1990, The International journal of the addictions.

[47]  R. Pihl,et al.  Inherited predisposition to alcoholism: characteristics of sons of male alcoholics. , 1990, Journal of abnormal psychology.

[48]  P. Zelazo,et al.  Acute alcohol intoxication and cognitive functioning. , 1990, Journal of studies on alcohol.

[49]  R. Pihl,et al.  Effects of alcohol on psychophysiological hyperreactivity to nonaversive and aversive stimuli in men at high risk for alcoholism. , 1990, Journal of abnormal psychology.

[50]  P. Piazza,et al.  Experimental approach to individual vulnerability to psychostimulant addiction , 1989, Neuroscience & Biobehavioral Reviews.

[51]  R. Heinrichs Frontal cerebral lesions and violent incidents in chronic neuropsychiatrie patients , 1989, Biological Psychiatry.

[52]  R. Wise Psychomotor Stimulant Properties of Addictive Drugs , 1988, Annals of the New York Academy of Sciences.

[53]  J. Gray,et al.  Perspectives on Anxiety and Impulsivity: A Commentary , 1987 .

[54]  J. Laberg,et al.  Psychophysiological indicators of craving in alcoholics: effects of cue exposure. , 1987, British journal of addiction.

[55]  R. Wise,et al.  A psychomotor stimulant theory of addiction. , 1987, Psychological review.

[56]  E. Gorenstein Cognitive-perceptual deficit in an alcoholism spectrum disorder. , 1987, Journal of studies on alcohol.

[57]  C. Robert Cloninger,et al.  Neurogenetic adaptive mechanisms in alcoholism. , 1987, Science.

[58]  M. Petrides Deficits on conditional associative-learning tasks after frontal- and temporal-lobe lesions in man , 1985, Neuropsychologia.

[59]  J. Newman,et al.  Passive avoidance in syndromes of disinhibition: psychopathy and extraversion. , 1985, Journal of personality and social psychology.

[60]  B. Milner,et al.  Deficits on subject-ordered tasks after frontal- and temporal-lobe lesions in man , 1982, Neuropsychologia.

[61]  R. Niaura,et al.  Attentional processes in alcohol-mediated aggression. , 1982, Journal of studies on alcohol.

[62]  T. Shallice Specific impairments of planning. , 1982, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[63]  J. Hull A self-awareness model of the causes and effects of alcohol consumption. , 1981, Journal of abnormal psychology.

[64]  R. Pihl,et al.  Effects of alcohol and instigator intent on human aggression. , 1980, Journal of studies on alcohol.

[65]  R. Pihl,et al.  Effects of alcohol and behavior contingencies on human aggression. , 1979, Journal of abnormal psychology.

[66]  Spencer A. Rathus,et al.  A 30-item schedule for assessing assertive behavior , 1973 .

[67]  R. Pihl,et al.  Executive cognitive functioning and aggression: Is it an issue of impulsivity? , 2003 .

[68]  D. Fowles Biological variables in psychopathology: A psychobiological perspective. , 2002 .

[69]  R. Krueger,et al.  Sources of covariation among attention-deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder: the importance of shared environment. , 2001, Journal of abnormal psychology.

[70]  J. Roizen,et al.  Epidemiological issues in alcohol-related violence. , 1997, Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism.

[71]  R. Pihl,et al.  Cognitive performance, monetary incentive, and aggression , 1996 .

[72]  J. Thome,et al.  Sensation seeking, alcoholism and dopamine activity , 1996, European Psychiatry.

[73]  P. Giancola EVidence for dorsolateral and orbital prefrontal cortical involvement in the expression of aggressive behavior , 1995 .

[74]  A. Damasio Descartes' error: emotion, reason, and the human brain. avon books , 1994 .

[75]  Terrie E. Moffitt,et al.  The neuropsychology of conduct disorder , 1993, Development and Psychopathology.

[76]  H. Quay The behavioral reward and inhibition system in childhood behavior disorder. , 1988 .

[77]  T. McAllister,et al.  Aspects of the behavior of psychiatric inpatients with frontal lobe damage: some implications for diagnosis and treatment. , 1987, Comprehensive psychiatry.

[78]  J. Gray,et al.  The neuropsychology of anxiety. , 1985, Issues in mental health nursing.

[79]  D. Fowles Biological Variables in Psychopathology , 1984 .