Current and Future Perspectives on Light Therapy Using Wearable Devices

Circadian rhythm is the internal clock that regulates physiological functions, including the sleep-wake cycle. Advancements in technology and lifestyle have negatively impacted the circadian rhythm, resulting in numerous sleep disorders. Because light is the most important “zeigeber” for synchronizing the circadian system, light therapy is effective for circadian rhythm sleep disorders. We compared light therapy glasses with a traditional light therapy box, summarized the characteristics of various light therapy glasses, and proposed future applications of wearable sleep technologies in light therapy.

[1]  A. Herxheimer,et al.  The prevention and treatment of jet lag , 2003, BMJ : British Medical Journal.

[2]  K. Hirata,et al.  Sleep disorders in the elderly: Diagnosis and management , 2017, Journal of general and family medicine.

[3]  Jon C. Cole,et al.  Chronic Jet Lag Produces Cognitive Deficits , 2000, The Journal of Neuroscience.

[4]  K. Sharkey,et al.  Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 20 , 2015, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[5]  D. Kripke,et al.  Human circadian phase–response curves for exercise , 2019, The Journal of physiology.

[6]  A. Viola,et al.  Light therapy with boxes or glasses to counteract effects of acute sleep deprivation , 2019, Scientific Reports.

[7]  M. Lorist,et al.  Human sleep and cognition. Part 2 , 2011 .

[8]  K. Ou,et al.  Differences in cortisol profiles and circadian adjustment time between nurses working night shifts and regular day shifts: A prospective longitudinal study. , 2015, International journal of nursing studies.

[9]  A. Knutsson,et al.  Health disorders of shift workers. , 2003, Occupational medicine.

[10]  P. Peigneux,et al.  Afternoon Nap and Bright Light Exposure Improve Cognitive Flexibility Post Lunch , 2015, PloS one.

[11]  D. Skene,et al.  The relevance of daylight for humans. , 2020, Biochemical pharmacology.

[12]  D Dawson,et al.  Improving adaptation to simulated night shift: timed exposure to bright light versus daytime melatonin administration. , 1995, Sleep.

[13]  R. Sack.  The pathophysiology of jet lag. , 2009, Travel medicine and infectious disease.

[14]  Mari Hysing,et al.  Sleep and use of electronic devices in adolescence: results from a large population-based study , 2015, BMJ Open.

[15]  S. Drummond,et al.  Wearable Technologies for Developing Sleep and Circadian Biomarkers: A Summary of Workshop Discussions. , 2019, Sleep.

[16]  S. Lockley,et al.  A Blue-Enriched, Increased Intensity Light Intervention to Improve Alertness and Performance in Rotating Night Shift Workers in an Operational Setting , 2021, Nature and science of sleep.

[17]  C. Eastman,et al.  Practical Interventions to Promote Circadian Adaptation to Permanent Night Shift Work: Study 4 , 2009, Journal of biological rhythms.

[18]  H. Wright,et al.  The effect of evening bright light in delaying the circadian rhythms and lengthening the sleep of early morning awakening insomniacs. , 1993, Sleep.

[19]  S. Lockley,et al.  Randomised controlled trial of the efficacy of a blue-enriched light intervention to improve alertness and performance in night shift workers , 2017, Occupational and Environmental Medicine.

[20]  M. Sarlo,et al.  Sensors Capabilities, Performance, and Use of Consumer Sleep Technology. , 2020, Sleep medicine clinics.

[21]  C. Drake,et al.  Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers. , 2004, Sleep.

[22]  D. Dijk,et al.  Light therapies to improve sleep in intrinsic circadian rhythm sleep disorders and neuro-psychiatric illness: A systematic review and meta-analysis. , 2019, Sleep medicine reviews.

[23]  P. Zee,et al.  Therapeutics for Circadian Rhythm Sleep Disorders. , 2010, Sleep medicine clinics.

[24]  D. Kripke,et al.  Efficacy of Enhanced Evening Light for Advanced Sleep Phase Syndrome , 2003, Behavioral sleep medicine.

[25]  R. Reiter,et al.  Melatonin feedback on clock genes: a theory involving the proteasome , 2015, Journal of pineal research.

[26]  T. Brown.  Melanopic illuminance defines the magnitude of human circadian light responses under a wide range of conditions , 2020, Journal of pineal research.

[27]  T. Legenbauer,et al.  Feasibility and Efficacy of Bright Light Therapy in Depressed Adolescent Inpatients. , 2018, Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie.

[28]  J. Wyatt.  Delayed sleep phase syndrome: pathophysiology and treatment options. , 2004, Sleep.

[29]  Shadab A. Rahman,et al.  Characterizing the temporal Dynamics of Melatonin and Cortisol Changes in Response to Nocturnal Light Exposure , 2019, Scientific Reports.

[30]  M. Figueiro.  Delayed sleep phase disorder: clinical perspective with a focus on light therapy , 2016, Nature and science of sleep.

[31]  H. Wright,et al.  The treatment of early-morning awakening insomnia with 2 evenings of bright light. , 2005, Sleep.

[32]  Hoon-Ki Sung,et al.  Feeding Rhythms and the Circadian Regulation of Metabolism , 2020, Frontiers in Nutrition.

[33]  A. Goldstone,et al.  Wearable Sleep Technology in Clinical and Research Settings. , 2019, Medicine and science in sports and exercise.

[34]  M. H. Do.  Melanopsin and the Intrinsically Photosensitive Retinal Ganglion Cells: Biophysics to Behavior , 2019, Neuron.

[35]  Philippe Boudreau,et al.  Impacts of shift work on sleep and circadian rhythms. , 2014, Pathologie-biologie.

[36]  J. Cipolla-Neto,et al.  Melatonin as a Hormone: New Physiological and Clinical Insights. , 2018, Endocrine reviews.

[37]  D. Golombek,et al.  Physiology of circadian entrainment. , 2010, Physiological reviews.

[38]  Gregory D M Potter,et al.  The Future of Shift Work: Circadian Biology Meets Personalised Medicine and Behavioural Science , 2020, Frontiers in Nutrition.

[39]  P. Angeli,et al.  Effect of Morning Light Glasses and Night Short-Wavelength Filter Glasses on Sleep-Wake Rhythmicity in Medical Inpatients , 2020, Frontiers in Physiology.

[40]  T. Shochat,et al.  Impact of lifestyle and technology developments on sleep , 2012, Nature and science of sleep.

[41]  M. Spitschan.  Melanopsin contributions to non-visual and visual function , 2019, Current Opinion in Behavioral Sciences.

[42]  Phyllis C Zee,et al.  Circadian Rhythm Abnormalities , 2013, Continuum.

[43]  G. Kecklund,et al.  Health consequences of shift work and insufficient sleep , 2016, British Medical Journal.

[44]  F. Oort,et al.  The effects of light therapy on sleep problems: A systematic review and meta-analysis. , 2016, Sleep medicine reviews.