From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics
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J. Swen | B. Wilffert | A. H. Maitland‐van der Zee | D. Touw | V. Deneer | H. Mulder | Knmp working group Pharmacogenetics
[1] S. Kaul,et al. ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA “Boxed Warning”: A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association , 2010, Circulation.
[2] B. Yan,et al. Role of warfarin pharmacogenetic testing in clinical practice. , 2010, Pharmacogenomics.
[3] Janet Woodcock,et al. Pharmacogenetics--tailoring treatment for the outliers. , 2009, The New England journal of medicine.
[4] Charles E. Leonard,et al. CYP2C9, CYP2C19, and ABCB1 Genotype and Hospitalization for Phenytoin Toxicity , 2009, Journal of clinical pharmacology.
[5] R. Dworkin,et al. Treatment of neuropathic pain: an overview of recent guidelines. , 2009, The American journal of medicine.
[6] I. Cascorbi,et al. Conference Scene: Pharmacogenomics at the second PharmSciFair 2009: adverse drug reactions and clinical implementation. , 2009, Pharmacogenomics.
[7] M. Daly,et al. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin , 2009, Nature Genetics.
[8] L. Becquemont,et al. Pharmacogenomics of adverse drug reactions: practical applications and perspectives. , 2009, Pharmacogenomics.
[9] E. Antman,et al. Cytochrome p-450 polymorphisms and response to clopidogrel. , 2009, The New England journal of medicine.
[10] E. Antman,et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial , 2009, The Lancet.
[11] R. Altman,et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. , 2009, The New England journal of medicine.
[12] Erika Check Hayden,et al. Genome sequencing: the third generation , 2009, Nature.
[13] B. Franke,et al. HTR2C Gene Polymorphisms and the Metabolic Syndrome in Patients With Schizophrenia: A Replication Study , 2009, Journal of clinical psychopharmacology.
[14] S‐M Huang,et al. Is This the Drug or Dose for You?: Impact and Consideration of Ethnic Factors in Global Drug Development, Regulatory Review, and Clinical Practice , 2008, Clinical pharmacology and therapeutics.
[15] M. Ingelman-Sundberg,et al. Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects , 2008, European Journal of Clinical Pharmacology.
[16] K. Hillgren,et al. PhRMA White Paper on ADME Pharmacogenomics , 2008, Journal of clinical pharmacology.
[17] P. Weihe,et al. CYP2D6 Polymorphism in Relation to Tramadol Metabolism: A Study of Faroese Patients , 2008, Therapeutic drug monitoring.
[18] H. Guchelaar,et al. Pharmacogenetics: From Bench to Byte , 2008, Clinical pharmacology and therapeutics.
[19] G. Jenkins,et al. Pharmacokinetic Genes Do Not Influence Response or Tolerance to Citalopram in the STAR*D Sample , 2008, PloS one.
[20] K. P. Mathews,et al. Acenocoumarol and phenytoin toxicity in the presence of CYP2C9 mutation. , 2008, The Journal of the Association of Physicians of India.
[21] S. Mallal,et al. HLA-B*5701 screening for hypersensitivity to abacavir. , 2008, The New England journal of medicine.
[22] H. Refsum,et al. Impact of the Ultrarapid CYP2C19*17 Allele on Serum Concentration of Escitalopram in Psychiatric Patients , 2008, Clinical pharmacology and therapeutics.
[23] Jung-Eun Choi,et al. Lack of association between the −759C/T polymorphism of the 5‐HT2C receptor gene and olanzapine‐induced weight gain among Korean schizophrenic patients , 2008, Journal of clinical pharmacy and therapeutics.
[24] J. Brockmöller,et al. Effects of the CYP2D6 Gene Duplication on the Pharmacokinetics and Pharmacodynamics of Tramadol , 2008, Journal of clinical psychopharmacology.
[25] E. Antman,et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. , 2007, The New England journal of medicine.
[26] S. Narayan,et al. Severe phenytoin toxicity in a CYP2C9*3*3 homozygous mutant from India. , 2007, Neurology India.
[27] J. Kennedy,et al. Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis. , 2007, The international journal of neuropsychopharmacology.
[28] B. Franke,et al. The association between HTR2C polymorphisms and obesity in psychiatric patients using antipsychotics: a cross-sectional study , 2007, The Pharmacogenomics Journal.
[29] Henk-Jan Guchelaar,et al. Translating Pharmacogenomics: Challenges on the Road to the Clinic , 2007, PLoS medicine.
[30] B. Franke,et al. The Association Between HTR2C Gene Polymorphisms and the Metabolic Syndrome in Patients With Schizophrenia , 2007, Journal of clinical psychopharmacology.
[31] Soo-Youn Lee,et al. Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting. , 2007, Journal of biochemistry and molecular biology.
[32] Y. Wing,et al. Phenotype-genotype Relationship and Clinical Effects of Citalopram in Chinese Patients , 2006, Journal of clinical psychopharmacology.
[33] G. Reynolds,et al. The 5-HT2C receptor and antipsychoticinduced weight gain – mechanisms and genetics , 2006, Journal of psychopharmacology.
[34] C. Adithan,et al. Influence of the CYP2C9 AND CYP2C19 polymorphisms on phenytoin hydroxylation in healthy individuals from south India. , 2006, The Indian journal of medical research.
[35] H. Refsum,et al. Heterozygous Mutation in CYP2C19 Significantly Increases the Concentration/Dose Ratio of Racemic Citalopram and Escitalopram (S-citalopram) , 2006, Therapeutic drug monitoring.
[36] L. Arendt-Nielsen,et al. The Analgesic Effect of Tramadol After Intravenous Injection in Healthy Volunteers in Relation to CYP2D6 , 2006, Anesthesia and analgesia.
[37] G. Reynolds,et al. The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment , 2005, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[38] Deborah A Nickerson,et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. , 2005, The New England journal of medicine.
[39] Josemir W Sander,et al. Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[40] G. Reynolds,et al. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis , 2005, Pharmacogenetics and genomics.
[41] M. Margaglione,et al. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. , 2005 .
[42] Chih-Chuan Chen,et al. Dosage Recommendation of Phenytoin for Patients with Epilepsy with Different CYP2C9/CYP2C19 Polymorphisms , 2004, Therapeutic drug monitoring.
[43] Urs A. Meyer,et al. Pharmacogenetics – five decades of therapeutic lessons from genetic diversity , 2004, Nature Reviews Genetics.
[44] J. Hebebrand,et al. Lack of association between the –759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals , 2004, Psychiatric genetics.
[45] Yuan-Tsong Chen,et al. A marker for Stevens–Johnson syndrome , 2004 .
[46] Andreas Fregin,et al. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2 , 2004, Nature.
[47] A. Khvorova,et al. Identification of the gene for vitamin K epoxide reductase , 2004, Nature.
[48] S. Takashiba,et al. CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects. , 2004, Life sciences.
[49] T. Thum,et al. A rapid and simple CYP2D6 genotyping assay--case study with the analgetic tramadol. , 2003, Metabolism: clinical and experimental.
[50] Zhaoqian Liu,et al. Pharmacokinetics of citalopram in relation to genetic polymorphism of CYP2C19. , 2003, Drug metabolism and disposition: the biological fate of chemicals.
[51] L. Bertilsson,et al. Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes. , 2003, British journal of clinical pharmacology.
[52] A. Hoeft,et al. Impact of CYP2D6 genotype on postoperative tramadol analgesia , 2003, Pain.
[53] G. Reynolds,et al. Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain. , 2003, The American journal of psychiatry.
[54] R. Weinshilboum. Inheritance and drug response. , 2003, The New England journal of medicine.
[55] R. Ismail,et al. Correlation of tramadol pharmacokinetics and CYP2D6*10 genotype in Malaysian subjects. , 2002, Journal of pharmaceutical and biomedical analysis.
[56] G. Kearns,et al. Concordance between Tramadol and Dextromethorphan Parent/Metabolite Ratios: The Influence of CYP2D6 and Non‐CYP2D6 Pathways on Biotransformation , 2002, Journal of clinical pharmacology.
[57] A. Wood,et al. Phenytoin metabolic ratio: a putative marker of CYP2C9 activity in vivo. , 2001, Pharmacogenetics.
[58] E. Spina,et al. Severe phenytoin intoxication in a subject homozygous for CYP2C9*3 , 2001, Clinical pharmacology and therapeutics.
[59] J. Weide,et al. The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. , 2001, Pharmacogenetics.
[60] N. Peet,et al. Pharmacogenomics: challenges and opportunities. , 2001, Drug discovery today.
[61] D. Collier,et al. Pharmacogenetic prediction of clozapine response , 2000, The Lancet.
[62] S. Higuchi,et al. Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication. , 2000, Therapeutic drug monitoring.
[63] J. Brockmöller,et al. Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin. , 1999, British journal of clinical pharmacology.
[64] M C Meyer,et al. Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele. , 1999, Pharmacogenetics.
[65] J. Lieberman,et al. Serotonergic basis of antipsychotic drug effects in schizophrenia , 1998, Biological Psychiatry.
[66] E. Yukawa,et al. The Effects of Genetic Polymorphisms of CYP2C9 and CYP2C 19 on Phenytoin Metabolism in Japanese Adult Patients with Epilepsy: Studies in Stereoselective Hydroxylation and Population Pharmacokinetics , 1998, Epilepsia.
[67] R. Frye,et al. Debilitating Reaction following the Initial Dose of Tramadol , 1997, The Annals of pharmacotherapy.
[68] K. Furusho,et al. Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy , 1997, Clinical pharmacology and therapeutics.
[69] L. Arendt-Nielsen,et al. The hypoalgesic effect of tramadol in relation to CYP2D6 * , 1996, Clinical pharmacology and therapeutics.
[70] B. Wilffert,et al. Influence of tramadol on neurotransmitter systems of the rat brain. , 1996, Arzneimittel-Forschung.
[71] M. Takano,et al. Effect of CYP2C polymorphisms on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. , 1996, Biological & pharmaceutical bulletin.
[72] P. Baumann,et al. A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: a clinical, pharmacokinetic, and pharmacogenetic investigation. , 1996, Journal of clinical psychopharmacology.
[73] K. Brøsen,et al. Pharmacokinetics of Citalopram in Relation to the Sparteine and the Mephenytoin Oxidation Polymorphisms , 1993, Therapeutic drug monitoring.
[74] M. Bullock,et al. Phenytoin Toxicity Due to Genetic Polymorphism , 2009, Neurocritical care.
[75] M. Niermeijer. [Partial resistance to acenocoumarol and phenprocoumon caused by enzyme polymorphism]. , 2006, Nederlandsch tijdschrift voor geneeskunde.
[76] U. Brinkmann,et al. The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels , 2001, The Pharmacogenomics Journal.
[77] H. Dengler,et al. PHARMACOKINETICS AND DISPOSITION , 1997 .