Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer.
暂无分享,去创建一个
Didier Merlin | P. Garg | D. Merlin | A. Gewirtz | D. Sarma | S. Sitaraman | Andrew T Gewirtz | Shanthi V Sitaraman | Pallavi Garg | Dittakavi Sarma | Sabrina Jeppsson | Neal R Patel | Sabrina Jeppsson | Neal R. Patel
[1] M. Rojas,et al. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. , 2005, Gastroenterology.
[2] M. Banerjee,et al. Correlation of bcl-2 oncoprotein immunohistochemical expression with proliferation index and histopathologic parameters in colorectal neoplasia , 1999, Pathology & Oncology Research.
[3] J. Hickman,et al. Apoptosis induced by anticancer drugs , 1992, Cancer and Metastasis Reviews.
[4] C. Wolf‐Peeters,et al. Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin. , 1997, The American journal of pathology.
[5] R. Coffey,et al. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. , 1994, Gastroenterology.
[6] Takuji Tanaka,et al. A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate , 2003, Cancer science.
[7] J. Roman,et al. Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. , 2007, Gastroenterology.
[8] K. Kinzler,et al. Erratum: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene , 1992, Science.
[9] Hans Clevers,et al. Signaling pathways in intestinal development and cancer. , 2004, Annual review of cell and developmental biology.
[10] A Cumano,et al. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. , 2000, Molecular cell.
[11] P. Choi,et al. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention. , 1994, Gut.
[12] S. Srinivasan,et al. Blockade of adenosine A2B receptors ameliorates murine colitis , 2008, British journal of pharmacology.
[13] Hans Clevers,et al. Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC , 1997, Science.
[14] S. Spechler,et al. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer , 2009, Nature Reviews Gastroenterology &Hepatology.
[15] E. Suh,et al. The role of Cdx proteins in intestinal development and cancer , 2004, Cancer biology & therapy.
[16] D. Hanahan,et al. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. , 1999, Genes & development.
[17] R. Okamoto,et al. Cellular and Molecular Mechanisms of the Epithelial Repair in IBD , 2005, Digestive diseases and sciences.
[18] L. Matrisian,et al. Matrilysin (matrix metalloproteinase‐7) expression in ulcerative colitis–related tumorigenesis † , 2002, Molecular carcinogenesis.
[19] S. Gruber,et al. Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[20] Z. Werb,et al. New functions for the matrix metalloproteinases in cancer progression , 2002, Nature Reviews Cancer.
[21] A. Pozzi,et al. Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis , 2002, Oncogene.
[22] M. Abreu,et al. Role of Toll-like receptors in gastrointestinal malignancies , 2008, Oncogene.
[23] D. Hanahan,et al. MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis , 2000, Cell.
[24] C. Henkel,et al. MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells. , 2007, International journal of oncology.
[25] Vikram Devgan,et al. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. , 2005, Genes & development.
[26] C. J. Taylor,et al. Matrix metalloproteinase levels are elevated in inflammatory bowel disease. , 1999, Gastroenterology.
[27] I. Nishimoto,et al. Expression of gelatinases A and B, stromelysin-3 and matrilysin genes in breast carcinomas: clinico-pathological correlations , 1998, Clinical & Experimental Metastasis.
[28] E. Loftus. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. , 2004, Gastroenterology.
[29] Q. S. Wang,et al. Transcription factor NF-kappaB participates in regulation of epithelial cell turnover in the colon. , 2000, American journal of physiology. Gastrointestinal and liver physiology.
[30] P. Munkholm,et al. Colorectal cancer risk and mortality in patients with ulcerative colitis. , 1992, Gastroenterology.
[31] Hans Clevers,et al. Caught up in a Wnt storm: Wnt signaling in cancer. , 2003, Biochimica et biophysica acta.
[32] Hans Clevers,et al. Notch1 functions as a tumor suppressor in mouse skin , 2003, Nature Genetics.
[33] T. Brabletz,et al. Gastrointestinal stem cells in development and cancer , 2009, The Journal of pathology.
[34] C. V. van Noorden,et al. The role of gelatinases in colorectal cancer progression and metastasis. , 2004, Biochimica et biophysica acta.
[35] C. Fiocchi. Inflammatory bowel disease: etiology and pathogenesis. , 1998, Gastroenterology.
[36] S. Waldman,et al. Tumor Epithelial Cell Matrix Metalloproteinase 9 Is a Target for Antimetastatic Therapy in Colorectal Cancer , 2006, Clinical Cancer Research.
[37] K. Higuchi,et al. Increased proliferation of middle to distal colonic cells during colorectal carcinogenesis in experimental murine ulcerative colitis. , 2007, Oncology reports.
[38] Marina Pasca di Magliano,et al. Hedgehog signalling in cancer formation and maintenance , 2003, Nature Reviews Cancer.
[39] C. Harris,et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. , 1998, Cancer research.
[40] G. Bouma,et al. The immunological and genetic basis of inflammatory bowel disease , 2003, Nature Reviews Immunology.
[41] M. Björklund,et al. Gelatinase-mediated migration and invasion of cancer cells. , 2005, Biochimica et biophysica acta.
[42] P. Garg,et al. Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis. , 2009, American journal of physiology. Gastrointestinal and liver physiology.
[43] Riccardo Fodde,et al. Wnt/β-catenin signaling in cancer stemness and malignant behavior , 2007 .
[44] K. Raj,et al. The role of Notch in tumorigenesis: oncogene or tumour suppressor? , 2003, Nature Reviews Cancer.
[45] P. Prior,et al. Mortality in Crohn's disease. , 1981, Lancet.
[46] T. Ohkusa,et al. Promotion of colorectal neoplasia in experimental murine ulcerative colitis. , 1996, Gut.
[47] Tetsuya Nakamura,et al. Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision , 2007, Journal of Gastroenterology.
[48] F. Radtke,et al. Notch and cancer: a double-edged sword , 2007, Cellular and Molecular Life Sciences.
[49] K. Abrams,et al. The risk of colorectal cancer in ulcerative colitis: a meta-analysis , 2001, Gut.
[50] M. Sinnamon,et al. Matrix metalloproteinase‐9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse , 2008, International journal of experimental pathology.