Phytochemical and Antibacterial studies of Seed extracts of Memecylon edule

The present study was carried out to analyse the preliminary phytochemical screening for ten principle bioactive compounds in Petroleum ether, chloroform, ethyl acetate and ethanol extracts of seeds of Memecylon edule collected from Potheri forest, Kattankulathur in Tamilnadu. Chloroform and ethyl acetate extracts of seeds of Memecylon edule were also investigated against ten bacteria using disc diffusion method. Preliminary phytochemical screening revealed the presence of Alkaloids, Triterpenes, Flavonoids and saponins. The maximum activity was observed in chloroform extract against Bacillus subtilis with zone of inhibition (15mm) and minimum activity was observed in ethyl acetate extract against Yersinia enterocolitica and Vibrio cholera at inhibition range was observed (10mm). The results suggest ethyl acetate and chloroform extracts of this plant with moderent antibacterial activity and secondary metabolites of this plant used for wound healing property and other forms of bacterial infections.

[1]  A. Nahrstedt,et al.  Anti-inflammatory, analgesic and wound healing activities of the leaves of Memecylon edule Roxb. , 2009, Journal of ethnopharmacology.

[2]  S. K. Singh,et al.  Dispelling the myth of tropical dry evergreen forests of India. Commentary , 2007 .

[3]  S. Chanda,et al.  Antibacterial Activity of Some Selected Indian Medicinal Flora , 2005 .

[4]  V. Rai,et al.  Antimicrobial activity of Memecylon malabaricum leaves. , 2004, Fitoterapia.

[5]  Ö. Erdoğrul,et al.  Antimicrobial Activities of Various Medicinal and Commercial Plant Extracts , 2003 .

[6]  Ö. Erdoğrul.  Antibacterial Activities of Some Plant Extracts Used in Folk Medicine , 2002 .

[7]  S. Renner,et al.  Molecular phylogenetics of Melastomataceae and Memecylaceae: implications for character evolution. , 2001, American journal of botany.

[8]  I. Ahmad,et al.  Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. , 2001, Journal of ethnopharmacology.

[9]  S. Jantová,et al.  Antibacterial activity of plant extracts from the families Fabaceae, Oleaceae, Philadelphaceae, Rosaceae and Staphyleaceae , 2000, Phytotherapy research : PTR.

[10]  G. G. Nascimento,et al.  Antibacterial activity of plant extracts and phytochemicals on antibiotic-resistant bacteria , 2000 .

[11]  N. Didry,et al.  Antimicrobial activity of aerial parts of Drosera peltata Smith on oral bacteria. , 1998, Journal of ethnopharmacology.

[12]  S. Buchmann,et al.  Anthecology of Mouriri myrtilloides (Melastomataceae: Memecyleae), an Oil Flower in Panama , 1981 .

[13]  J. Harborne.  Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis , 1973 .

[14]  B. Evers.  Indian Medicinal Plants , 1875, The Indian medical gazette.