Classification of equinus in ambulatory children with cerebral palsy-discrimination between dynamic tightness and fixed contracture.

In this study a generalised dynamic neural network (GDNN) was designed to process gait analysis parameters to evaluate equinus deformity in ambulatory children with cerebral palsy. The aim was to differentiate dynamic calf muscle tightness from fixed muscle contracture. Patients underwent clinical examination and had instrumented gait analysis before evaluating their equinus under anaesthesia and muscle relaxation at the time of surgery to improve gait. The performance of the clinical examination, the subjective interpretation of gait analysis results, and the application of the neural network to assess ankle function were compared to the examination under anaesthesia. Evaluation of equinus by a Neural Network showed high sensitivity and specificity values with a likelihood ratio of +14.63. The results indicate that dynamic calf muscle tightness can be differentiated from fixed calf muscle contracture with considerable precision that might facilitate clinical decision-making.

[1]  R Baker,et al.  The variability of goniometric measurements in ambulatory children with spastic cerebral palsy. , 2000, Gait & posture.

[2]  M P Kadaba,et al.  Measurement of lower extremity kinematics during level walking , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[3]  B. Etnyre,et al.  Preoperative and postoperative assessment of surgical intervention for equinus gait in children with cerebral palsy. , 1993, Journal of pediatric orthopedics.

[4]  E. Zwick,et al.  Fixed and Dynamic Equinus in Cerebral Palsy: Evaluation of Ankle Function After Multilevel Surgery , 2001, Journal of pediatric orthopedics.

[5]  L. A. Koman,et al.  Botulinum toxin type a neuromuscular blockade in the treatment of equinus foot deformity in cerebral palsy: a multicenter, open-label clinical trial. , 2001, Pediatrics.

[6]  E. Zwick,et al.  The Baumann procedure for fixed contracture of the gastrosoleus in cerebral palsy , 2000 .

[7]  R. B. Davis,et al.  Gait characterization via dynamic joint stiffness , 1996 .

[8]  Herbert Witte,et al.  Learning continuous trajectories in recurrent neural networks with time-dependent weights , 1999, IEEE Trans. Neural Networks.

[9]  Herbert Witte,et al.  Initial state training procedure improves dynamic recurrent networks with time-dependent weights , 2001, IEEE Trans. Neural Networks.

[10]  N. Allington,et al.  Ankle Joint Range of Motion Measurements in Spastic Cerebral Palsy Children: Intraobserver and Interobserver Reliability and Reproducibility of Goniometry and Visual Estimation , 2002, Journal of pediatric orthopedics. Part B.

[11]  D. Yngve,et al.  Vulpius and Z-lengthening. , 1996, Journal of pediatric orthopedics.

[12]  Keinosuke Fukunaga,et al.  Introduction to Statistical Pattern Recognition , 1972 .

[13]  S. James Contractures in orthopaedic and neurological conditions: a review of causes and treatment , 2001, Disability and rehabilitation.

[14]  J. Perry Kinesiology of lower extremity bracing. , 1974, Clinical orthopaedics and related research.

[15]  A. Cosgrove,et al.  Botulinum toxin A compared with stretching casts in the treatment of spastic equinus: a randomised prospective trial. , 1998, Journal of pediatric orthopedics.

[16]  James R. Gage,et al.  Gait Analysis: Principles and Applications , 1995 .

[17]  Yoshiyasu Takefuji,et al.  Parallel algorithms for finding a near-maximum independent set of a circle graph , 1990, IEEE Trans. Neural Networks.

[18]  Jocelyn Sietsma,et al.  Creating artificial neural networks that generalize , 1991, Neural Networks.

[19]  J. R. Gage The clinical use of kinetics for evaluation of pathologic gait in cerebral palsy. , 1994, Instructional course lectures.

[20]  K R Kaufman,et al.  Double-blind study of botulinum A toxin injections into the gastrocnemius muscle in patients with cerebral palsy. , 1999, Gait & posture.

[21]  H. Waddy,et al.  Botulinum toxin A versus fixed cast stretching for dynamic calf tightness in cerebral palsy , 1999, Journal of paediatrics and child health.

[22]  R. Boyd,et al.  Biomechanical transformation of the gastroc‐soleus muscle with botulinum toxin A in children with cerebral palsy , 2000, Developmental medicine and child neurology.

[23]  D. Antonelli,et al.  Gait analysis of the triceps surae in cerebral palsy. A preoperative and postoperative clinical and electromyographic study. , 1974, The Journal of bone and joint surgery. American volume.

[24]  G. Guyatt,et al.  Users' Guides to the Medical Literature: III. How to Use an Article About a Diagnostic Test: B. What Are the Results and Will They Help Me In Caring for My Patients? , 1994 .

[25]  J. Davids,et al.  Voluntary (normal) versus obligatory (cerebral palsy) toe-walking in children: a kinematic, kinetic, and electromyographic analysis. , 1999, Journal of pediatric orthopedics.

[26]  Ann Johnson,et al.  Prevalence and characteristics of children with cerebral palsy in Europe , 2002 .

[27]  J. Watt,et al.  A PROSPECTIVE STUDY OF INHIBITIVE CASTING AS AN ADJUNCT TO PHYSIOTHERAPY FOR CEREBRAL‐PALSIED CHILDREN , 1986, Developmental medicine and child neurology.

[28]  Rupert G. Miller The jackknife-a review , 1974 .

[29]  E. Zwick,et al.  Intrasubject repeatability of gait analysis data in normal and spastic children. , 2000, Clinical biomechanics.

[30]  J. Gage,et al.  Gait analysis: principle and applications with emphasis on its use in cerebral palsy. , 1996, Instructional course lectures.

[31]  R. Gerkin,et al.  The likelihood ratio as one of--if not the most important--operating characteristic of a diagnostic test. , 2003, Journal of general internal medicine.

[32]  S. Õunpuu,et al.  Kinematic and Kinetic Evaluation of the Ankle After Lengthening of the Gastrocnemius Fascia in Children with Cerebral Palsy , 1993, Journal of pediatric orthopedics.

[33]  Robert Tibshirani,et al.  A Comparison of Some Error Estimates for Neural Network Models , 1996, Neural Computation.

[34]  H. Graham,et al.  Lengthening of the calcaneal tendon in spastic hemiplegia by the White slide technique. A long-term review. , 1988, The Journal of bone and joint surgery. British volume.

[35]  R. Tibshirani,et al.  An introduction to the bootstrap , 1993 .

[36]  Richard W. Bohannon,et al.  Interrater reliability of a modified Ashworth scale of muscle spasticity. , 1987, Physical therapy.

[37]  G. Guyatt,et al.  Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. , 1994, JAMA.

[38]  Barak A. Pearlmutter Learning state space trajectories in recurrent neural networks : a preliminary report. , 1988 .

[39]  R. Rosenthal,et al.  The Use of Orthotics in Foot and Ankle Problems in Cerebral Palsy , 1984, Foot & ankle.

[40]  R. V. Dooren,et al.  A Chebyshev technique for solving nonlinear optimal control problems , 1988 .

[41]  H. Witte,et al.  Identification of hemifield single trial PVEP on the basis of generalized dynamic neural network classifiers , 1999, Clinical Neurophysiology.

[42]  G. Tardieu,et al.  [Research on a technic for measurement of spasticity]. , 1954, Revue neurologique.