Thymidylate synthase and dihydrofolate reductase expression in non-small cell lung carcinoma: the association with treatment efficacy of pemetrexed.
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Jou-Wei Lin | Chong-Jen Yu | Jin-Yuan Shih | Yih-Leong Chang | J. Shih | Pan‐Chyr Yang | Chong-Jen Yu | Pan-Chyr Yang | Yih-Leong Chang | Kuan-Yu Chen | Chih-Hsin Yang | Jou-Wei Lin | Chung-Yu Chen | Chung-Yu Chen | Chih‐Hsin Yang | Kuan-Yu Chen
[1] H. Uramoto,et al. TS, DHFR and GARFT expression in non-squamous cell carcinoma of NSCLC and malignant pleural mesothelioma patients treated with pemetrexed. , 2010, Anticancer research.
[2] J. Ahn,et al. The efficacy of pemetrexed as a third- or fourth-line therapy and the significance of thymidylate synthase expression in patients with advanced non-small cell lung cancer. , 2010, Lung cancer.
[3] Wancai Yang,et al. Genetic Determinants of Pemetrexed Responsiveness and Nonresponsiveness in Non-small Cell Lung Cancer Cells , 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[4] D. Gandara,et al. Histology- and gender-related associations of ERCC1, RRM1, and TS biomarkers in 1,802 patients with NSCLC: Implications for therapy. , 2010 .
[5] G. Scagliotti,et al. Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[6] K. Öhrling,et al. Prognostic and predictive value of thymidylate synthase expression in primary colorectal cancer. , 2010, Anticancer research.
[7] Thomas J. Smith,et al. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] J. Bertino,et al. Cancer research: from folate antagonism to molecular targets. , 2009, Best practice & research. Clinical haematology.
[9] G. Scagliotti,et al. The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. , 2009, The oncologist.
[10] X. Qian,et al. Predictive value of thymidylate synthase expression in advanced colorectal cancer patients receiving fluoropyrimidine‐based chemotherapy: Evidence from 24 studies , 2008, International journal of cancer.
[11] Johan Vansteenkiste,et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[12] E. Giovannetti,et al. Molecular Mechanisms Underlying the Synergistic Interaction of Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, with the Multitargeted Antifolate Pemetrexed in Non-Small-Cell Lung Cancer Cells , 2008, Molecular Pharmacology.
[13] A. Jemal,et al. Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.
[14] A. Tangoku,et al. Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase expression in tumor tissue, regarding the efficacy of postoperatively administered UFT (tegafur+uracil) in patients with non-small cell lung cancer. , 2007, Anticancer research.
[15] G. Scagliotti,et al. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase , 2006, Cancer.
[16] J. Walling. From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates , 2006, Investigational new drugs.
[17] P. Bunn,et al. Clinical activity of pemetrexed: a multitargeted antifolate anticancer agent. , 2005, Future oncology.
[18] Elisa Giovannetti,et al. Cellular and Pharmacogenetics Foundation of Synergistic Interaction of Pemetrexed and Gemcitabine in Human Non–Small-Cell Lung Cancer Cells , 2005, Molecular Pharmacology.
[19] R. Haba,et al. Clinical application of biological markers for treatments of resectable non-small-cell lung cancers , 2005, British Journal of Cancer.
[20] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[21] Patricia L. Harris,et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.
[22] Miklos Pless,et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[23] Thomas J. Smith,et al. American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] John J McGuire,et al. Anticancer antifolates: current status and future directions. , 2003, Current pharmaceutical design.
[25] G. Peters,et al. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. , 2003, Biochemical pharmacology.
[26] S. Miyoshi,et al. New prognostic indicator for non‐small‐cell lung cancer, quantitation of thymidylate synthase by real‐time reverse transcription polymerase chain reaction , 2003, International journal of cancer.
[27] Debabrata Banerjee,et al. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase. , 2002, Biochimica et biophysica acta.
[28] M. Fukushima,et al. Prognostic value of thymidylate synthase expression in patients with p-stage I adenocarcinoma of the lung. , 2002, Lung cancer.
[29] M. Fukushima,et al. Intratumoral expression of thymidylate synthase and dihydropyrimidine dehydrogenase in non-small cell lung cancer patients treated with 5-FU-based chemotherapy. , 2000, International journal of oncology.
[30] M. van Glabbeke,et al. New guidelines to evaluate the response to treatment in solid tumors , 2000, Journal of the National Cancer Institute.
[31] H. Miyachi,et al. Cellular and molecular mechanisms of resistance to antifolate drugs: new analogues and approaches to overcome the resistance. , 1997, International journal of hematology.
[32] C. Mountain,et al. Revisions in the International System for Staging Lung Cancer. , 1997, Chest.
[33] R M Schultz,et al. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. , 1997, Cancer research.
[34] O. Brodin,et al. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials , 1995 .
[35] J. Maizel,et al. The functional human dihydrofolate reductase gene. , 1984, The Journal of biological chemistry.
[36] M. Joerger,et al. The role of pemetrexed in advanced non small-cell lung cancer: special focus on pharmacology and mechanism of action. , 2010, Current drug targets.
[37] M. Fukushima,et al. A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance , 1998, Cancer.
[38] S. Groshen,et al. Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] M. Waltham,et al. Molecular mechanisms of resistance to antifolates, a review. , 1995, Acta biochimica Polonica.