Correlation and prediction of a large blood-brain distribution data set--an LFER study.
暂无分享,去创建一个
J. Platts | A. Hersey | D. Butina | M. Abraham | M H Abraham | A Hersey | Y. H. Zhao | D Butina | J A Platts | Y H Zhao | L Ijaz | L. Ijaz
[1] Juan M. Luco,et al. Prediction of the Brain-Blood Distribution of a Large Set of Drugs from Structurally Derived Descriptors Using Partial Least-Squares (PLS) Modeling , 1999, J. Chem. Inf. Comput. Sci..
[2] Harpreet S. Chadha,et al. Hydrogen bonding. 33. Factors that influence the distribution of solutes between blood and brain. , 1994, Journal of pharmaceutical sciences.
[3] J. Taskinen,et al. Relationship between immobilised artificial membrane chromatographic retention and the brain penetration of structurally diverse drugs. , 1997, Journal of pharmaceutical and biomedical analysis.
[4] Y. Dambisya,et al. Dispositional study of opioids in mice pretreated with sympathomimetic agents , 1992, The Journal of pharmacy and pharmacology.
[5] S. Okuyama,et al. The mode of action of analgesic drugs in adjuvant arthritic rats as an experimental model of chronic inflammatory pain: possible central analgesic action of acidic nonsteroidal antiinflammatory drugs. , 1984, Japanese journal of pharmacology.
[6] E Sakurai,et al. Effect of concanavalin A on the aspirin concentration and distribution in the brain and plasma of rats. , 1986, Journal of pharmacobio-dynamics.
[7] D. E. Clark,et al. Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration. , 1999, Journal of pharmaceutical sciences.
[8] W H Oldendorf,et al. Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection. , 1971, The American journal of physiology.
[9] S. Urien,et al. Drug Binding in Plasma , 1994, Clinical pharmacokinetics.
[10] C. Hansch,et al. The parabolic dependence of drug action upon lipophilic character as revealed by a study of hypnotics. , 1968, Journal of medicinal chemistry.
[11] M. Feher,et al. A simple model for the prediction of blood-brain partitioning. , 2000, International journal of pharmaceutics.
[12] W H Oldendorf,et al. Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. , 1970, Brain research.
[13] R Griffiths,et al. Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists. , 1988, Journal of medicinal chemistry.
[14] M Danhof,et al. Differences in intrinsic efficacy of benzodiazepines are reflected in their concentration‐EEG effect relationship , 1992, British journal of pharmacology.
[15] Bruce M. Cohen,et al. Blood to brain distribution of neuroleptics , 1987, Psychiatry Research.
[16] Harpreet S. Chadha,et al. Molecular Factors Influencing Drug Transfer across the Blood‐Brain Barrier , 1997, The Journal of pharmacy and pharmacology.
[17] R Griffiths,et al. Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1‐receptor antagonist with negligible ability to penetrate the central nervous system , 1986, British journal of pharmacology.
[18] F. Lombardo,et al. Computation of brain-blood partitioning of organic solutes via free energy calculations. , 1996, Journal of medicinal chemistry.
[19] MARCEL H. BICKEL,et al. Drug distribution as a function of binding competition. Experiments with the distribution dialysis technique , 1980, The Journal of pharmacy and pharmacology.
[20] Meindert Danhof,et al. Critical factors of intracerebral microdialysis as a technique to determined the pharmacokinetics of drugs in rat brain , 1994, Brain Research.
[21] György M. Keserü,et al. High-throughput prediction of blood-brain partitioning: a thermodynamic approach. , 2001, Journal of chemical information and computer sciences.
[22] I. Pollard,et al. Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine. , 1993, Brain research. Developmental brain research.
[23] David J. Begley,et al. The Blood-brain Barrier and Drug Delivery to the CNS , 2000 .
[24] M. Yazdanian,et al. In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents. , 1998, Journal of pharmaceutical sciences.
[25] Michael H. Abraham,et al. Hydrogen bonding. Part 34. The factors that influence the solubility of gases and vapours in water at 298 K, and a new method for its determination , 1994 .
[26] James A. Platts,et al. Estimation of Molecular Linear Free Energy Relation Descriptors Using a Group Contribution Approach , 1999, J. Chem. Inf. Comput. Sci..
[27] G Beck,et al. Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors. , 2001, Journal of pharmaceutical sciences.
[28] U Norinder,et al. Theoretical calculation and prediction of brain-blood partitioning of organic solutes using MolSurf parametrization and PLS statistics. , 1998, Journal of pharmaceutical sciences.
[29] James A. Platts,et al. Estimation of Molecular Linear Free Energy Relationship Descriptors by a Group Contribution Approach. 2. Prediction of Partition Coefficients , 2000, J. Chem. Inf. Comput. Sci..
[30] Michael H. Abraham,et al. Physicochemical analysis of the factors governing distribution of solutes between blood and brain , 1994 .
[31] Y. Ishihama,et al. Characterization of lipophilicity scales using vectors from solvation energy descriptors. , 1999, Journal of pharmaceutical sciences.
[32] Michael H. Abraham,et al. Hydrogen bonding part 46: a review of the correlation and prediction of transport properties by an lfer method: physicochemical properties, brain penetration and skin permeability , 1999 .
[33] G W Kunsman,et al. Tissue distribution of ibuprofen in a fatal overdose. , 1993, The American journal of forensic medicine and pathology.
[34] B Testa,et al. Predicting blood-brain barrier permeation from three-dimensional molecular structure. , 2000, Journal of medicinal chemistry.
[35] Bruce M. Cohen,et al. Drug distribution between blood and brain as a determinant of antipsychotic drug effects , 1992, Biological Psychiatry.
[36] Harpreet S. Chadha,et al. Hydrogen bonding. 32. An analysis of water-octanol and water-alkane partitioning and the delta log P parameter of seiler. , 1994, Journal of pharmaceutical sciences.
[37] G. Wahlström,et al. Reevaluation of potency and pharmacokinetic properties of some lipid-soluble barbiturates with an EEG-threshold method. , 2009, Acta pharmacologica et toxicologica.