O2 extraction during exercise determines training effect after cardiac rehabilitation in myocardial infarction.

Correlations between baseline hemodynamic and oximetric variables during an invasive exercise test and an improvement in peak oxygen uptake (peak VO2) after exercise training (ET) were examined in 20 patients who participated in a cardiac rehabilitation program after acute myocardial infarction (AMI). Peak VO2 significantly increased by 23 +/- 21% (p < 0.01) after ET and the improvement best correlated with the change in O2 extraction fraction ([arterial O2 content-venous O2 content]/arterial O2 content) during an exercise testbefore ET (r = -0.61, p<0.01). Exercise capacity was improved to a greater extent by ET in patients with a smaller increase in O2 extraction fraction during an exercise test before ET. Thus, O2 extraction fraction during an exercise test before ET may be a useful predictor of the improvement in exercise capacity after ET in post-AMI patients.

[1]  N. Aihara,et al.  Excessive ventilation after acute myocardial infarction and its improvement in 4 months. , 2001, Japanese circulation journal.

[2]  M. Kohzuki,et al.  Effects of a two-week, hospitalized phase II cardiac rehabilitation program on physical capacity, lipid profiles and psychological variables in patients with acute myocardial infarction. , 2001, Japanese circulation journal.

[3]  宮下 豊久.  Relation between exercise capacity and left ventricular systolic versus diastolic function during exercise in patients after myocardial infarction , 2001 .

[4]  A. Kitabatake,et al.  Metabolic abnormality of calf skeletal muscle is improved by localised muscle training without changes in blood flow in chronic heart failure , 1997, Heart.

[5]  C. Sylvén,et al.  Improved ventilation and decreased sympathetic stress in chronic heart failure patients following local endurance training with leg muscles. , 1997, Journal of cardiac failure.

[6]  T. Noakes,et al.  Predictors of exercise capacity and adaptability to training in patients with coronary artery disease. , 1997, Journal of cardiopulmonary rehabilitation.

[7]  P. Poole‐Wilson,et al.  The influence of muscle mass, strength, fatigability and blood flow on exercise capacity in cachectic and non-cachectic patients with chronic heart failure. , 1997, European heart journal.

[8]  M. Heldal,et al.  Simple clinical data are useful in predicting effect of exercise training after myocardial infarction. , 1996, European heart journal.

[9]  P. Poole‐Wilson,et al.  Exercise limitation in chronic heart failure: central role of the periphery. , 1996, Journal of the American College of Cardiology.

[10]  J. Wilson,et al.  Circulatory status and response to cardiac rehabilitation in patients with heart failure. , 1996, Circulation.

[11]  J. Myers,et al.  Benefit of Selective Respiratory Muscle Training on Exercise Capacity in Patients With Chronic Congestive Heart Failure , 1996 .

[12]  D. Mancini,et al.  Benefit of selective respiratory muscle training on exercise capacity in patients with chronic congestive heart failure. , 1995, Circulation.

[13]  C. Lavie,et al.  Benefits of Cardiac Rehabilitation and Exercise Training in Secondary Coronary Prevention in the Elderly , 1994 .

[14]  G. Radda,et al.  Physical training improves skeletal muscle metabolism in patients with chronic heart failure. , 1993, Journal of the American College of Cardiology.

[15]  C. Lavie,et al.  Psychological Adaptation to Cardiovascular Disease , 1993 .

[16]  P. Ades,et al.  Cardiac rehabilitation participation predicts lower rehospitalization costs. , 1992, American heart journal.

[17]  Y. Okano,et al.  Cardiopulmonary Responses and Blood Flow Distribution during Exercise in Patients with Left Ventricular Dysfunction , 1992 .

[18]  T. L. Hudson,et al.  Skeletal muscle response to exercise training in congestive heart failure. , 1990, The Journal of clinical investigation.

[19]  C. Lavie,et al.  Cardiovascular rehabilitation: status, 1990. , 1990, Mayo Clinic proceedings.

[20]  H. Duivenvoorden,et al.  Success and failure of exercise training after myocardial infarction: is the outcome predictable? , 1990, Journal of the American College of Cardiology.

[21]  J. Buring,et al.  An overview of randomized trials of rehabilitation with exercise after myocardial infarction. , 1989, Circulation.

[22]  R. W. Brower,et al.  Value of predischarge data for the prediction of exercise capacity after cardiac rehabilitation in patients with recent myocardial infarction. , 1987, European heart journal.

[23]  V. Froelicher,et al.  Use of clinical data in predicting improvement in exercise capacity after cardiac rehabilitation. , 1985, Journal of the American College of Cardiology.

[24]  T. Levine,et al.  Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure. , 1981, The American journal of cardiology.

[25]  M. Sanmarco,et al.  Long-term effects of physical training on coronary patients with impaired ventricular function. , 1979, Circulation.

[26]  H. Dodge,et al.  An Angiocardiographic Method for Directly Determining Left Ventricular Stroke Volume in Man , 1962, Circulation research.