CCR6: a biomarker for Alzheimer's-like disease in a triple transgenic mouse model.
暂无分享,去创建一个
J. Quinn | A. Vandenbark | H. Offner | Joseph F Quinn | S. Subramanian | Arthur A Vandenbark | Halina Offner | Sandhya Subramanian | Patricia Ayala | Teri L Wadsworth | Christopher J Harris | T. Wadsworth | Patricia Ayala | Christopher J. Harris
[1] Masanori Kato,et al. Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases , 2002, Journal of Neuroimmunology.
[2] S. Barger,et al. Interleukin-1 Mediates Pathological Effects of Microglia on Tau Phosphorylation and on Synaptophysin Synthesis in Cortical Neurons through a p38-MAPK Pathway , 2003, The Journal of Neuroscience.
[3] C. Martínez-A,et al. CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses. , 2005, Blood.
[4] Sue-Jane Lin,et al. Programmed death-1 (PD-1) defines a transient and dysfunctional oligoclonal T cell population in acute homeostatic proliferation , 2007, The Journal of experimental medicine.
[5] S. Lipton,et al. Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. , 1999, Stroke.
[6] P. Marrack,et al. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties , 2008, Proceedings of the National Academy of Sciences.
[7] I. Messaoudi,et al. Age-Related CD8+ T Cell Clonal Expansions Express Elevated Levels of CD122 and CD127 and Display Defects in Perceiving Homeostatic Signals1 , 2006, The Journal of Immunology.
[8] G. Annoni,et al. Increased plasma levels of interleukin-1, interleukin-6 and α-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? , 2000, Journal of Neuroimmunology.
[9] K. Pennypacker,et al. The spleen contributes to stroke‐induced neurodegeneration , 2008, Journal of neuroscience research.
[10] Soo‐Young Choi,et al. Oligonucleotide-based Analysis of Differentially Expressed Genes in Hippocampus of Transgenic Mice Expressing NSE-controlled APPsw , 2006, Neurochemical Research.
[11] L. Frölich,et al. Apoptosis of CD4+ T and natural killer cells in Alzheimer's disease. , 2006, Pharmacopsychiatry.
[12] M. Donia,et al. Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells. , 2009, Journal of autoimmunity.
[13] F. LaFerla,et al. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice , 2005, Journal of Neuroinflammation.
[14] R Brookmeyer,et al. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. , 1998, American journal of public health.
[15] F. LaFerla,et al. Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. , 2008, The American journal of pathology.
[16] U. Hanisch,et al. Microglia as a source and target of cytokines , 2002, Glia.
[17] R. Rabin,et al. CC-Chemokine Receptor 6 Is Expressed on Diverse Memory Subsets of T Cells and Determines Responsiveness to Macrophage Inflammatory Protein 3α , 1999, The Journal of Immunology.
[18] Pawan Kumar,et al. Role of Macrophage Inflammatory Protein-3α and Its Ligand CCR6 in Rheumatoid Arthritis , 2003, Laboratory Investigation.
[19] S. Lira,et al. Attenuation of Allergen-Induced Responses in CCR6−/− Mice Is Dependent upon Altered Pulmonary T Lymphocyte Activation , 2005, The Journal of Immunology.
[20] X. Chen,et al. RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease , 1996, Nature.
[21] Jae Woong Lee,et al. Journal of Neuroinflammation Neuro-inflammation Induced by Lipopolysaccharide Causes Cognitive Impairment through Enhancement of Beta-amyloid Generation , 2022 .
[22] J. Bluestone,et al. Ly-6C is a marker of memory CD8+ T cells. , 1995, Journal of immunology.
[23] R. Tibshirani,et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins , 2007, Nature Medicine.
[24] D. Ethell,et al. Aβ-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS , 2009, Neurobiology of Disease.
[25] P. Grammas,et al. Inflammatory factors are elevated in brain microvessels in Alzheimer’s disease , 2001, Neurobiology of Aging.
[26] R. Kayed,et al. Novel Aβ peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease , 2005, Journal of Neuroinflammation.
[27] M. Weinand,et al. Amyloid-β Induces Chemokine Secretion and Monocyte Migration across a Human Blood-Brain Barrier Model , 1998, Molecular medicine.
[28] E. Scarpini,et al. Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with β-amyloid[25–35] , 1999, Journal of Neuroimmunology.
[29] C. Caltagirone,et al. Increased pro-inflammatory response by dendritic cells from patients with Alzheimer's disease. , 2010, Journal of Alzheimer's disease : JAD.
[30] S. Barger. Vascular consequences of passive Aβ immunization for Alzheimer's disease. Is avoidance of "malactivation" of microglia enough? , 2005, Journal of Neuroinflammation.
[31] B. Rocha,et al. The Tower of Babel of CD8+ T‐cell memory: known facts, deserted roads, muddy waters, and possible dead ends , 2006, Immunological reviews.
[32] D. Flaherty,et al. Age dependent increase in early resistance of mice to Mycobacterium tuberculosis is associated with an increase in CD8 T cells that are capable of antigen independent IFN-γ production , 2006, Experimental Gerontology.
[33] P. Mcgeer,et al. Inflammation in transgenic mouse models of neurodegenerative disorders. , 2010, Biochimica et biophysica acta.
[34] H. Offner,et al. Male SJL mice do not relapse after induction of EAE with PLP 139–151 , 1996, Journal of neuroscience research.
[35] L. Frölich,et al. Increased T-cell Reactivity and Elevated Levels of CD8+ Memory T-cells in Alzheimer’s Disease-patients and T-cell Hyporeactivity in an Alzheimer’s Disease-mouse Model: Implications for Immunotherapy , 2007, NeuroMolecular Medicine.
[36] C. Lyketsos,et al. IL-6 release by LPS-stimulated peripheral blood mononuclear cells as a potential biomarker in Alzheimer's disease , 2009, International Psychogeriatrics.
[37] Paul S. Aisen,et al. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model , 2008, Brain Research.
[38] F. LaFerla,et al. Profile for Amyloid-β and Tau Expression in Primary Cortical Cultures from 3xTg-AD Mice , 2010, Cellular and Molecular Neurobiology.
[39] D. Ethell,et al. Aβ-specific T-cells reverse cognitive decline and synaptic loss in Alzheimer's mice , 2006, Neurobiology of Disease.
[40] O. Simell,et al. Ly-6C regulates endothelial adhesion and homing of CD8(+) T cells by activating integrin-dependent adhesion pathways. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[41] S. Jalkanen,et al. Ly6C Induces Clustering of LFA-1 (CD11a/CD18) and Is Involved in Subtype-Specific Adhesion of CD8 T Cells 1 , 2003, The Journal of Immunology.
[42] T. Schumacher,et al. Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis , 2009, Proceedings of the National Academy of Sciences.
[43] M. Mattson,et al. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Intracellular Aβ and Synaptic Dysfunction , 2003, Neuron.
[44] F. Barone,et al. Reperfusion following focal stroke hastens inflammation and resolution of ischemic injured tissue , 1994, Brain Research Bulletin.
[45] K. Moore,et al. CD36 Mediates the Innate Host Response to β-Amyloid , 2003, The Journal of experimental medicine.
[46] S. Lira,et al. CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC , 2010, European journal of immunology.