SOCS2 protects against chemical-induced hepatocellular carcinoma progression by modulating inflammation and cell proliferation in the liver.
暂无分享,去创建一个
J. J. Cabrera-Galván | C. Melián | B. Guerra | L. Fernández-Pérez | Carlota Recio | Y. Brito-Casillas | Miguel Guerra-Rodríguez | Haidée Aranda-Tavío | MaríaSol Martínez-Martín | Mercedes de Mirecki-Garrido | Eduardo Araujo | David Pérez-Rodríguez
[1] R. Masuzaki,et al. Suppressors of Cytokine Signaling and Hepatocellular Carcinoma , 2022, Cancers.
[2] Clifford Liongue,et al. SOCS Proteins in Immunity, Inflammatory Diseases, and Immune-Related Cancer , 2021, Frontiers in Medicine.
[3] Zhangzhi Zhu,et al. Identification of potential crucial genes associated with the pathogenesis and prognosis of liver hepatocellular carcinoma , 2020, Journal of Clinical Pathology.
[4] S. Ramanathan,et al. Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma , 2020, BMC Cancer.
[5] B. Carr,et al. Inflammatory Mechanisms of HCC Development , 2020, Cancers.
[6] G. Ferbeyre,et al. STAT3 and STAT5 Activation in Solid Cancers , 2019, Cancers.
[7] P. Sutphin,et al. Staging systems of hepatocellular carcinoma: A review , 2018, Indian Journal of Gastroenterology.
[8] D. Frank,et al. Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors. , 2017, Trends in cancer.
[9] Stefan Rose-John,et al. IL-6 pathway in the liver: From physiopathology to therapy. , 2016, Journal of hepatology.
[10] L. Terracciano,et al. Histopathology of hepatocellular carcinoma. , 2014, World journal of gastroenterology.
[11] S. Haan,et al. Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer , 2014, British Journal of Cancer.
[12] Alisha M. Mendonsa,et al. Hepatocellular Proliferation Correlates with Inflammatory Cell and Cytokine Changes in a Murine Model of Nonalchoholic Fatty Liver Disease , 2013, PloS one.
[13] Y. Tu,et al. Reduced expression of SOCS2 and SOCS6 in hepatocellular carcinoma correlates with aggressive tumor progression and poor prognosis , 2013, Molecular and Cellular Biochemistry.
[14] G. Norstedt,et al. SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high‐fat‐diet‐fed mice , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] G. Trinchieri. Cancer and inflammation: an old intuition with rapidly evolving new concepts. , 2012, Annual review of immunology.
[16] M. Karin,et al. Tumor promotion via injury- and death-induced inflammation. , 2011, Immunity.
[17] Kuen-Feng Chen,et al. Activation of Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Mediates Acquired Resistance to Sorafenib in Hepatocellular Carcinoma Cells , 2011, Journal of Pharmacology and Experimental Therapeutics.
[18] Chiun Hsu,et al. Molecular targeted therapy for advanced hepatocellular carcinoma: current status and future perspectives , 2010, Journal of Gastroenterology.
[19] P. Lund,et al. Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/+) tumorigenesis and activator protein-1 activation. , 2010, The American journal of pathology.
[20] T. Okanoue,et al. Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice , 2010, Laboratory Investigation.
[21] F. Heindryckx,et al. Experimental mouse models for hepatocellular carcinoma research , 2009, International journal of experimental pathology.
[22] L. Hennighausen,et al. Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-β and STAT3 activation , 2009, The Journal of experimental medicine.
[23] S. Friedman,et al. Experimental models of hepatocellular carcinoma. , 2008, Journal of hepatology.
[24] F. Révillion,et al. Favorable prognostic value of SOCS2 and IGF-I in breast cancer , 2007, BMC Cancer.
[25] Masato Kubo,et al. SOCS proteins, cytokine signalling and immune regulation , 2007, Nature Reviews Immunology.
[26] Tania Nolan,et al. Quantification of mRNA using real-time RT-PCR , 2006, Nature Protocols.
[27] S. Thorgeirsson,et al. Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence , 2006, Hepatology.
[28] D. Santini,et al. Suppressor of cytokine signalling 2 (SOCS-2) expression in breast carcinoma , 2005, Journal of Clinical Pathology.
[29] Carmen Z. Michaylira,et al. Suppressor of cytokine signaling-2 modulates the fibrogenic actions of GH and IGF-I in intestinal mesenchymal cells. , 2005, American journal of physiology. Gastrointestinal and liver physiology.
[30] Michael Karin,et al. IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis , 2005, Cell.
[31] Eric B Haura,et al. Mechanisms of Disease: insights into the emerging role of signal transducers and activators of transcription in cancer , 2005, Nature Clinical Practice Oncology.
[32] Michael Karin,et al. Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases , 2005, Cell.
[33] W. Alexander,et al. Gigantism in mice lacking suppressor of cytokine signalling-2 , 2000, Nature.
[34] K. Movahedi,et al. Tissue-resident versus monocyte-derived macrophages in the tumor microenvironment. , 2016, Biochimica et biophysica acta.
[35] S. Haan,et al. SOCS2: physiological and pathological functions. , 2016, Frontiers in bioscience.
[36] G. Jenster,et al. SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer. , 2014, Carcinogenesis.
[37] A. Jemal,et al. Global Cancer Statistics , 2011 .