Endoglin based in vivo near-infrared fluorescence imaging of tumor models in mice using activatable liposomes.
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I. Hilger | R. Kontermann | A. Fahr | F. Steiniger | U. Teichgraeber | R. Rüger | F. Tansi | Ansgar M. Kollmeier | Markus Rabenhold
[1] I. Hilger,et al. Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously. , 2017, Acta biomaterialia.
[2] I. Hilger,et al. A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs , 2017, BMC Biotechnology.
[3] Ingrid Hilger,et al. Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases. , 2016, Biomaterials.
[4] I. Hilger,et al. Fluorescence-quenching of a liposomal-encapsulated near-infrared fluorophore as a tool for in vivo optical imaging. , 2015, Journal of visualized experiments : JoVE.
[5] G. Winter,et al. Thermosensitive liposomal drug delivery systems: state of the art review , 2014, International journal of nanomedicine.
[6] I. Hilger,et al. In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes. , 2014, Journal of controlled release : official journal of the Controlled Release Society.
[7] M. Letarte,et al. Review: the enigmatic role of endoglin in the placenta. , 2014, Placenta.
[8] W. Kaiser,et al. Liposomal encapsulation of a near-infrared fluorophore enhances fluorescence quenching and reliable whole body optical imaging upon activation in vivo. , 2013, Small.
[9] N. Oku,et al. Enhanced Active Targeting via Cooperative Binding of Ligands on Liposomes to Target Receptors , 2013, PloS one.
[10] F. Salvatore,et al. Cytometric and biochemical characterization of human breast cancer cells reveals heterogeneous myoepithelial phenotypes , 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.
[11] Meng Yang,et al. Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha. , 2012, Bioconjugate chemistry.
[12] H. Shmeeda,et al. Pharmacological basis of pegylated liposomal doxorubicin: impact on cancer therapy. , 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[13] Viness Pillay,et al. A Review on Composite Liposomal Technologies for Specialized Drug Delivery , 2011, Journal of drug delivery.
[14] J. López-Novoa,et al. The emerging role of TGF-beta superfamily coreceptors in cancer. , 2009, Biochimica et biophysica acta.
[15] P. Choyke,et al. H-type dimer formation of fluorophores: a mechanism for activatable, in vivo optical molecular imaging. , 2009, ACS chemical biology.
[16] R. Kontermann,et al. Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice. , 2008, Journal of immunological methods.
[17] George Zonios,et al. Melanin optical properties provide evidence for chemical and structural disorder in vivo. , 2008, Optics express.
[18] L. Ellis,et al. Endoglin (CD105): A Marker of Tumor Vasculature and Potential Target for Therapy , 2008, Clinical Cancer Research.
[19] T. Allen,et al. Targeted delivery of anti-CD19 liposomal doxorubicin in B-cell lymphoma: a comparison of whole monoclonal antibody, Fab' fragments and single chain Fv. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[20] A. Fahr,et al. Drug delivery strategies for poorly water-soluble drugs , 2007, Expert opinion on drug delivery.
[21] R. Kontermann,et al. Improved Pharmacokinetics of Recombinant Bispecific Antibody Molecules by Fusion to Human Serum Albumin* , 2007, Journal of Biological Chemistry.
[22] W. Aird,et al. Vascular endocan is preferentially expressed in tumor endothelium. , 2006, Microvascular research.
[23] R. Kontermann,et al. Generation of immunoliposomes using recombinant single-chain Fv fragments bound to Ni-NTA-liposomes , 2005, Journal of drug targeting.
[24] R. Kontermann,et al. Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library. , 2004, Biochemical and biophysical research communications.
[25] S. O'dwyer,et al. Perfusion of 99Tcm‐labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target , 2004, International journal of cancer.
[26] R. M. Cook,et al. Intramolecular dimers: a new design strategy for fluorescence-quenched probes. , 2003, Chemistry.
[27] M. Maio,et al. Endoglin (CD105): a target for anti-angiogenetic cancer therapy. , 2003, Current drug targets.
[28] R. Brekken,et al. Strategies for vascular targeting in tumors , 2002, International journal of cancer.
[29] L. Zardi,et al. Lack of specificity of endoglin expression for tumor blood vessels , 2001, International journal of cancer.
[30] T. Allen,et al. In vitro and in vivo comparison of immunoliposomes made by conventional coupling techniques with those made by a new post-insertion approach. , 2001, Biochimica et biophysica acta.
[31] M. Maio,et al. Endoglin is a suitable target for efficient imaging of solid tumors: in vivo evidence in a canine mammary carcinoma model. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[32] Semi Kim,et al. Regulation of Angiogenesis in Vivo by Ligation of Integrin α5β1 with the Central Cell-Binding Domain of Fibronectin , 2000 .
[33] M. Barcos,et al. Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[34] E Biganzoli,et al. Vascular integrin alpha(v)beta3: a new prognostic indicator in breast cancer. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.
[35] E. Butcher,et al. Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand. , 1994, Gene.
[36] J. Healey,et al. Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[37] A. Ito,et al. Optical absorption and fluorescence spectroscopy studies of ground state melanin-cationic porphyrins complexes. , 1992, Biophysical chemistry.
[38] J. Denekamp,et al. Endothelial proliferation in tumours and normal tissues: continuous labelling studies. , 1984, British Journal of Cancer.
[39] G. Salzano,et al. Multifunctional Liposomes. , 2017, Methods in molecular biology.
[40] J. Feldman. A MATHEMATICAL MODEL FOR TUMOR VOLUME EVALUATION USING TWO-DIMENSIONS , 2010 .
[41] W. Aird. Molecular heterogeneity of tumor endothelium , 2008, Cell and Tissue Research.
[42] Vasilis Ntziachristos,et al. Shedding light onto live molecular targets , 2003, Nature Medicine.
[43] E. Moase,et al. Use of the post-insertion method for the formation of ligand-coupled liposomes. , 2002, Cellular & molecular biology letters.