论文信息 - Anti‐A1 in the Plasma of Platelet Concentrates Causing a Hemolytic Reaction

Anti‐A1 in the Plasma of Platelet Concentrates Causing a Hemolytic Reaction

A patient with acute leukemia who typed as AintB received 10 packs of platelets of group 0. Subsequent transfusion of A1B blood resulted in a hemolytic transfusion reaction. Anti‐A1 was detected in the serum and on the red blood cells of a post‐transfusion sample. This anti‐A1 reacted with the transfused A1B red blood cells and other A1 cells, but not with the patient's pretransfusion red blood cells. The plasma of the transfused platelet concentrates had a high titer of immune anti‐A.

[1] W. B. Lundberg,et al. Hemolytic transfusion reaction due to anti‐A , 2003, Transfusion.

[2] D. Weatherall,et al. Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore. , 1963, Blood.

[3] P. Mollison,et al. Relation Between Characteristics of Blood‐Group Antibodies in Vitro and Associated Patterns of Red‐Cell Destruction in Vivo , 1958, British journal of haematology.

[4] A. Chernoff,et al. Studies on abnormal hemoglobins. I. Their demonstration in sickle cell anemia and other hematologic disorders by means of alkali denaturation. , 1951, Blood.

[5] K. Boorman,et al. Some results of transfusion of blood to recipients with cold agglutinins. , 1946, British medical journal.