The function of Near Space Vehicle (NSV) in aerospace information system is analyzed in this paper firstly. Then the architecture of area information confrontation system based on NSV is presented aiming at achieving superiority in area information confrontation and the possible information confrontation mode is discussed. Finally the design of NSV information confrontation simulation system is put forward. This paper is of guiding significance for the effective utilize of near space as well as the development of NSV and its payload.