Zinc Homeostasis Alters Zinc Transporter Protein Expression in Vascular Endothelial and Smooth Muscle Cells

[1]  D. A. S. Vieira,et al.  Zinc nutritional status influences ZnT1 and ZIP4 gene expression in children with a high risk of zinc deficiency. , 2020, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

[2]  G. Maarman.  Pulmonary arterial hypertension and the potential roles of metallothioneins: A focused review , 2018, Life sciences.

[3]  J. Beltrame,et al.  Roles for endothelial zinc homeostasis in vascular physiology and coronary artery disease , 2018, Critical reviews in food science and nutrition.

[4]  M. Suico,et al.  Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells , 2017, EBioMedicine.

[5]  M. Provinciali,et al.  Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence , 2017, Experimental Gerontology.

[6]  W. Maret,et al.  Zinc in Cellular Regulation: The Nature and Significance of “Zinc Signals” , 2017, International journal of molecular sciences.

[7]  S. Hodge,et al.  The uncoupling of autophagy and zinc homeostasis in airway epithelial cells as a fundamental contributor to COPD. , 2017, American journal of physiology. Lung cellular and molecular physiology.

[8]  W. Maret,et al.  The Functions of Metamorphic Metallothioneins in Zinc and Copper Metabolism , 2017, International journal of molecular sciences.

[9]  A. Soliman,et al.  Serum zinc concentration in cystic fibrosis patients with CFTR I1234V mutation associated with pancreatic sufficiency , 2017, The clinical respiratory journal.

[10]  R. Zarivach,et al.  Zinc transport and the inhibition of the L-type calcium channel are two separable functions of ZnT-1. , 2017, Metallomics : integrated biometal science.

[11]  Takafumi Hara,et al.  Physiological roles of zinc transporters: molecular and genetic importance in zinc homeostasis , 2017, The Journal of Physiological Sciences.

[12]  V. Adam,et al.  Metallothionein as a Scavenger of Free Radicals - New Cardioprotective Therapeutic Agent or Initiator of Tumor Chemoresistance? , 2016, Current drug targets.

[13]  T. Kimura,et al.  Induction of metallothionein isoforms by copper diethyldithiocarbamate in cultured vascular endothelial cells. , 2016, The Journal of toxicological sciences.

[14]  S. Cockell,et al.  Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc. , 2016, Metallomics : integrated biometal science.

[15]  T. Kambe,et al.  The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism. , 2015, Physiological reviews.

[16]  G. Rutter,et al.  The zinc transporter, ZIP12, regulates the pulmonary vascular response to chronic hypoxia , 2015, Nature.

[17]  S. Hodge,et al.  Zinc and Zinc Transporters in Macrophages and Their Roles in Efferocytosis in COPD , 2014, PloS one.

[18]  Yoram Etzion,et al.  ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger. , 2014, Metallomics : integrated biometal science.

[19]  E. Weijers,et al.  Expression, Regulation and Function of Human Metallothioneins in Endothelial Cells , 2014, Journal of Vascular Research.

[20]  C. Suschek,et al.  Zinc regulates iNOS-derived nitric oxide formation in endothelial cells , 2014, Redox biology.

[21]  T. Kambe,et al.  Current understanding of ZIP and ZnT zinc transporters in human health and diseases , 2014, Cellular and Molecular Life Sciences.

[22]  C. Murgia,et al.  Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways , 2013, BioMetals.

[23]  C. Hill,et al.  Immunolocalization of NLRP3 Inflammasome in Normal Murine Airway Epithelium and Changes following Induction of Ovalbumin-Induced Airway Inflammation , 2012, Journal of allergy.

[24]  B. Seidel-Rogol,et al.  Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells , 2012, PloS one.

[25]  R. Ruffin,et al.  Sputum zinc concentration and clinical outcome in older asthmatics , 2011, Respirology.

[26]  L. McIntire,et al.  Endothelial metallothionein expression and intracellular free zinc levels are regulated by shear stress. , 2010, American journal of physiology. Cell physiology.

[27]  Levi A. Gheber,et al.  Molecular Basis for Zinc Transporter 1 Action as an Endogenous Inhibitor of L-type Calcium Channels* , 2009, The Journal of Biological Chemistry.

[28]  G. Perozzi,et al.  Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands. , 2009, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[29]  Julia E Cummings,et al.  The ubiquitous role of zinc in health and disease. , 2009, Journal of veterinary emergency and critical care.

[30]  David P. Wilson,et al.  Heterogeneity of L- and T-Channels in the Vasculature: Rationale for the Efficacy of Combined L- and T-Blockade , 2009, Hypertension.

[31]  J. Mathers,et al.  Mechanisms of mammalian zinc-regulated gene expression. , 2008, Biochemical Society transactions.

[32]  M. Cardelli,et al.  A novel Zip2 Gln/Arg/Leu codon 2 polymorphism is associated with carotid artery disease in aging. , 2008, Rejuvenation research.

[33]  C. Caruso,et al.  Involvement of −308 TNF-α and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients , 2006, Biogerontology.

[34]  I. Sekler,et al.  Silencing of ZnT-1 expression enhances heavy metal influx and toxicity , 2006, Journal of Molecular Medicine.

[35]  M. Yamakuchi,et al.  Regulation of Weibel-Palade body exocytosis. , 2005, Trends in cardiovascular medicine.

[36]  I. Sekler,et al.  A role for ZnT-1 in regulating cellular cation influx. , 2004, Biochemical and biophysical research communications.

[37]  A. Favier,et al.  Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. , 2004, Diabetes.

[38]  John G. Collard,et al.  Temporal and Spatial Modulation of Rho GTPases during in Vitro Formation of Capillary Vascular Network , 2003, Journal of Biological Chemistry.

[39]  M. Popp,et al.  A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[40]  D. Giedroc,et al.  Metal response element (MRE)-binding transcription factor-1 (MTF-1): structure, function, and regulation. , 2001, Antioxidants & redox signaling.

[41]  G. Andrews,et al.  The Transcription Factor MTF-1 Mediates Metal Regulation of the Mouse ZnT1 Gene* , 2000, The Journal of Biological Chemistry.

[42]  D. Eide,et al.  Functional Expression of the Human hZIP2 Zinc Transporter* , 2000, The Journal of Biological Chemistry.

[43]  R. Singh,et al.  Current zinc intake and risk of diabetes and coronary artery disease and factors associated with insulin resistance in rural and urban populations of North India. , 1998, Journal of the American College of Nutrition.

[44]  R. Palmiter,et al.  ZnT‐2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. , 1996, The EMBO journal.

[45]  R. Palmiter,et al.  Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. , 1994, Biochemistry.

[46]  A. Karginov,et al.  Sphingolipids Signaling in Lamellipodia Formation and Enhancement of Endothelial Barrier Function. , 2018, Current topics in membranes.

[47]  C. Drogemuller,et al.  Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation. , 2010, The review of diabetic studies : RDS.

[48]  Antonio Rosato,et al.  Counting the zinc-proteins encoded in the human genome. , 2006, Journal of proteome research.