Evidence for lysosomal processing of amyloid β-protein precursor in cultured cells

[1]  E. Masliah,et al.  An antiserum against amyloid β-protein precursor detects a unique peptide in Alzheimer brain , 1989, Neuroscience Letters.

[2]  Andreas Weidemann,et al.  Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein , 1989, Cell.

[3]  G. Cole,et al.  Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[4]  H. Wiśniewski,et al.  Immunoreactivity of neuronal lipofuscin with monoclonal antibodies to the amyloid β-protein , 1989, Neurobiology of Aging.

[5]  R. Katzman.,et al.  Decreased adhesiveness of alzheimer's disease fibroblasts: Is amyloid β‐protein precursor involved? , 1989, Annals of neurology.

[6]  M. Takeda,et al.  Lysosome instability in aged rat brain , 1989, Neuroscience Letters.

[7]  D. Maślińska,et al.  Immunoreactivity of ceroid lipofuscin storage pigment in Batten disease with monoclonal antibodies to the amyloid beta-protein. , 1989, The New England journal of medicine.

[8]  A. Ohlsson,et al.  Retinopathy of prematurity and bilirubin. , 1989, The New England journal of medicine.

[9]  G. Sarkis,et al.  Decline in protease activities with age in the nematode caenorhabditis elegans , 1988, Mechanisms of Ageing and Development.

[10]  R. Martins,et al.  A4 amyloid protein deposition and the diagnosis of Alzheimer's disease , 1988, Neurology.

[11]  D. Selkoe,et al.  Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[12]  G. Cole,et al.  Amyloid beta protein precursor is possibly a heparan sulfate proteoglycan core protein. , 1988, Science.

[13]  S. Love,et al.  Alz-50, Ubiquitin and Tau Immunoreactivity of Neurofibrillary Tangles, Pick Bodies and Lewy Bodies , 1988, Journal of neuropathology and experimental neurology.

[14]  G. Glenner Alzheimer's disease: Its proteins and genes , 1988, Cell.

[15]  S. Shiojiri,et al.  Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity , 1988, Nature.

[16]  B. Greenberg,et al.  A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors , 1988, Nature.

[17]  L. Villa-komaroff,et al.  Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease , 1988, Nature.

[18]  A. Matus,et al.  Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins. , 1987, Biochemistry.

[19]  H. Wiśniewski,et al.  Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[20]  P. S. St George-Hyslop,et al.  Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. , 1987, Science.

[21]  M. Lerman,et al.  Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. , 1987, Science.

[22]  K. Grzeschik,et al.  The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor , 1987, Nature.

[23]  E. Yamada,et al.  Effects of weakly basic amines on proteolytic processing and terminal glycosylation of secretory proteins in cultured rat hepatocytes. , 1986, The Biochemical journal.

[24]  L. Rome,et al.  Lysosomal degradation of glycoproteins and glycosaminoglycans. Efflux and recycling of sulphate and N-acetylhexosamines. , 1986, The Biochemical journal.

[25]  G. Lynch,et al.  Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain. , 1984, Science.

[26]  R. Terry,et al.  Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia , 1967, Acta Neuropathologica.

[27]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[28]  B. Greenberg,et al.  A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors , 1988 .

[29]  G. Cole,et al.  Aging-Related Pathology in Human Neuroblastoma and Teratocarcinoma Cell Lines , 1987 .