Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma
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L. Larue | I. Davidson | P. Laurette | G. Mengus | P. Sohier | G. Davidson | Sébastien Coassolo | Wen-Bo Yao | I. Michel | Giovanni Gambi | Mei Li
[1] K. Flaherty,et al. Toward Minimal Residual Disease-Directed Therapy in Melanoma , 2018, Cell.
[2] T. Graeber,et al. Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress. , 2018, Cancer cell.
[3] G. Berx,et al. Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes. , 2017, Cell stem cell.
[4] Hannah E Seberg,et al. Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma , 2017, Pigment cell & melanoma research.
[5] Janet Iwasa,et al. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes , 2017, Nature Reviews Molecular Cell Biology.
[6] E. Schadt,et al. Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation. , 2017, JCI insight.
[7] Jonathan M. Cairns,et al. Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation. , 2017, Molecular cell.
[8] D. Watkins-Chow,et al. BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation , 2017, Nucleic acids research.
[9] Satyaki Sengupta,et al. Super-Enhancer-Driven Transcriptional Dependencies in Cancer. , 2017, Trends in cancer.
[10] T. Braun,et al. TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo , 2017, PLoS genetics.
[11] G. Natoli,et al. In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype. , 2016, Cancer discovery.
[12] M. Bosenberg,et al. DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR. , 2016, Cell reports.
[13] J. Landsberg,et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment , 2015, Nature Communications.
[14] D. Gautheret,et al. New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis , 2015, Cell reports.
[15] A. McCallion,et al. Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes. , 2015, Human molecular genetics.
[16] L. Larue,et al. Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells , 2015, PLoS genetics.
[17] Steven J. M. Jones,et al. Genomic Classification of Cutaneous Melanoma , 2015, Cell.
[18] S. Aerts,et al. Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state , 2015, Nature Communications.
[19] S. Aerts,et al. Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells , 2015, eLife.
[20] C. Néri,et al. Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice. , 2015, Human molecular genetics.
[21] L. Soroceanu,et al. The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy , 2015, Journal of the National Cancer Institute.
[22] J. Lieb,et al. What are super-enhancers? , 2014, Nature Genetics.
[23] M. McMahon,et al. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma. , 2013, The Journal of clinical investigation.
[24] R. Young,et al. Super-Enhancers in the Control of Cell Identity and Disease , 2013, Cell.
[25] H. Kluger,et al. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of BrafV600E::Pten−/− melanoma , 2013, Oncogene.
[26] W. Pavan,et al. A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors , 2013, PLoS genetics.
[27] David A. Orlando,et al. Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes , 2013, Cell.
[28] J. Landsberg,et al. Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation , 2012, Nature.
[29] M. Wegner,et al. Chromatin-remodeling factor Brg1 is required for Schwann cell differentiation and myelination. , 2012, Developmental cell.
[30] D. Rimm,et al. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. , 2011, Cancer cell.
[31] F. Rambow,et al. General strategy to analyse melanoma in mice , 2011, Pigment cell & melanoma research.
[32] C. Bertolotto,et al. Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma , 2011, Oncogene.
[33] A. Singer,et al. Chromatin remodeling complex NURF regulates thymocyte maturation. , 2011, Genes & development.
[34] Tao Ye,et al. seqMINER: an integrated ChIP-seq data interpretation platform , 2010, Nucleic acids research.
[35] M. Martinka,et al. BRG1 expression is increased in human cutaneous melanoma , 2010, The British journal of dermatology.
[36] N. Dhomen,et al. Inducible expression of V600EBraf using tyrosinase‐driven Cre recombinase results in embryonic lethality , 2010, Pigment cell & melanoma research.
[37] H. Qi,et al. Heterogeneous SWI/SNF Chromatin Remodeling Complexes Promote Expression of Microphthalmia —Associated Transcription Factor Target Genes in Melanoma , 2009, Oncogene.
[38] J. Reis-Filho,et al. Oncogenic Braf induces melanocyte senescence and melanoma in mice. , 2009, Cancer cell.
[39] R. DePinho,et al. BRafV600E cooperates with Pten silencing to elicit metastatic melanoma , 2009, Nature Genetics.
[40] P. Nuciforo,et al. Brn-2 represses microphthalmia-associated transcription factor expression and marks a distinct subpopulation of microphthalmia-associated transcription factor-negative melanoma cells. , 2008, Cancer research.
[41] Clifford A. Meyer,et al. Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.
[42] Y. Ohkawa,et al. The Microphthalmia-associated Transcription Factor Requires SWI/SNF Enzymes to Activate Melanocyte-specific Genes* , 2006, Journal of Biological Chemistry.
[43] James A. Cuff,et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.
[44] L. Larue,et al. Spatiotemporal gene control by the Cre‐ERT2 system in melanocytes , 2006, Genesis.
[45] P. Chambon,et al. Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation , 2005, Development.
[46] T. Sasaki,et al. T cell-specific loss of Pten leads to defects in central and peripheral tolerance. , 2001, Immunity.