Contribution of In Vivo Structural Measurements and Load/Strength Ratios to the Determination of Forearm Fracture Risk in Postmenopausal Women

Bone structure, strength, and load‐strength ratios contribute to forearm fracture risk independently of areal BMD.

[1]  P. Rüegsegger,et al.  In vivo high resolution 3D-QCT of the human forearm. , 1998, Technology and health care : official journal of the European Society for Engineering and Medicine.

[2]  S. Bandinelli,et al.  Structural adaptations to bone loss in aging men and women. , 2006, Bone.

[3]  P. Rüegsegger,et al.  Ridge number density: a new parameter for in vivo bone structure analysis. , 1997, Bone.

[4]  L. Claes,et al.  Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[5]  Ralph Müller,et al.  Mechanical and Architectural Bone Adaptation in Early Stage Experimental Osteoarthritis , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[6]  J. Stepan,et al.  The Risk of Colles’ Fracture is Associated with the Collagen I Alpha1 Sp1 Polymorphism and Ultrasound Transmission Velocity in the Calcaneus Only in Heavier Postmenopausal Women , 2005, Calcified Tissue International.

[7]  S. Cummings,et al.  TYPE OF FALL AND RISK OF HIP AND WRIST FRACTURES: THE STUDY OF OSTEOPOROTIC FRACTURES , 1993, Journal of the American Geriatrics Society.

[8]  P. Guy,et al.  Accuracy of pQCT for evaluating the aged human radius: an ashing, histomorphometry and failure load investigation , 2006, Osteoporosis International.

[9]  O Johnell,et al.  Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. , 1996, BMJ.

[10]  O. Bärenholdt,et al.  Geometric properties of distal radius and pathogenesis of Colles fracture: a peripheral quantitative computed tomography study. , 2001, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.

[11]  S. Robinovitch,et al.  Prediction of upper extremity impact forces during falls on the outstretched hand. , 1998, Journal of biomechanics.

[12]  C. Reiners,et al.  Bone Quality Parameters of the Distal Radius as Assessed by pQCT in Normal and Fractured Women , 2001, Osteoporosis International.

[13]  F. Eckstein,et al.  Image-based micro-finite-element modeling for improved distal radius strength diagnosis: moving from bench to bedside. , 2004, Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry.

[14]  M. Järvinen,et al.  The Injury Mechanisms of Osteoporotic Upper Extremity Fractures Among Older Adults: A Controlled Study of 287 Consecutive Patients and Their 108 Controls , 2000, Osteoporosis International.

[15]  M. Härmä,et al.  Trabecular osteopenia in Colles' fracture. , 1986, Acta orthopaedica Scandinavica.

[16]  M. Bouxsein,et al.  Biomechanics of Age-Related Fractures , 2001 .

[17]  P. Rüegsegger,et al.  In vivo reproducibility of three‐dimensional structural properties of noninvasive bone biopsies using 3D‐pQCT , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  L. Klenerman,et al.  Decreased radial bone mass in Colles' fracture. , 1984, Acta orthopaedica Scandinavica.

[19]  M. Bouxsein,et al.  Predicting the failure load of the distal radius , 2003, Osteoporosis International.

[20]  A. M. Parfitt,et al.  Age-related structural changes in trabecular and cortical bone: Cellular mechanisms and biomechanical consequences , 2006, Calcified Tissue International.

[21]  W. O'Fallon,et al.  Secondary osteoporosis and the risk of distal forearm fractures in men and women. , 2002, Bone.

[22]  M. Bouxsein,et al.  In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. , 2005, The Journal of clinical endocrinology and metabolism.

[23]  Ann L Oberg,et al.  Effects of Sex and Age on Bone Microstructure at the Ultradistal Radius: A Population‐Based Noninvasive In Vivo Assessment , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[24]  F. Eckstein,et al.  Strength Prediction of the Distal Radius by Bone Densitometry—Evaluation Using Biomechanical Tests , 2004, Annals of Biomedical Engineering.

[25]  F. Eckstein,et al.  Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. , 2002, Bone.

[26]  P. Delmas,et al.  Alterations of Cortical and Trabecular Architecture Are Associated With Fractures in Postmenopausal Women, Partially Independent of Decreased BMD Measured by DXA: The OFELY Study , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  Wilson C. Hayes,et al.  Geometric variables from DXA of the radius predict forearm fracture load in vitro , 1993, Calcified Tissue International.

[28]  D. V. Griffiths,et al.  Programming the finite element method , 1982 .

[29]  Ralph Müller,et al.  Prediction of failure load using micro-finite element analysis models: Toward in vivo strength assessment. , 2006, Drug discovery today. Technologies.

[30]  P. C. Amadio,et al.  Long-Term Trends in the Incidence of Distal Forearm Fractures , 1998, Osteoporosis International.

[31]  A. Oberg,et al.  Population‐Based Analysis of the Relationship of Whole Bone Strength Indices and Fall‐Related Loads to Age‐ and Sex‐Specific Patterns of Hip and Wrist Fractures , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[32]  Ego Seeman,et al.  Bone Fragility: Failure of Periosteal Apposition to Compensate for Increased Endocortical Resorption in Postmenopausal Women , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[33]  M. R. Forwood,et al.  Mechanical Effects on the Skeleton: Are There Clinical Implications? , 2001, Osteoporosis International.

[34]  P J Prendergast,et al.  Finite element models in tissue mechanics and orthopaedic implant design. , 1997, Clinical biomechanics.

[35]  M. Drezner,et al.  Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee , 1987, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[36]  Failure of trabecular bone with simulated lytic defects can be predicted non‐invasively by structural analysis , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[37]  Mary L Bouxsein,et al.  Determinants of skeletal fragility. , 2005, Best practice & research. Clinical rheumatology.

[38]  P. Rüegsegger,et al.  Calibration of trabecular bone structure measurements of in vivo three-dimensional peripheral quantitative computed tomography with 28-microm-resolution microcomputed tomography. , 1999, Bone.

[39]  Liang Yu,et al.  Structure Analysis of the Was , 2002 .

[40]  B. Snyder,et al.  Noninvasive Imaging Predicts Failure Load of the Spine with Simulated Osteolytic Defects*† , 2000, The Journal of bone and joint surgery. American volume.

[41]  R. Eastell Forearm fracture. , 1996, Bone.

[42]  D. V. Griffiths,et al.  Programming the finite element method (2nd ed.) , 1988 .

[43]  D. Hamblen,et al.  Quantitative gamma-ray computed tomography of the radius in normal subjects and osteoporotic patients. , 1990, The British journal of radiology.

[44]  T M Keaveny,et al.  Biomechanical consequences of an isolated overload on the human vertebral body , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[45]  Sundeep Khosla,et al.  Population‐Based Study of Age and Sex Differences in Bone Volumetric Density, Size, Geometry, and Structure at Different Skeletal Sites , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[46]  D. I. Rowley,et al.  Prediction of Bone Strength from Cancellous Structure of the Distal Radius: Can We Improve on DXA? , 2000, Osteoporosis International.