A breakdown of metabolic reprogramming in microglia induced by CKLF1 exacerbates immune tolerance in ischemic stroke

[1]  C. Bushnell,et al.  Early peripheral blood gene expression associated with good and poor 90-day ischemic stroke outcomes , 2023, Journal of Neuroinflammation.

[2]  S. Shi,et al.  Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex , 2022, Nature Neuroscience.

[3]  Hao Li,et al.  Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study , 2022, Journal of Neuroinflammation.

[4]  Hongzhuan Chen,et al.  A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson’s disease , 2022, Journal of neuroinflammation.

[5]  Yong Tang,et al.  Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice , 2022, Journal of neuroinflammation.

[6]  Li-yuan Cui,et al.  Neuronal chemokine-like-factor 1 (CKLF1) up-regulation promotes M1 polarization of microglia in rat brain after stroke , 2021, Acta Pharmacologica Sinica.

[7]  Cynthia A. Reinhart-King,et al.  Mechanoresponsive metabolism in cancer cell migration and metastasis. , 2021, Cell metabolism.

[8]  A. Peters,et al.  Circulating interleukin-6 levels and incident ischemic stroke: a systematic review and meta-analysis of population-based cohort studies , 2021, medRxiv.

[9]  R. Dasheiff.  Reader Response: Association of Prestroke Metformin Use, Stroke Severity, and Thrombolysis Outcome , 2021, Neurology.

[10]  V. Dolinsky,et al.  BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation , 2020, Autophagy.

[11]  Zhi Chen,et al.  Chemokine-like factor 1: A promising therapeutic target in human diseases , 2020, Experimental biology and medicine.

[12]  Adrien E. D. Groot,et al.  Association of prestroke metformin use, stroke severity, and thrombolysis outcome , 2020, Neurology.

[13]  Charles T. Hindmarch,et al.  Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension , 2020, Circulation research.

[14]  K. Pennypacker,et al.  Expression of Cytokines and Chemokines as Predictors of Stroke Outcomes in Acute Ischemic Stroke , 2020, Frontiers in Neurology.

[15]  O. Butovsky,et al.  Microglia, Lifestyle Stress, and Neurodegeneration. , 2020, Immunity.

[16]  Steve Lianoglou,et al.  TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge , 2019, Neuron.

[17]  S. Duan,et al.  mTOR‐mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP , 2019, Glia.

[18]  Sung Hoon Baik,et al.  A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease. , 2019, Cell metabolism.

[19]  Ahsen Chaudhry,et al.  A pipeline for multidimensional confocal analysis of mitochondrial morphology, function and dynamics in pancreatic β-cells , 2019, bioRxiv.

[20]  Shi-feng Chu,et al.  CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4 , 2019, Cellular and Molecular Neurobiology.

[21]  Mohajeet B. Bhuckory,et al.  Glucose transporter 1 critically controls microglial activation through facilitating glycolysis , 2019, Molecular Neurodegeneration.

[22]  C. Justicia,et al.  Microglial cell loss after ischemic stroke favors brain neutrophil accumulation , 2018, Acta Neuropathologica.

[23]  Ping-Chih Ho,et al.  Determining Macrophage Polarization upon Metabolic Perturbation. , 2018, Methods in molecular biology.

[24]  H. Weiner,et al.  Microglial signatures and their role in health and disease , 2018, Nature Reviews Neuroscience.

[25]  A. Lerman,et al.  Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation. , 2018, Cell metabolism.

[26]  N. Chen,et al.  Progress in pharmacological research of chemokine like factor 1 (CKLF1) , 2018, Cytokine.

[27]  Andrew J. F. Valente,et al.  A simple ImageJ macro tool for analyzing mitochondrial network morphology in mammalian cell culture. , 2017, Acta histochemica.

[28]  R. Ransohoff.  A polarizing question: do M1 and M2 microglia exist? , 2016, Nature Neuroscience.

[29]  Maxim N. Artyomov,et al.  Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. , 2016, Cell metabolism.

[30]  P. Crino.  The mTOR signalling cascade: paving new roads to cure neurological disease , 2016, Nature Reviews Neurology.

[31]  S. Rivest,et al.  Microglia in Alzheimer’s disease: A multifaceted relationship , 2016, Brain, Behavior, and Immunity.

[32]  R. Xavier,et al.  Trained immunity: A program of innate immune memory in health and disease , 2016, Science.

[33]  Susan R. Quinn,et al.  Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages. , 2015, Cell metabolism.

[34]  R. Xavier,et al.  mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity , 2014, Science.

[35]  R. Xavier,et al.  Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity , 2014, Science.

[36]  M. O’Banion,et al.  Neuroinflammation and M2 microglia: the good, the bad, and the inflamed , 2014, Journal of Neuroinflammation.

[37]  S. Gordon,et al.  The M1 and M2 paradigm of macrophage activation: time for reassessment , 2014, F1000prime reports.

[38]  B. Faubert,et al.  Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis , 2013, Cell.

[39]  U. Hanisch.  Functional diversity of microglia – how heterogeneous are they to begin with? , 2013, Front. Cell. Neurosci..

[40]  Liang Zheng,et al.  Succinate is an inflammatory signal that induces IL-1β through HIF-1α , 2013, Nature.

[41]  N. Chen,et al.  Developmental expression of chemokine-like factor 1, a novel member of chemokines family, in postnatal rat cerebral cortex , 2012, Neuroscience Letters.

[42]  N. Chen,et al.  Expression of chemokine-like factor 1 after focal cerebral ischemia in the rat , 2011, Neuroscience Letters.

[43]  H. Kettenmann,et al.  Physiology of microglia. , 2011, Physiological reviews.

[44]  R. Ransohoff,et al.  The myeloid cells of the central nervous system parenchyma , 2010, Nature.

[45]  S. Biswas,et al.  Endotoxin tolerance: new mechanisms, molecules and clinical significance. , 2009, Trends in immunology.

[46]  H. Neumann,et al.  Microglial clearance function in health and disease , 2009, Neuroscience.

[47]  H. Neumann,et al.  Debris clearance by microglia: an essential link between degeneration and regeneration , 2008, Brain : a journal of neurology.

[48]  H. Kettenmann,et al.  Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.

[49]  L. Wang,et al.  Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. , 2001, The Biochemical journal.

[50]  Dan Li,et al.  Two C-terminal peptides of human CKLF1 interact with the chemokine receptor CCR4. , 2008, The international journal of biochemistry & cell biology.

[51]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..