Maternal experiences of childhood maltreatment moderate patterns of mother-infant cortisol regulation under stress.

The relation between maternal and infant cortisol responses has been a subject of intense research over the past decade. Relatedly, it has been hypothesized that maternal history of childhood maltreatment (MCM) impacts stress regulation across generations. The current study employed four statistical approaches to determine how MCM influences the cortisol responses of 150 mothers and their 4-month-old infants during the Still-Face Paradigm. Results indicated that MCM moderated cortisol patterns in several ways. First, lower MCM mothers and infants had strong positive associations between cortisol levels measured at the same time point, whereas higher MCM mothers and infants did not show an association. Second, infants of higher MCM mothers had cortisol levels that were moderately high and remained elevated over the procedure, whereas infants of lower MCM mothers had decreasing cortisol levels over time. Third, higher MCM mothers and infants showed increasingly divergent cortisol levels over time, compared to lower MCM dyads. Finally, patterns of cross-lagged influence of infant cortisol on subsequent maternal cortisol were moderated by MCM, such that lower MCM mothers were influenced by their infants' cortisol levels at earlier time points than higher MCM mothers. These findings highlight MCM as one contributor to processes of stress regulation in the mother-infant dyad.

[1]  L. Atkinson,et al.  Mother–infant cortisol attunement: Associations with mother–infant attachment disorganization , 2019, Development and Psychopathology.

[2]  Lenneke R. A. Alink,et al.  The effect of maltreatment experiences on maltreating and dysfunctional parenting: A search for mechanisms , 2019, Development and Psychopathology.

[3]  J. Pearson,et al.  Maternal history of childhood maltreatment and later parenting behavior: A meta-analysis , 2019, Development and Psychopathology.

[4]  Leah C. Hibel,et al.  Child Maltreatment and Mother–Child Transmission of Stress Physiology , 2019, Child maltreatment.

[5]  C. Pariante,et al.  When one childhood meets another – maternal childhood trauma and offspring child psychopathology: A systematic review , 2018, Clinical child psychology and psychiatry.

[6]  Martin Styner,et al.  Intergenerational Effect of Maternal Exposure to Childhood Maltreatment on Newborn Brain Anatomy , 2018, Biological Psychiatry.

[7]  Tessa V. West,et al.  Measuring Physiological Influence in Dyads: A Guide to Designing, Implementing, and Analyzing Dyadic Physiological Studies , 2017, Psychological methods.

[8]  Cassandra L. Hendrix,et al.  Physiological attunement in mother–infant dyads at clinical high risk: The influence of maternal depression and positive parenting , 2017, Development and Psychopathology.

[9]  M. Kaess,et al.  The effect of a maternal history of childhood abuse on adrenocortical attunement in mothers and their toddlers , 2017, Developmental psychobiology.

[10]  D. Fair,et al.  Intergenerational Transmission of Maternal Childhood Maltreatment Exposure: Implications for Fetal Brain Development. , 2017, Journal of the American Academy of Child and Adolescent Psychiatry.

[11]  D. Kashy,et al.  Do different data analytic approaches generate discrepant findings when measuring mother–infant HPA axis attunement? , 2017, Developmental psychobiology.

[12]  J. Khoury,et al.  Stress Physiology in Infancy and Early Childhood: Cortisol Flexibility, Attunement and Coordination , 2016, Journal of neuroendocrinology.

[13]  M. Kaess,et al.  Sex-specific differences in adrenocortical attunement in mothers with a history of childhood abuse and their 5-month-old boys and girls , 2016, Journal of Neural Transmission.

[14]  R. Mccall,et al.  The Genetic and Environmental Origins of Learning Abilities and Disabilities in the Early School , 2007, Monographs of the Society for Research in Child Development.

[15]  Cassandra L. Hendrix,et al.  Maternal early-life trauma and affective parenting style: the mediating role of HPA-axis function , 2016, Archives of Women's Mental Health.

[16]  Marissa Stroo,et al.  Correlation between maternal and infant cortisol varies by breastfeeding status. , 2015, Infant behavior & development.

[17]  Adela C. Timmons,et al.  Physiological linkage in couples and its implications for individual and interpersonal functioning: A literature review. , 2015, Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association.

[18]  Martin H. Teicher,et al.  The ‘Maltreatment and Abuse Chronology of Exposure’ (MACE) Scale for the Retrospective Assessment of Abuse and Neglect During Development , 2015, PloS one.

[19]  C. Blair,et al.  Maternal-child adrenocortical attunement in early childhood: continuity and change. , 2015, Developmental psychobiology.

[20]  H. Kim,et al.  Maternal abuse history and self-regulation difficulties in preadolescence. , 2014, Child abuse & neglect.

[21]  M. Beeghly,et al.  Maternal parenting predicts infant biobehavioral regulation among women with a history of childhood maltreatment , 2014, Development and Psychopathology.

[22]  R. Borgatti,et al.  Four-Month-Old Infants’ Long-Term Memory for a Stressful Social Event , 2013, PloS one.

[23]  D. Kashy,et al.  Maternal sensitivity and infant and mother adrenocortical function across challenges , 2013, Psychoneuroendocrinology.

[24]  B. Holmes,et al.  Maternal Disrupted Communication During Face-to-Face Interaction at 4 months: Relation to Maternal and Infant Cortisol Among at-Risk Families. , 2013, Infancy : the official journal of the International Society on Infant Studies.

[25]  M. Gunnar,et al.  Future Directions in the Study of Social Relationships as Regulators of the HPA Axis Across Development , 2013, Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53.

[26]  Sarah J. Erickson,et al.  Differential associations between infant affective and cortisol responses during the still face paradigm among infants born very low birth weight versus full-term. , 2013, Infant behavior & development.

[27]  R. Feldman.  Bio-behavioral Synchrony: A Model for Integrating Biological and Microsocial Behavioral Processes in the Study of Parenting , 2012 .

[28]  Laura L. Nathans,et al.  Asynchrony of mother-infant hypothalamic-pituitary-adrenal axis activity following extinction of infant crying responses induced during the transition to sleep. , 2012, Early human development.

[29]  Rebecca L. Stelter,et al.  Parent emotional expressiveness and children's self-regulation: associations with abused children's school functioning. , 2012, Child abuse & neglect.

[30]  Heidemarie K. Laurent,et al.  Taking stress response out of the box: stability, discontinuity, and temperament effects on HPA and SNS across social stressors in mother-infant dyads. , 2012, Developmental psychology.

[31]  Heidemarie K. Laurent,et al.  Risky shifts: How the timing and course of mothers' depressive symptoms across the perinatal period shape their own and infant's stress response profiles , 2011, Development and Psychopathology.

[32]  P. Brennan,et al.  The impact of maternal childhood abuse on maternal and infant HPA axis function in the postpartum period , 2010, Psychoneuroendocrinology.

[33]  Ruth Feldman,et al.  Touch attenuates infants' physiological reactivity to stress. , 2010, Developmental science.

[34]  C. McMahon,et al.  Maternal prenatal anxiety, postnatal caregiving and infants' cortisol responses to the still-face procedure. , 2009, Developmental psychobiology.

[35]  M. Cox,et al.  Intimate partner violence moderates the association between mother-infant adrenocortical activity across an emotional challenge. , 2009, Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association.

[36]  Judi Mesman,et al.  The many faces of the Still-Face Paradigm: A review and meta-analysis , 2009 .

[37]  D. Cicchetti,et al.  The past achievements and future promises of developmental psychopathology: the coming of age of a discipline. , 2009, Journal of child psychology and psychiatry, and allied disciplines.

[38]  J. Riksen-Walraven,et al.  Adrenocortical and behavioral attunement in parents with 1-year-old infants. , 2008, Developmental psychobiology.

[39]  L. Thompson,et al.  Cortisol reactivity, maternal sensitivity, and learning in 3-month-old infants. , 2008, Infant behavior & development.

[40]  Caroline E. Wright,et al.  Poor sleep the night before an experimental stress task is associated with reduced cortisol reactivity in healthy women , 2007, Biological Psychology.

[41]  M. Lewis,et al.  Infant emotional and cortisol responses to goal blockage. , 2005, Child development.

[42]  S. Dickerson,et al.  Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research. , 2004, Psychological bulletin.

[43]  David W. Haley,et al.  Infant stress and parent responsiveness: regulation of physiology and behavior during still-face and reunion. , 2003, Child development.

[44]  K. Stansbury,et al.  Attunement of maternal and child adrenocortical response to child challenge , 2002, Psychoneuroendocrinology.

[45]  M. Gunnar,et al.  Social regulation of the cortisol levels in early human development , 2002, Psychoneuroendocrinology.

[46]  James D. A. Parker,et al.  The handbook of emotional intelligence : theory, development, assessment, and application at home, school, and in the workplace , 2000 .

[47]  A. Fleming,et al.  Neurobiology of mother–infant interactions: experience and central nervous system plasticity across development and generations , 1999, Neuroscience & Biobehavioral Reviews.

[48]  D. Williamson,et al.  Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. , 1998, American journal of preventive medicine.

[49]  J. Cassidy.  Emotion regulation: influences of attachment relationships. , 1994, Monographs of the Society for Research in Child Development.

[50]  C. Kopp.  Regulation of distress and negative emotions: A developmental view. , 1989 .

[51]  T. Brazelton,et al.  The infant's response to entrapment between contradictory messages in face-to-face interaction. , 1978, Journal of the American Academy of Child Psychiatry.