The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair

[1]  Le-Xin Wang,et al.  rBMSC/Cav-1F92A Mediates Oxidative Stress in PAH Rat by Regulating SelW/14-3-3η and CA1/Kininogen Signal Transduction , 2019, Stem cells international.

[2]  S. Xiao,et al.  Schwann Cell-Like Cells Derived from Human Amniotic Mesenchymal Stem Cells Promote Peripheral Nerve Regeneration through a MicroRNA-214/c-Jun Pathway , 2019, Stem cells international.

[3]  P. Tos,et al.  The Median Nerve Injury Model in Pre-clinical Research – A Critical Review on Benefits and Limitations , 2019, Front. Cell. Neurosci..

[4]  J. Heinzel,et al.  Spatiotemporal Differences in Gene Expression Between Motor and Sensory Autografts and Their Effect on Femoral Nerve Regeneration in the Rat , 2019, Front. Cell. Neurosci..

[5]  Sung-Rae Cho,et al.  Optogenetic stimulation promotes Schwann cell proliferation, differentiation, and myelination in vitro , 2019, Scientific Reports.

[6]  M. Wiberg,et al.  Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer , 2018, Stem Cell Research & Therapy.

[7]  C. Schuh,et al.  An Optimized Collagen-Fibrin Blend Engineered Neural Tissue Promotes Peripheral Nerve Repair , 2018, Tissue engineering. Part A.

[8]  Jiang Peng,et al.  Applications of stem cell-derived exosomes in tissue engineering and neurological diseases , 2018, Reviews in the neurosciences.

[9]  H. Okano,et al.  Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration , 2018, Scientific Reports.

[10]  A. Tripathi,et al.  Schwann cell durotaxis can be guided by physiologically relevant stiffness gradients , 2018, Biomaterials Research.

[11]  E. Couve,et al.  Schwann Cell Phenotype Changes in Aging Human Dental Pulp , 2018, Journal of dental research.

[12]  J. Haycock,et al.  Pre-clinical evaluation of advanced nerve guide conduits using a novel 3D in vitro testing model , 2017, International journal of bioprinting.

[13]  Yang Wang,et al.  The effect of co-transplantation of nerve fibroblasts and Schwann cells on peripheral nerve repair , 2017, International journal of biological sciences.

[14]  A. Lloyd,et al.  Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve , 2017, Development.

[15]  Jessica K. Alexander,et al.  Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs , 2017, eNeuro.

[16]  Jie Liu,et al.  Validating myelin water imaging with transmission electron microscopy in a rat spinal cord injury model , 2017, NeuroImage.

[17]  J. A. Stratton,et al.  Purification and Characterization of Schwann Cells from Adult Human Skin and Nerve , 2017, eNeuro.

[18]  Rebecca J Shipley,et al.  An integrated theoretical‐experimental approach to accelerate translational tissue engineering , 2017, Journal of tissue engineering and regenerative medicine.

[19]  M. Cecchini,et al.  Neuregulin 1 functionalization of organic fibers for Schwann cell guidance , 2017, Nanotechnology.

[20]  E. Raharjo,et al.  Improved method to track and precisely count Schwann cells post-transplantation in a peripheral nerve injury model , 2016, Journal of Neuroscience Methods.

[21]  Peng Luo,et al.  Tissue-engineered rhesus monkey nerve grafts for the repair of long ulnar nerve defects: similar outcomes to autologous nerve grafts , 2016, Neural regeneration research.

[22]  M. Wegner,et al.  Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination , 2016, Brain Research.

[23]  C. Schuh,et al.  Extracorporeal shockwave treatment: A novel tool to improve Schwann cell isolation and culture. , 2016, Cytotherapy.

[24]  P. Ma,et al.  Electroactive biodegradable polyurethane significantly enhanced Schwann cells myelin gene expression and neurotrophin secretion for peripheral nerve tissue engineering. , 2016, Biomaterials.

[25]  A. Daugherty,et al.  TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions , 2016, PloS one.

[26]  C. Schuurmans,et al.  Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve , 2016, PloS one.

[27]  E. Raharjo,et al.  Adult skin-derived precursor Schwann cells exhibit superior myelination and regeneration supportive properties compared to chronically denervated nerve-derived Schwann cells , 2016, Experimental Neurology.

[28]  R. Mirsky,et al.  The repair Schwann cell and its function in regenerating nerves , 2016, The Journal of physiology.

[29]  Eun-Mi Hur,et al.  Coculture of Primary Motor Neurons and Schwann Cells as a Model for In Vitro Myelination , 2015, Scientific Reports.

[30]  Prakhar Mishra,et al.  The overwhelming use of rat models in nerve regeneration research may compromise designs of nerve guidance conduits for humans , 2015, Journal of Materials Science: Materials in Medicine.

[31]  Valeria Chiono,et al.  Trends in the design of nerve guidance channels in peripheral nerve tissue engineering , 2015, Progress in Neurobiology.

[32]  C. Schmidt,et al.  Amine-functionalized polypyrrole: Inherently cell adhesive conducting polymer. , 2015, Journal of biomedical materials research. Part A.

[33]  M. Dezawa,et al.  Mesenchymal Stem Cells as a Source of Schwann Cells: Their Anticipated Use in Peripheral Nerve Regeneration , 2015, Cells Tissues Organs.

[34]  C. Tonda-Turo,et al.  A Combination of Schwann-Cell Grafts and Aerobic Exercise Enhances Sciatic Nerve Regeneration , 2014, PloS one.

[35]  C. V. van Blitterswijk,et al.  Peptide functionalized polyhydroxyalkanoate nanofibrous scaffolds enhance Schwann cells activity. , 2014, Nanomedicine : nanotechnology, biology, and medicine.

[36]  J. Haycock,et al.  Amine functionalized nanodiamond promotes cellular adhesion, proliferation and neurite outgrowth , 2014, Biomedical materials.

[37]  Christine M. Miller,et al.  Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration , 2014, Neuron.

[38]  D. Attwell,et al.  The node of Ranvier in CNS pathology , 2014, Acta Neuropathologica.

[39]  Kunzheng Wang,et al.  Schwann-like cells seeded in acellular nerve grafts improve nerve regeneration , 2014, BMC Musculoskeletal Disorders.

[40]  Younan Xia,et al.  Nerve Guidance Conduits Based on Double-Layered Scaffolds of Electrospun Nanofibers for Repairing the Peripheral Nervous System , 2014, ACS applied materials & interfaces.

[41]  E. Biazar,et al.  Rat Sciatic Nerve Reconstruction Across a 30 mm Defect Bridged by an Oriented Porous PHBV Tube With Schwann Cell as Artificial Nerve Graft , 2014, ASAIO journal.

[42]  Gabor Forgacs,et al.  Biofabrication and testing of a fully cellular nerve graft , 2013, Biofabrication.

[43]  F. Court,et al.  Schwann cell‐derived exosomes enhance axonal regeneration in the peripheral nervous system , 2013, Glia.

[44]  M. Schachner,et al.  Gold nanoparticles functionalized with a fragment of the neural cell adhesion molecule L1 stimulate L1-mediated functions. , 2013, Nanoscale.

[45]  H. Davies,et al.  Engineered neural tissue for peripheral nerve repair. , 2013, Biomaterials.

[46]  D. Kalyon,et al.  Laminin Functionalized Biomimetic Nanofibers For Nerve Tissue Engineering. , 2013, Journal of biomaterials and tissue engineering.

[47]  J. Elfar,et al.  Nerve physiology: mechanisms of injury and recovery. , 2013, Hand clinics.

[48]  M. M. Pradas,et al.  Polymer chains incorporating caprolactone and arginine–glycine–aspartic acid functionalities: Synthesis, characterization and biological response in vitro of the Schwann cell , 2013 .

[49]  M. Yaszemski,et al.  A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds. , 2012, Biomaterials.

[50]  J. Haycock,et al.  Integrated culture and purification of rat Schwann cells from freshly isolated adult tissue , 2012, Nature Protocols.

[51]  Yumin Yang,et al.  The influence of substrate stiffness on the behavior and functions of Schwann cells in culture. , 2012, Biomaterials.

[52]  John W Haycock,et al.  An aligned 3D neuronal-glial co-culture model for peripheral nerve studies. , 2012, Biomaterials.

[53]  R. Mirsky,et al.  Regulation of Schwann cell differentiation and proliferation by the Pax‐3 transcription factor , 2012, Glia.

[54]  B N Chichkov,et al.  Two-photon polymerization-generated and micromolding-replicated 3D scaffolds for peripheral neural tissue engineering applications , 2012, Biofabrication.

[55]  Jiang Peng,et al.  Recellularized nerve allografts with differentiated mesenchymal stem cells promote peripheral nerve regeneration , 2012, Neuroscience Letters.

[56]  A. Höke,et al.  Human Neural Crest Stem Cells Derived from Human ESCs and Induced Pluripotent Stem Cells: Induction, Maintenance, and Differentiation into Functional Schwann Cells , 2012, Stem cells translational medicine.

[57]  John W Haycock,et al.  Next generation nerve guides: materials, fabrication, growth factors, and cell delivery. , 2012, Tissue engineering. Part B, Reviews.

[58]  S. Mackinnon,et al.  Differential gene expression in motor and sensory Schwann cells in the rat femoral nerve , 2012, Journal of neuroscience research.

[59]  W. Lineaweaver,et al.  Comparisons of outcomes from repair of median nerve and ulnar nerve defect with nerve graft and tubulization: a meta-analysis. , 2011, Journal of reconstructive microsurgery.

[60]  M. Wegner,et al.  Sox10 is required for Schwann‐cell homeostasis and myelin maintenance in the adult peripheral nerve , 2011, Glia.

[61]  S. Böhm,et al.  Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC , 2011, Cell Communication and Signaling.

[62]  J. Haycock,et al.  Anatomical site influences the differentiation of adipose‐derived stem cells for Schwann‐cell phenotype and function , 2011, Glia.

[63]  Jui-Sheng Sun,et al.  Effects of low intensity pulsed ultrasound on rat Schwann cells metabolism. , 2011, Artificial organs.

[64]  J. Svaren,et al.  Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination , 2010, Nature Neuroscience.

[65]  Xu Jiang,et al.  Current applications and future perspectives of artificial nerve conduits , 2010, Experimental Neurology.

[66]  F. Guillemot,et al.  Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity , 2009, Nature Neuroscience.

[67]  Fu Xiong,et al.  Myelin-forming ability of Schwann cell-like cells induced from rat adipose-derived stem cells in vitro , 2008, Brain Research.

[68]  D. Carey,et al.  Regulation of Schwann cell function by the extracellular matrix , 2008, Glia.

[69]  Rhona Mirsky,et al.  Negative regulation of myelination: Relevance for development, injury, and demyelinating disease , 2008, Glia.

[70]  Wutian Wu,et al.  Motor nerve graft is better than sensory nerve graft for survival and regeneration of motoneurons after spinal root avulsion in adult rats , 2008, Experimental Neurology.

[71]  S. Mackinnon,et al.  The impact of motor and sensory nerve architecture on nerve regeneration , 2008, Experimental Neurology.

[72]  A. Lloyd,et al.  c-Jun is a negative regulator of myelination , 2008, The Journal of cell biology.

[73]  J. Goh,et al.  Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. , 2008, Biomaterials.

[74]  H. Seçer,et al.  The clinical, electrophysiologic, and surgical characteristics of peripheral nerve injuries caused by gunshot wounds in adults: a 40-year experience. , 2008, Surgical neurology.

[75]  W. Tourtellotte,et al.  Regulation of low affinity neurotrophin receptor (p75NTR) by early growth response (Egr) transcriptional regulators , 2007, Molecular and Cellular Neuroscience.

[76]  Giselle Chamberlain,et al.  Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing , 2007, Stem cells.

[77]  R. Schmidt,et al.  Misexpression of Pou3f1 Results in Peripheral Nerve Hypomyelination and Axonal Loss , 2007, The Journal of Neuroscience.

[78]  M. Simons,et al.  Wrapping it up: the cell biology of myelination , 2007, Current Opinion in Neurobiology.

[79]  M. Nissinen,et al.  Isolation, purification and expansion of myelination‐competent, neonatal mouse Schwann cells , 2007, The European journal of neuroscience.

[80]  R. Redett,et al.  Schwann Cells Express Motor and Sensory Phenotypes That Regulate Axon Regeneration , 2006, The Journal of Neuroscience.

[81]  S. Hsu,et al.  Oriented Schwann cell growth on microgrooved surfaces , 2005, Biotechnology and bioengineering.

[82]  Jeffrey A. Loeb,et al.  Neuregulin-1 Type III Determines the Ensheathment Fate of Axons , 2005, Neuron.

[83]  R. Mirsky,et al.  The origin and development of glial cells in peripheral nerves , 2005, Nature Reviews Neuroscience.

[84]  M. Hedrick,et al.  Multipotential differentiation of adipose tissue-derived stem cells. , 2005, The Keio journal of medicine.

[85]  R. Schmidt,et al.  Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[86]  C. Schmidt,et al.  Optimized acellular nerve graft is immunologically tolerated and supports regeneration. , 2004, Tissue engineering.

[87]  M. Wiberg,et al.  Green fluorescent protein is a stable morphological marker for schwann cell transplants in bioengineered nerve conduits. , 2004, Tissue engineering.

[88]  Xiaosong Gu,et al.  The interaction of Schwann cells with chitosan membranes and fibers in vitro. , 2004, Biomaterials.

[89]  A. Flake,et al.  Mesenchymal stem cells: paradoxes of passaging. , 2004, Experimental hematology.

[90]  F. Barry,et al.  Mesenchymal stem cells: clinical applications and biological characterization. , 2004, The international journal of biochemistry & cell biology.

[91]  Elior Peles,et al.  The local differentiation of myelinated axons at nodes of Ranvier , 2003, Nature Reviews Neuroscience.

[92]  F. Doetsch,et al.  The glial identity of neural stem cells , 2003, Nature Neuroscience.

[93]  C. Real,et al.  Reversal of developmental restrictions in neural crest lineages: Transition from Schwann cells to glial-melanocytic precursors in vitro , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[94]  R. Mirsky,et al.  Signals that determine Schwann cell identity * , 2002, Journal of anatomy.

[95]  Guido Stoll,et al.  Degeneration and regeneration of the peripheral nervous system: From Augustus Waller's observations to neuroinflammation , 2002, Journal of the peripheral nervous system : JPNS.

[96]  Masahiko Takano,et al.  Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone‐marrow stromal cells , 2001, The European journal of neuroscience.

[97]  J. Vacanti,et al.  A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration. , 2000, Tissue engineering.

[98]  R. Tranquillo,et al.  Guided Neurite Elongation and Schwann Cell Invasion into Magnetically Aligned Collagen in Simulated Peripheral Nerve Regeneration , 1999, Experimental Neurology.

[99]  R. Mirsky,et al.  Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB , 1999, The Journal of Neuroscience.

[100]  D. Riethmacher,et al.  Severe neuropathies in mice with targeted mutations in the ErbB3 receptor , 1997, Nature.

[101]  M. Schachner,et al.  Molecular bases of myelin formation as revealed by investigations on mice deficient in glial cell surface molecules , 1997, Glia.

[102]  A. Blanchard,et al.  Oct‐6 (SCIP Tst‐1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: Comparison with Oct‐1, Krox‐20, and Pax‐3 , 1996, Journal of neuroscience research.

[103]  C. Idé Peripheral nerve regeneration , 1996, Neuroscience Research.

[104]  G. Lundborg,et al.  Pre-degenerated nerve grafts enhance regeneration by shortening the initial delay period , 1994, Brain Research.

[105]  G. Ciment,et al.  Basic fibroblast growth factor (bFGF) acts intracellularly to cause the transdifferentiation of avian neural crest-derived Schwann cell precursors into melanocytes. , 1993, Development.

[106]  G. Lundborg,et al.  The Influence of Predegeneration on Regeneration through Peripheral Nerve Grafts in the Rat , 1993, Experimental Neurology.

[107]  M. E. Eichler,et al.  The influence of fibronectin and laminin during Schwann cell migration and peripheral nerve regeneration through silicon chambers , 1993, Journal of neurocytology.

[108]  H. Thoenen,et al.  Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA , 1992, The Journal of cell biology.

[109]  P Aebischer,et al.  Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[110]  M. Schachner,et al.  Inhibition of Schwann cell myelination in vitro by antibody to the L1 adhesion molecule , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[111]  R. Bunge,et al.  Differentiation of Axon-related Schwann Cells in Vitro. I. Ascorbic Acid Regulates Basal Lamina Assembly and Myelin Formation , 1989 .

[112]  M. Schwab,et al.  Cellular localization of nerve growth factor synthesis by in situ hybridization. , 1987, The EMBO journal.

[113]  M. Moscarello,et al.  Identification of membrane-embedded domains of lipophilin from human myelin. , 1985, Biochemistry.

[114]  R. Bunge,et al.  Factors influencing the release of proteins by cultured schwann cells , 1981, The Journal of cell biology.

[115]  M H Ellisman,et al.  Development of axonal membrane specializations defines nodes of Ranvier and precedes Schwann cell myelin elaboration. , 1980, Developmental biology.

[116]  P. Wood Separation of functional Schwann cells and neurons from normal peripheral nerve tissue , 1976, Brain Research.

[117]  H. Cravioto The role of Schwann cells in the development of human peripheral nerves. An electron microscopic study. , 1965, Journal of ultrastructure research.

[118]  P. Masson Experimental and Spontaneous Schwannomas (Peripheral Gliomas): II. Spontaneous Schwannomas. , 1932, The American journal of pathology.

[119]  C. Taveggia,et al.  DRG Neuron/Schwann Cells Myelinating Cocultures. , 2018, Methods in molecular biology.

[120]  D. Kaplan,et al.  3D multi-channel bi-functionalized silk electrospun conduits for peripheral nerve regeneration. , 2015, Journal of the mechanical behavior of biomedical materials.

[121]  S. Soker,et al.  Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells. , 2013, Journal of the mechanical behavior of biomedical materials.

[122]  M. Schachner,et al.  Neural cell type-specific responses to glycomimetic functionalized collagen. , 2012, Biomaterials.

[123]  John W Haycock,et al.  Three-dimensional alignment of schwann cells using hydrolysable microfiber scaffolds: strategies for peripheral nerve repair. , 2011, Methods in molecular biology.

[124]  Y. Chan,et al.  The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells. , 2011, Biomaterials.

[125]  K. Haastert,et al.  Human and rat adult Schwann cell cultures: fast and efficient enrichment and highly effective non-viral transfection protocol , 2007, Nature Protocols.

[126]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.

[127]  Jeffrey Field,et al.  Schwann cells: origins and role in axonal maintenance and regeneration. , 2006, The international journal of biochemistry & cell biology.

[128]  H. Väänänen Mesenchymal stem cells. , 2005, Annals of medicine.

[129]  K. Nave,et al.  The transcription factor Sox10 is a key regulator of peripheral glial development. , 2001, Genes & development.

[130]  R. Brown,et al.  Adhesion, alignment, and migration of cultured Schwann cells on ultrathin fibronectin fibres. , 1999, Cell motility and the cytoskeleton.

[131]  S. Frostick,et al.  Schwann cells, neurotrophic factors, and peripheral nerve regeneration , 1998, Microsurgery.

[132]  J. M. Hopkins,et al.  In vitro myelination of regenerating adult rat retinal ganglion cell axons by schwann cells , 1991, Glia.

[133]  M. Bunge,et al.  Linkage between axonal ensheathment and basal lamina production by Schwann cells. , 1986, Annual review of neuroscience.

[134]  R. Stämpfli Saltatory conduction in nerve. , 1954 .