Linking lipids to Alzheimer's disease: cholesterol and beyond

[1]  Thomas W. Mühleisen,et al.  Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease , 2013, Nature Genetics.

[2]  M. Péter,et al.  Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms* , 2011, The Journal of Biological Chemistry.

[3]  C. Duyckaerts,et al.  Local cholesterol increase triggers amyloid precursor protein‐Bacel clustering in lipid rafts and rapid endocytosis , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  Ashley I. Bush,et al.  Therapeutics for Alzheimer’s disease based on the metal hypothesis , 2008, Neurotherapeutics.

[5]  S. Small,et al.  The phospholipase D1 pathway modulates macroautophagy. , 2010, Nature communications.

[6]  Matthew P. Frosch,et al.  The ACAT Inhibitor CP-113,818 Markedly Reduces Amyloid Pathology in a Mouse Model of Alzheimer's Disease , 2010, Neuron.

[7]  O. Arancio,et al.  Phospholipase D2 Ablation Ameliorates Alzheimer's Disease-Linked Synaptic Dysfunction and Cognitive Deficits , 2010, The Journal of Neuroscience.

[8]  D. Rubinsztein,et al.  Autophagy, a guardian against neurodegeneration , 2010, Seminars in cell & developmental biology.

[9]  D. Kovacs,et al.  ACAT inhibition and amyloid beta reduction. , 2010, Biochimica et biophysica acta.

[10]  P. Foley Lipids in Alzheimer's disease: A century-old story. , 2010, Biochimica et biophysica acta.

[11]  G. Eckert,et al.  Isoprenoids, small GTPases and Alzheimer's disease. , 2010, Biochimica et biophysica acta.

[12]  L. Mucke,et al.  Phospholipase A2 and arachidonic acid in Alzheimer's disease. , 2010, Biochimica et biophysica acta.

[13]  Koichi Kato,et al.  Abeta polymerization through interaction with membrane gangliosides. , 2010, Biochimica et biophysica acta.

[14]  Gopal Thinakaran,et al.  Membrane rafts in Alzheimer's disease beta-amyloid production. , 2010, Biochimica et biophysica acta.

[15]  T. Hartmann,et al.  Role of amyloid beta in lipid homeostasis. , 2010, Biochimica et biophysica acta.

[16]  Xianlin Han,et al.  Apolipoprotein E mediates sulfatide depletion in animal models of Alzheimer's disease , 2010, Neurobiology of Aging.

[17]  L. Mucke,et al.  Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks , 2010, Nature Neuroscience.

[18]  N. Bazan,et al.  Omega-3 Essential Fatty Acids Modulate Initiation and Progression of Neurodegenerative Disease , 2010, Molecular Neurobiology.

[19]  S. Sipione,et al.  Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction , 2010, FEBS letters.

[20]  L. Tsai,et al.  Negative regulation of Vps34 by Cdk mediated phosphorylation. , 2010, Molecular cell.

[21]  Tiago Gil Oliveira,et al.  Phospholipase D in brain function and Alzheimer's disease. , 2010, Biochimica et biophysica acta.

[22]  B. Hyman,et al.  Caspase activation precedes and leads to tangles , 2010, Nature.

[23]  Y. Zhong,et al.  PI3 kinase signaling is involved in Aβ-induced memory loss in Drosophila , 2010, Proceedings of the National Academy of Sciences.

[24]  D. Sparks,et al.  Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease , 2010, Neurology.

[25]  C. Gong,et al.  Deregulation of sphingolipid metabolism in Alzheimer's disease , 2010, Neurobiology of Aging.

[26]  M. Diamond,et al.  Prion-like mechanisms in neurodegenerative diseases , 2010, Nature Reviews Neuroscience.

[27]  N. Seidah,et al.  ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD , 2010, Proceedings of the National Academy of Sciences.

[28]  Amy E. Sanders,et al.  Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia. , 2010, JAMA.

[29]  Kai Simons,et al.  Lipid Rafts As a Membrane-Organizing Principle , 2010, Science.

[30]  J. Buxbaum,et al.  Profiling brain and plasma lipids in human APOE epsilon2, epsilon3, and epsilon4 knock-in mice using electrospray ionization mass spectrometry. , 2010, Journal of Alzheimer's disease : JAD.

[31]  D. Butterfield,et al.  In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. , 2010, Free radical biology & medicine.

[32]  David S. Park,et al.  Amyloid-β42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism , 2009, Proceedings of the National Academy of Sciences.

[33]  Y. Matsuoka,et al.  Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice , 2009, Neurobiology of Aging.

[34]  R. Kraut,et al.  Alternate raft pathways cooperate to mediate slow diffusion and efficient uptake of a sphingolipid tracer to degradative and recycling compartments , 2009, Journal of Cell Science.

[35]  Lars Bertram,et al.  Genome-wide association studies in Alzheimer's disease. , 2009, Human molecular genetics.

[36]  L. Kiemeney,et al.  Corrigendum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.

[37]  D. Lingwood,et al.  Lipid rafts as functional heterogeneity in cell membranes. , 2009, Biochemical Society transactions.

[38]  Joachim Herz,et al.  Reelin signaling antagonizes β-amyloid at the synapse , 2009, Proceedings of the National Academy of Sciences.

[39]  S. DeKosky,et al.  Simvastatin therapy prevents brain trauma‐induced increases in β‐amyloid peptide levels , 2009, Annals of neurology.

[40]  P. Bosco,et al.  Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease , 2009, Nature Genetics.

[41]  H. Feldman,et al.  Therapeutic potential of statins in Alzheimer's disease , 2009, Journal of the Neurological Sciences.

[42]  G. Cole,et al.  Omega-3 fatty acids and dementia. , 2009, Prostaglandins, leukotrienes, and essential fatty acids.

[43]  D. Volmer,et al.  Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients , 2009, Neurobiology of Disease.

[44]  D. Holtzman,et al.  The Role of Apolipoprotein E in Alzheimer's Disease , 2009, Neuron.

[45]  F. Maxfield,et al.  Intracellular sterol dynamics. , 2009, Biochimica et biophysica acta.

[46]  Liana C. Silva,et al.  Cholesterol-rich Fluid Membranes Solubilize Ceramide Domains , 2009, The Journal of Biological Chemistry.

[47]  Huaxi Xu,et al.  Intracellular Trafficking of Presenilin 1 Is Regulated by β-Amyloid Precursor Protein and Phospholipase D1* , 2009, Journal of Biological Chemistry.

[48]  Guojun Bu,et al.  Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy , 2009, Nature Reviews Neuroscience.

[49]  A. Salminen,et al.  Siglec receptors and hiding plaques in Alzheimer's disease , 2009, Journal of Molecular Medicine.

[50]  Adriana B Ferreira,et al.  Increased Membrane Cholesterol Might Render Mature Hippocampal Neurons More Susceptible to β-Amyloid-Induced Calpain Activation and Tau Toxicity , 2009, The Journal of Neuroscience.

[51]  H. Okkenhaug,et al.  Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels , 2009, The Journal of cell biology.

[52]  P. Wong,et al.  Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts* , 2009, Journal of Biological Chemistry.

[53]  Nick C Fox,et al.  Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease , 2009 .

[54]  R. Maccioni,et al.  Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): involvement of lipid rafts. , 2009, Journal of Alzheimer's disease : JAD.

[55]  C. Wellington,et al.  Why lipids are important for Alzheimer disease? , 2009, Molecular and Cellular Biochemistry.

[56]  A. Palmeri,et al.  Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus , 2008, The Journal of Neuroscience.

[57]  A. Arshad,et al.  STATINS, INCIDENT ALZHEIMER DISEASE, CHANGE IN COGNITIVE FUNCTION, AND NEUROPATHOLOGY , 2008, Neurology.

[58]  Scott A. Small,et al.  Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis , 2008, Neuron.

[59]  P. De Camilli,et al.  Regulation of postsynaptic AMPA responses by synaptojanin 1 , 2008, Proceedings of the National Academy of Sciences.

[60]  L. Mucke,et al.  Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease , 2008, Nature Neuroscience.

[61]  R. Tanzi,et al.  Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses , 2008, Nature Reviews Neuroscience.

[62]  D. Selkoe,et al.  Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment* , 2008, Journal of Biological Chemistry.

[63]  Kim N. Green,et al.  Linking Calcium to Aβ and Alzheimer's Disease , 2008, Neuron.

[64]  Y. Ihara,et al.  Phosphoinositides Suppress γ-Secretase in Both the Detergent-soluble and -insoluble States* , 2008, Journal of Biological Chemistry.

[65]  P. De Camilli,et al.  Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome , 2008, Proceedings of the National Academy of Sciences.

[66]  A. Brash,et al.  Routes to 4-Hydroxynonenal: Fundamental Issues in the Mechanisms of Lipid Peroxidation* , 2008, Journal of Biological Chemistry.

[67]  M. P. McDonald,et al.  Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review. , 2008, Journal of lipid research.

[68]  C. Collinet,et al.  The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development , 2008, Cell.

[69]  D. Berman,et al.  Oligomeric amyloid-β peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism , 2008, Nature Neuroscience.

[70]  S. Hell,et al.  Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons , 2008, The Journal of Neuroscience.

[71]  A. Tall,et al.  Cholesterol efflux pathways and other potential mechanisms involved in the athero‐protective effect of high density lipoproteins , 2008, Journal of internal medicine.

[72]  Yusuf A. Hannun,et al.  Principles of bioactive lipid signalling: lessons from sphingolipids , 2008, Nature Reviews Molecular Cell Biology.

[73]  G. Meer,et al.  Membrane lipids: where they are and how they behave , 2008, Nature Reviews Molecular Cell Biology.

[74]  T. Hartmann,et al.  Alzheimer’s disease: the lipid connection , 2007, Journal of neurochemistry.

[75]  Mark Rogers,et al.  NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development? , 2007, Trends in pharmacological sciences.

[76]  D. Piomelli,et al.  A neuroscientist's guide to lipidomics , 2007, Nature Reviews Neuroscience.

[77]  J. Trojanowski,et al.  Tau-mediated neurodegeneration in Alzheimer's disease and related disorders , 2007, Nature Reviews Neuroscience.

[78]  D. Kang,et al.  Low‐density lipoprotein receptor‐related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[79]  K. Yanagisawa Role of gangliosides in Alzheimer's disease. , 2007, Biochimica et biophysica acta.

[80]  Lewis E Kazis,et al.  Simvastatin is associated with a reduced incidence of dementia and Parkinson ' s disease , 2007 .

[81]  Mark M. Rasenick,et al.  Lipid raft microdomains and neurotransmitter signalling , 2007, Nature Reviews Neuroscience.

[82]  D. Selkoe,et al.  Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide , 2007, Nature Reviews Molecular Cell Biology.

[83]  W. Klein,et al.  Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease , 2007, The Journal of Neuroscience.

[84]  Richard G. W. Anderson,et al.  Lipid rafts: at a crossroad between cell biology and physics , 2007, Nature Cell Biology.

[85]  Sun Young Shin,et al.  Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism , 2006, Proceedings of the National Academy of Sciences.

[86]  R. Malinow,et al.  AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss , 2006, Neuron.

[87]  J. Slotte,et al.  Sphingolipids and the formation of sterol-enriched ordered membrane domains. , 2006, Biochimica et biophysica acta.

[88]  Pietro De Camilli,et al.  Phosphoinositides in cell regulation and membrane dynamics , 2006, Nature.

[89]  Y. Yamauchi,et al.  Cholesterol sensing, trafficking, and esterification. , 2006, Annual review of cell and developmental biology.

[90]  S. Mizutani,et al.  BACE1 interacts with lipid raft proteins , 2006, Journal of neuroscience research.

[91]  B. Kriem,et al.  Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway , 2006, Neurobiology of Disease.

[92]  R. Vassar,et al.  Isoprenoids and Alzheimer's disease: A complex relationship , 2006, Neurobiology of Disease.

[93]  P. Greengard,et al.  Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[94]  P. Greengard,et al.  Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[95]  G. Johnson Tau phosphorylation and proteolysis: insights and perspectives. , 2006, Journal of Alzheimer's disease : JAD.

[96]  D. Holtzman,et al.  Deletion of Abca1 Increases Aβ Deposition in the PDAPP Transgenic Mouse Model of Alzheimer Disease* , 2005, Journal of Biological Chemistry.

[97]  M. Staufenbiel,et al.  Lack of ABCA1 Considerably Decreases Brain ApoE Level and Increases Amyloid Deposition in APP23 Mice* , 2005, Journal of Biological Chemistry.

[98]  M. Hayden,et al.  The Absence of ABCA1 Decreases Soluble ApoE Levels but Does Not Diminish Amyloid Deposition in Two Murine Models of Alzheimer Disease* , 2005, Journal of Biological Chemistry.

[99]  Steven Mennerick,et al.  Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo , 2005, Neuron.

[100]  P. Schwille,et al.  Lipids as Modulators of Proteolytic Activity of BACE , 2005, Journal of Biological Chemistry.

[101]  B. Strooper,et al.  Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin , 2005, Nature Cell Biology.

[102]  G. Jenkins,et al.  Phospholipase D: a lipid centric review , 2005, Cellular and Molecular Life Sciences CMLS.

[103]  P. Greengard,et al.  Regulation of NMDA receptor trafficking by amyloid-β , 2005, Nature Neuroscience.

[104]  Haipeng Cheng,et al.  Spatial Segregation of γ-Secretase and Substrates in Distinct Membrane Domains* , 2005, Journal of Biological Chemistry.

[105]  M. Wenk The emerging field of lipidomics , 2005, Nature Reviews Drug Discovery.

[106]  R. Vassar,et al.  Statins Cause Intracellular Accumulation of Amyloid Precursor Protein, β-Secretase-cleaved Fragments, and Amyloid β-Peptide via an Isoprenoid-dependent Mechanism* , 2005, Journal of Biological Chemistry.

[107]  T. Kodama,et al.  Association of active γ-secretase complex with lipid rafts Published, JLR Papers in Press, Feburary 16, 2005. DOI 10.1194/jlr.M400333-JLR200 , 2005, Journal of Lipid Research.

[108]  Pritam Das,et al.  Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production , 2005, Nature Medicine.

[109]  E. Pasquale,et al.  EphrinB–EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1 , 2005, Nature Cell Biology.

[110]  H. Hayashi,et al.  Cholesterol homeostasis in neurons and glial cells. , 2005, Seminars in cell & developmental biology.

[111]  R. Nixon Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases , 2005, Neurobiology of Aging.

[112]  R. Tanzi,et al.  Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective , 2005, Cell.

[113]  B. Kriem,et al.  Cytosolic phospholipase A2 mediates neuronal apoptosis induced by soluble oligomers of the amyloid‐β peptide , 2005 .

[114]  G. Prendergast,et al.  Modulation of Statin-Activated Shedding of Alzheimer APP Ectodomain by ROCK , 2005, PLoS medicine.

[115]  Steffen Roßner,et al.  New players in old amyloid precursor protein-processing pathways , 2004, International Journal of Developmental Neuroscience.

[116]  D. Dickson,et al.  Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease , 2004, The Journal of Neuroscience.

[117]  K. Zou,et al.  Modulation of Amyloid Precursor Protein Cleavage by Cellular Sphingolipids* , 2004, Journal of Biological Chemistry.

[118]  R. Nixon Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up. , 2004, The American journal of pathology.

[119]  W. Markesbery,et al.  Regional Membrane Phospholipid Alterations in Alzheimer's Disease , 2004, Neurochemical Research.

[120]  Valentina Gelfanova,et al.  Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß42 by Inhibiting Rho , 2003, Science.

[121]  A. Tall,et al.  Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion* , 2003, Journal of Biological Chemistry.

[122]  D. McKeel,et al.  Specificity and potential mechanism of sulfatide deficiency in Alzheimer's disease: an electrospray ionization mass spectrometric study. , 2003, Cellular and molecular biology.

[123]  L. Puglielli,et al.  Withdrawal: Ceramide stabilizes β-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β-peptide biogenesis , 2003, Journal of Biological Chemistry.

[124]  R. Malinow,et al.  APP Processing and Synaptic Function , 2003, Neuron.

[125]  C. Haass,et al.  Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts , 2003, The Journal of cell biology.

[126]  C. Lemere,et al.  Novel Therapeutic Approach for the Treatment of Alzheimer's Disease by Peripheral Administration of Agents with an Affinity to β-Amyloid , 2003, The Journal of Neuroscience.

[127]  J. Fantini,et al.  Lipid rafts: structure, function and role in HIV, Alzheimer's and prion diseases , 2002, Expert Reviews in Molecular Medicine.

[128]  J. Slotte,et al.  Membrane properties of sphingomyelins , 2002, FEBS letters.

[129]  R. Cowburn,et al.  The Presenilin 1 ΔE9 Mutation Gives Enhanced Basal Phospholipase C Activity and a Resultant Increase in Intracellular Calcium Concentrations* , 2002, The Journal of Biological Chemistry.

[130]  S. Younkin,et al.  Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains , 2002, Neurobiology of Disease.

[131]  B. Hyman,et al.  Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid β-peptide , 2001, Nature Cell Biology.

[132]  D. Riddell,et al.  Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts , 2001, Current Biology.

[133]  Xianlin Han,et al.  Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry , 2001, Journal of neurochemistry.

[134]  C. Bergmann,et al.  Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[135]  J. Dietschy,et al.  Cholesterol metabolism in the brain , 2001, Current opinion in lipidology.

[136]  C. Schweiger [Statins and the risk of dementia]. , 2001, Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology.

[137]  D. Dickson,et al.  Reduction of Aβ accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidylinositol kinase inhibitor wortmannin , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[138]  M. Frosch,et al.  Presenilin-Mediated Modulation of Capacitative Calcium Entry , 2000, Neuron.

[139]  J. Farmer Pleiotropic effects of statins , 2000, Current atherosclerosis reports.

[140]  X. Xu,et al.  The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. , 2000, Biochemistry.

[141]  N. Seidah,et al.  Post-translational processing of b -secretase (BACE) and its ectodomain shedding: the pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid A b production , 2000 .

[142]  S. Gandy,et al.  The Phosphatidylinositol 3‐Kinase Inhibitor Wortmannin Alters the Metabolism of the Alzheimer's Amyloid Precursor Protein , 1999, Journal of neurochemistry.

[143]  B. Strooper,et al.  Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[144]  Y. Ihara,et al.  Amyloid β‐protein (Aβ) associated with lipid molecules: immunoreactivity distinct from that of soluble Aβ , 1997 .

[145]  D. Selkoe,et al.  Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain , 1996, Neurobiology of Disease.

[146]  M. Wallace Effects of Alzheimer's disease-related beta amyloid protein fragments on enzymes metabolizing phosphoinositides in brain. , 1994, Biochimica et biophysica acta.

[147]  J. Haines,et al.  Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.

[148]  K. Kristensson,et al.  Ubiquinone, dolichol, and cholesterol metabolism in aging and Alzheimer's disease. , 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[149]  G. Lauc,et al.  Human brain gangliosides in development, aging and disease. , 1991, The International journal of developmental biology.

[150]  J. Talan-Hranilović,et al.  Brain gangliosides in Alzheimer's disease. , 1990, Journal fur Hirnforschung.

[151]  J. Hawthorne,et al.  Reduced Phosphoinositide Concentrations in Anterior Temporal Cortex of Alzheimer‐Diseased Brains , 1987, Journal of neurochemistry.

[152]  John Terraine,et al.  A Complex Relationship , 1981 .

[153]  A. Baer The genetic perspective , 1977 .